Test Price
2,800 AED✅ Home Collection Available
FMR1 Gene (Premature Ovarian Failure Type 1) Genetic Test in UAE | 2,800 AED | DHA-Trusted Diagnostics
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO-Accredited NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Genetic Counseling with a DHA-licensed consultant medical geneticist.
- Insurance Direct Billing: Verify your plan instantly via WhatsApp at +971 54 548 8731.
This NGS-based genetic test examines the FMR1 gene for CGG repeat expansions that cause Fragile X-associated Primary Ovarian Insufficiency (FXPOI), the most common inherited form of premature ovarian failure. It is indicated for women with unexplained infertility, early menopause, or a family history of Fragile X disorders.
Test Overview & Methodology
This next-generation sequencing (NGS) assay interrogates the full FMR1 gene for CGG trinucleotide repeat expansions, including AGG interruption pattern analysis. The test classifies alleles as normal (≤44 repeats), intermediate (45–54), premutation (55–200), or full mutation (>200), directly informing fertility prognosis, family planning, and offspring risk of Fragile X syndrome. Bioinformatics interpretation is validated against ClinVar and HGMD Professional databases.
| Feature | Our Test (NGS – FMR1 Full Gene) | Closest Alternative (PCR + Southern Blot) |
|---|---|---|
| Methodology | Next‑Generation Sequencing with bioinformatics validated against ClinVar & HGMD Professional | Conventional PCR followed by Southern blotting |
| Resolution | Exact CGG repeat number + AGG interruption pattern; detects low-level mosaicism | Size range only, limited sensitivity for low-level mosaicism |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Sample Type | Whole Blood, Extracted DNA, or One Drop Blood on FTA Card | Whole Blood (typically 3‑5 ml) |
| Price | 2,800 AED | ~3,500 AED |
Comparison based on current UAE diagnostic laboratory standards. Pricing may vary by insurer.
Physician Insight & Safety Protocols
"An FMR1 premutation is a critical biomarker, not a definitive prognosis. By integrating the precise CGG repeat count with anti-Müllerian hormone levels and antral follicle count, we can offer a personalized reproductive roadmap. Every patient deserves comprehensive genetic counseling to navigate these results with confidence."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory – Medication and Clinical Context
Do not discontinue prescribed medications or hormone replacement therapy without consulting your treating physician. This test does not replace a comprehensive clinical evaluation and should be interpreted alongside ovarian reserve markers and pelvic imaging.
Safety Exclusion & Emergency Red Flags
- Exclusion: Genetic testing for minors is strictly governed by UAE Federal Law No. 2 of 2019 – parental or guardian consent and mandatory genetic counseling are required.
- Exclusion: This test is not a diagnostic tool for active ovarian tumors or acute pelvic pathology.
- Immediate ER Visit Needed: If you develop sudden severe pelvic or abdominal pain, heavy vaginal bleeding, or signs of shock during the sample collection process, go directly to the emergency department.
Patient FAQ & Clinical Guidance
1. What does the FMR1 gene test diagnose?
Snippet: It detects CGG repeat expansions in the FMR1 gene to diagnose Fragile X‑associated primary ovarian insufficiency. By measuring the exact number of CGG repeats, the test classifies alleles as normal, intermediate, premutation, or full mutation, directly impacting fertility, family planning, and risk of Fragile X syndrome in offspring. Pre‑ and post‑test genetic counseling is included to interpret results within your personal and family health context.
2. How should I prepare for this genetic test?
Snippet: No fasting or medication changes are required; a simple blood draw or DNA sample on an FTA card suffices. You may eat and drink normally. If you are taking blood‑thinning medication, inform the phlebotomist during home collection to ensure proper hemostasis. The sample can be collected comfortably at your home between 8 AM and 11 PM, and is transported in a temperature‑controlled cold‑chain box to our central lab.
3. How long until I receive results, and what do they mean?
Snippet: Results are returned in 3 to 4 weeks, classifying repeat length as normal, intermediate, premutation, or full mutation. Each category carries distinct clinical implications: a premutation indicates FXPOI risk but does not predict exact menopause timing; a full mutation can cause Fragile X syndrome in male offspring. Our board‑certified genetic counselor will guide you through the report and discuss next steps, including fertility preservation options and family planning.
4. Is home sample collection available for this test?
Snippet: Yes, a certified phlebotomist will visit your home between 8 AM and 11 PM daily. The collected whole blood or FTA card sample is transported via a temperature‑controlled cold‑chain courier directly to our ISO‑accredited laboratory. This service is included in the test price with no additional fee for standard residential locations within Dubai.
5. Does insurance cover the FMR1 genetic test?
Snippet: Coverage depends on your specific plan; we offer direct billing for many UAE insurers. Submit your policy details via WhatsApp at +971 54 548 8731 for a pre‑authorization check. For self‑pay patients, the test is priced at 2,800 AED including collection, analysis, and a genetic counseling session.
UAE Regulatory & Data Privacy Adherence
Your data is protected under UAE Federal Law
All genetic information is processed in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring patient consent, safety, and privacy throughout the diagnostic journey. Our laboratory maintains ISO 9001:2015 certification and operates under DHA Facility License 1143.
Clinical & Logistical Metadata
| Test Name | FMR1 Gene (Premature Ovarian Failure Type 1) – NGS Full Gene Analysis |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) with bioinformatics validated against ClinVar & HGMD Professional |
| ICD-10-CM Code | E28.3 (Primary ovarian failure) |
| LOINC Code | 21673-2 (FMR1 gene CGG repeat analysis) |
| DHA Facility License & Laboratory Address | DHA License 1143 · Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians