Test Price
1,200 AEDโ Home Collection Available
NTRK3 Gene Rearrangement Test (FISH) in the UAE โ 1,200 AED | DHA Licensed
Executive Summary & Core Metrics
Core Metrics
Test Overview & Methodology
The NTRK3 Gene Rearrangement Test (FISH) detects oncogenic fusions involving the NTRK3 gene in tumor tissue, guiding targeted therapy with TRK inhibitors. This advanced molecular test is essential for personalized cancer care across oncology, pediatric tumors, and precision medicine in the UAE.
The test utilizes fluorescence in situ hybridization (FISH) with break-apart probes targeting the NTRK3 locus, providing high specificity for known fusion partners.
| Feature | Our Test โ NTRK3 FISH | Closest Alternative โ NTRK NGS Panel |
|---|---|---|
| Method | FISH (Fluorescence In Situ Hybridization) with break-apart probes | Next-Generation Sequencing (NGS) multigene panel |
| Precision | 99.9% targeted sensitivity for known NTRK3 fusions | Broader detection but variable fusion calling |
| Turnaround Time | 7โ8 days | 10โ14 days |
| Price | 1,200 AED | Typically 2,000โ3,500 AED |
| Regulatory | DHA/MOHAP approved, ISO 9001:2015 | Vendor-dependent certification |
Physician Insight & Safety Protocols
โAs a DHA-licensed Consultant Medical Genetics, I understand that waiting for genetic test results can be a source of anxiety. However, this precise FISH-based analysis provides crucial information for your oncologist to select the most effective targeted therapy. Please continue all prescribed medications until your doctor reviews the results with you.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Do Not Discontinue Prescribed Medication
โ It is critical to continue all prescribed medications until your oncologist reviews the test results. Abrupt cessation of therapy may lead to adverse outcomes. Always consult your treating physician before making any changes.
Exclusion Criteria & Safety Flags
- Sample Type: Only formalin-fixed paraffin-embedded (FFPE) tumor tissue blocks or fresh tissue in approved transport medium are accepted. Liquid biopsies (blood) are not valid for this FISH assay.
- Clinical Exclusions: Patients with active bleeding disorders or severe coagulopathies must obtain medical clearance before surgical biopsy.
- Immediate ER Action: If you experience sudden severe pain at the biopsy site, uncontrolled bleeding, fever >38.5ยฐC, or signs of infection, seek emergency care immediately.
Patient FAQ & Clinical Guidance
1. What is an NTRK3 gene rearrangement test, and why is it done?
The NTRK3 gene rearrangement test detects cancer-driving fusions in tumor tissue, enabling personalized targeted therapy decisions. This test is used by medical oncologists, pediatric specialists, and precision medicine experts to identify patients who may benefit from TRK inhibitor drugs, and is performed on a biopsy sample using highly specific FISH technology.
2. How is the test performed and how long for results?
A biopsy sample undergoes FISH testing for NTRK3 rearrangements, yielding accurate results in 7โ8 days. After a physician collects a small tumor tissue specimen, the sample is processed in our ISO-certified laboratory; you will be notified via WhatsApp once the report is ready for telephonic review.
3. Do I need a doctorโs prescription for this test in the UAE?
A valid DHA-licensed doctor's prescription is required, except for surgery clearance, pregnancy, or travel certificates. This ensures compliance with UAE medical regulations; patients preparing for international travel, undergoing surgery, or in pregnancy cases may request the test without a prescription after documentation review.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number: 1143 and adheres to the highest standards of data privacy and security as per Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Additionally, we comply with Federal Decree-Law No. 4 of 2016 on Medical Liability to ensure patient safety and clinical accountability. Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | NTRK3 Gene Rearrangement Test (FISH) |
| Price (AED) | 1,200 AED |
| Turnaround Time | 7โ8 business days |
| Sample Type / Matrix | Formalin-fixed paraffin-embedded (FFPE) tumor tissue blocks or fresh tissue in approved transport medium |
| Methodology Used | Fluorescence In Situ Hybridization (FISH) with break-apart probes |
| ICD-10-CM Code | C80.1 |
| LOINC Code | 86553-5 |
| DHA Facility License & Address | DHA Facility License Number: 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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