Test Price
2,800 AEDโ Home Collection Available
ABCB1 Gene Inflammatory Bowel Disease Type 13 Genetic Test in UAE โ 2800 AED
Executive Summary & Core Metrics
The ABCB1 gene Inflammatory Bowel Disease Type 13 (IBD13) susceptibility test uses Next Generation Sequencing (NGS) with 99.9% diagnostic sensitivity and 99.8% specificity, processed at our ISO-accredited facility in Dubai Healthcare City. This assay identifies pathogenic variants in the ABCB1 gene that increase risk for Crohnโs disease and ulcerative colitis, enabling personalized surveillance and counseling.
- Precision: 99.9% sensitivity / 99.8% specificity via NGS with confirmatory Sanger validation.
- Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AMโ11 PM).
- Post-Test Support: Telephonic clinical guidance from our Consultant Medical Geneticist.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This genetic screening analyzes the ABCB1 gene (encoding P-glycoprotein) for variants linked to Inflammatory Bowel Disease type 13. Our NGS workflow covers all coding exons, splice sites, and regulatory regions, exceeding clinical standards. A detailed clinical history and pedigree are recommended before testing.
| Feature | Our Test (DNA Labs UAE) | Closest Alternative |
|---|---|---|
| Precision | 99.9% Sensitivity / 99.8% Specificity | Variable (often <98%) |
| Methodology | NGS with confirmatory Sanger validation | Sanger or targeted genotyping only |
| Turnaround Time | 3 to 4 Weeks (expedited available) | 4 to 6 Weeks |
| DHA/MOHAP Compliance | Full (License 1143, ISO 9001:2015) | Partial or uncertain |
Physician Insight & Safety Protocols
"As a consultant medical geneticist, I stress that ABCB1 variants indicate susceptibility, not disease certainty. A negative result does not rule out IBD; a positive result warrants enhanced surveillance and gastroenterology consultation, not immediate medication changes. All findings should be discussed with your healthcare provider."
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA License 9294403
Important Medication Advisory
โ ๏ธ Do not discontinue any prescribed medication without consulting your physician. Genetic test results should not be used to alter current therapy without professional medical advice.
Safety Exclusion Criteria & Emergency Red Flags
Exclusion Criteria
- This test is a susceptibility screen only; it is not intended for acute diagnosis of active IBD flares.
- Patients with known hematological malignancies or recent blood transfusion may yield ambiguous results due to somatic mosaicism or donor DNA.
Emergency Red Flags (Seek Immediate Care)
- Severe abdominal pain, rectal bleeding, high fever, or inability to tolerate oral intake โ go to the nearest Emergency Department.
- Sudden onset of jaundice, confusion, or severe dehydration in a patient with known IBD warrants urgent medical evaluation.
Patient FAQ & Clinical Guidance
1. What is the ABCB1 gene and how does it relate to Inflammatory Bowel Disease type 13?
The ABCB1 gene encodes P-glycoprotein, a drug transporter that influences intestinal barrier function and immune homeostasis. Pathogenic variants in this gene can increase the risk of IBD type 13 by altering epithelial integrity and host-microbe interactions.
2. How should I prepare for this genetic test and is a blood sample always required?
A standard venous whole blood sample is collected by our VIP mobile phlebotomy team at your home. You may continue normal diet and medications unless your doctor specifies otherwise. Prior genetic counselling is recommended to document family history and facilitate result interpretation.
3. What happens after I receive my results and can I consult a specialist?
You will receive a comprehensive report reviewed by our Consultant Medical Geneticist, along with a telephonic post-test counselling session to explain your personal risk profile. Referrals to gastroenterologists or clinical geneticists can be arranged based on findings.
4. Is the test covered by insurance and how do I use my policy?
We support direct billing with most UAE insurers. Send your policy details via WhatsApp to +971 54 548 8731 for a pre-authorization check. A valid referral from your gastroenterologist is required for insurance processing.
UAE Regulatory & Data Privacy Adherence
This genetic test is performed at DNA Labs UAE, a DHA-licensed facility (License No. 1143) operating under the highest standards of data protection and clinical safety. We comply with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) โ ensuring patient genetic data is encrypted and accessed only on a need-to-know basis.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields โ governing the secure transmission of electronic health records and genetic test results.
- Federal Decree-Law No. 4 of 2016 on Medical Liability โ reinforcing informed consent and clinical accountability for genetic counseling and test interpretation.
Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). Patient data is stored in UAE-based servers in compliance with the Dubai Health Authorityโs data governance framework.
Clinical & Logistical Metadata
| Test Name | ABCB1 Gene Inflammatory Bowel Disease Type 13 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks (expedited available) |
| Sample Type / Matrix | Whole Blood (venous) โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection |
| Methodology Used | Next Generation Sequencing (NGS) with confirmatory Sanger validation |
| ICD-10-CM Code | Z15.09 (Encounter for genetic testing for disease susceptibility) |
| LOINC Code | 21646-6 (ABCB1 gene mutation analysis) |
| DHA Facility License & Address | License No. 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians