Test Price
2,800 AED✅ Home Collection Available
ACSF3 Gene Test for Combined Malonic and Methylmalonic Aciduria (NGS) in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) accredited NGS processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Mandatory pre- and post-test genetic counseling with a DHA-licensed consultant medical geneticist.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731; self-pay also accepted.
Test Overview & Methodology
The ACSF3 Gene NGS Test identifies pathogenic variants linked to Combined Malonic and Methylmalonic Aciduria, a rare inborn error of metabolism. This advanced sequencing panel provides definitive molecular diagnosis for affected individuals, carrier screening, and peace‑of‑mind testing, delivered with a 3–4 week turnaround at 2800 AED.
| Feature | Our Test (ACSF3 NGS – UAE) | Closest Alternative |
|---|---|---|
| Methodology | NGS (Next‑Generation Sequencing) with full exon coverage | Targeted Sanger sequencing (limited to known variants) |
| Diagnostic Accuracy | 99.9% sensitivity, ISO‑accredited bioinformatics pipeline | ~95% for single‑variant panels |
| Turnaround Time | 3–4 Weeks with dedicated clinical report | 6–8 Weeks |
| Home Collection | Hospital‑grade cold‑chain 8 AM–11 PM, included | Often not available |
| Genetic Counseling | Mandatory pre‑ & post‑test session (DHA‑compliant) | May be optional or absent |
Physician Insight & Safety Protocols
“The ACSF3 gene test is a fundamental tool for diagnosing Combined Malonic and Methylmalonic Aciduria, yet a positive finding must always be correlated with the patient’s full clinical picture and metabolic work‑up. I strongly caution against any alteration of prescribed therapies based solely on genetic data. This test is one piece of a larger diagnostic framework and should be interpreted by a qualified medical geneticist.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
⚠ Medication Advisory
Do not discontinue or alter any prescribed medication or metabolic supplement without consulting your treating physician. This genetic test is a diagnostic aid, not a substitute for ongoing clinical care.
Exclusion Criteria & Emergency Red Flags
- Specimen Rejection: Incorrect tube, insufficient volume, or compromised cold‑chain integrity.
- Regulatory Exclusions: Minors (<18 years) require documented legal guardian consent per UAE Federal Law.
- Medical Contraindications: Cannot be performed during acute metabolic crisis; stabilise patient first.
- ER Red Flags (seek immediate emergency care): Vomiting, lethargy, hypotonia, seizures, or loss of consciousness in suspected metabolic decompensation.
- Data Privacy: All genetic data handled under UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection and Federal Law No. 2 of 2019.
Patient FAQ & Clinical Guidance
1. What is the ACSF3 gene test and why is it important for UAE patients?
The ACSF3 gene test uses next‑generation sequencing to detect pathogenic mutations causing Combined Malonic and Methylmalonic Aciduria, a treatable metabolic disorder. Early diagnosis enables targeted dietary and cofactor therapy, preventing irreversible neurological damage. In the UAE, where consanguinity rates are significant, this test is crucial for family planning and newborn‑onset metabolic screening.
2. How is the home collection performed and is it safe for genetic testing?
Our DHA‑licensed phlebotomist arrives at your home using a sterile, cold‑chain certified kit that preserves DNA integrity from draw to lab. The entire process follows ISO 9001:2015 standards: ID verification, sample labelling, and temperature monitoring ensure the specimen remains at 2‑8°C, guaranteeing stable genetic material for accurate NGS analysis.
3. Will my health insurance cover this 2800 AED genetic test?
Many UAE insurers cover NGS‑based genetic tests when medically justified; we verify your policy via WhatsApp before collections using your Emirates ID and insurance card. If pre‑authorisation is needed, our team coordinates directly with your physician and the payer. Self‑pay option is also available at 2800 AED inclusive of counselling and report.
UAE Regulatory & Data Privacy Adherence
This laboratory test is performed under the regulatory framework of the Dubai Health Authority (DHA Facility License No. 1143). All genetic data are processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory is ISO 9001:2015 certified (INT/EGQ/2509DA/3139), ensuring international standards of quality and confidentiality.
Clinical & Logistical Metadata
| Test Name | ACSF3 Gene Test for Combined Malonic and Methylmalonic Aciduria (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (or tissue biopsy) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM–11 PM) |
| Methodology Used | Next‑Generation Sequencing (NGS) – full exon coverage |
| ICD-10-CM Code | E71.120, E71.1, Z13.79 |
| LOINC Code | 101872-5 – ACSF3 gene [Presence] in Blood or Tissue by Molecular genetics method |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians