Test Price
2,800 AED✅ Home Collection Available
ABCA3 Gene Surfactant Metabolism Dysfunction Type 3 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين ABCA3 لاضطراب استقلاب المادة الخافضة للتوتر السطحي من النوع 3 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary | ملخص تنفيذي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing (ISO 9001:2015 Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation with our DHA-licensed genetic counselors.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي: يقدم هذا التحليل الجيني شاملًا باستخدام تقنية التسلسل من الجيل التالي (NGS) لتشخيص اضطراب استقلاب المادة الخافضة للتوتر السطحي من النوع 3 بدقة 99.9%، مع خدمة سحب الدم المنزلي الفاخر المطابقة لمعايير الآيزو ودعم التأمين الصحي المباشر.
Test Overview
This advanced NGS test sequences the entire ABCA3 gene to detect pathogenic variants associated with Surfactant Metabolism Dysfunction Type 3, a rare but often fatal neonatal respiratory disorder. Early diagnosis empowers timely clinical intervention and family planning.
يقوم هذا الاختبار بتسلسل جين ABCA3 كاملاً للكشف عن الطفرات المسببة لاضطراب استقلاب الفاعل بالسطح النوع 3، وهو مرض تنفسي نادر يصيب حديثي الولادة. التشخيص المبكر يتيح تدخلًا سريريًا مناسبًا وتخطيطًا عائليًا أفضل.
| Feature | Our Test (ABCA3 NGS) | Closest Alternative |
|---|---|---|
| Methodology | Next-Generation Sequencing (Illumina NovaSeq) | PCR-based targeted mutation panel |
| Analytical Sensitivity | 99.9% for SNVs, indels, CNVs | ~95% (misses rare variants) |
| Turnaround Time | 3 – 4 Weeks | 1 – 2 Weeks (limited scope) |
| Coverage | Full coding region ± flanking intronic sequences | Pre‑selected hotspot mutations only |
| Clinical Utility | Definitive diagnosis, carrier screening, prenatal planning | Preliminary screening, often requires reflex to NGS |
Physician Insight & Safety Protocol
“As a clinician with over two decades of experience in the UAE, I understand the anxiety surrounding genetic testing for your newborn. This test is a critical tool, but results must be correlated with clinical findings and managed by a multidisciplinary team. Please do not delay urgent care while awaiting results.” — Dr. Prabhakar Reddy, DHA License 61713011
⚠️ Medication Warning: Do not discontinue prescribed medication or oxygen therapy without consulting your doctor.
Safety Exclusion Criteria & ER Red Flags
- Exclusion Criteria: Blood collection should not proceed if the patient has active hemolysis, recent blood transfusion (within 4 weeks), or is receiving extracorporeal membrane oxygenation (ECMO).
- Emergency Red Flags: If the infant exhibits severe respiratory distress with grunting, nasal flaring, cyanosis (blue skin), or apnea, seek emergency medical attention immediately. Genetic results do not replace urgent clinical judgment.
- Mandatory Pre‑Test Requirement per UAE Law: A genetic counselling session and a three‑generation pedigree chart must be completed before sample collection. See FAQ for details.
Patient FAQ & Clinical Guidance
Snippet: Identify ABCA3 gene mutations causing fatal neonatal lung disease via NGS for definitive genetic diagnosis.
The test deciphers the entire coding sequence of the ABCA3 gene, which is critical for surfactant production in the lungs. Mutations lead to Surfactant Metabolism Dysfunction Type 3, a leading cause of severe respiratory distress in term newborns. Results guide life‑saving interventions such as lung transplantation candidacy and inform family genetic counselling.
Snippet: Home blood draw by your DHA-licensed phlebotomist, results in 3–4 weeks for comprehensive genetic analysis.
A single blood sample (2–5 mL in EDTA tube) is collected via our VIP home service, transported in cold‑chain packaging to our ISO‑certified lab. NGS sequencing, data analysis, and clinical interpretation take 3–4 weeks. A secure report is delivered through our patient portal, and a telephonic consultation is arranged to explain the findings.
Snippet: Mandatory genetic counseling and a three-generation pedigree chart must precede testing under UAE genetic law.
Yes, in compliance with Federal Decree‑Law No. 41 of 2024 and the UAE CDS Law 2026 for minors, all individuals undergoing genetic testing must first attend a certified genetic counselling session. We arrange a virtual or in‑person session where a genetic counsellor constructs a three‑generation pedigree and explains the potential implications. The pedigree is a required part of your pre‑ documentation.
UAE Regulatory Adherence: This service is fully compliant with Federal Decree‑Law No. 41 of 2024 (Art. 87), CDS Law 2026 (protection of minors), and the UAE Personal Data Protection Law (PDPL). All genetic data is processed with the highest confidentiality standards.
Accreditation: ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) ensuring laboratory quality management and data integrity.
DHA Facility License: 9834453. All phlebotomists hold current DHA licenses.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians