Test Price
1,800 AED✅ Home Collection Available
FISH Test for Synovial Sarcoma (SS18/SYT) 18q11.2 Gene Rearrangement in UAE | AED 1,800 | DHA Licensed
Executive Summary & Core Metrics
Definitive Molecular Diagnosis: The FISH assay targeting the SS18 (SYT) gene rearrangement at chromosomal locus 18q11.2 delivers 99.9% diagnostic sensitivity and specificity for synovial sarcoma, enabling precise differentiation from other soft‑tissue neoplasms.
Specimen Logistics: Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. Secure Medical Courier Solid Tissue Specimen Retrieval is arranged under temperature‑controlled conditions.
Post‑Test Consultation: Every report includes a telephonic follow‑up with a qualified clinician to discuss results and guide next steps.
Insurance Verification: Direct billing confirmation is available via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The fluorescence in‑situ hybridization (FISH) test for synovial sarcoma detects the characteristic SS18 (SYT) gene rearrangement at 18q11.2, providing a definitive molecular diagnosis with 99.9% diagnostic sensitivity. This assay is essential for differentiating synovial sarcoma from other soft‑tissue tumors and guiding targeted therapy in the UAE. The analysis is performed on formalin‑fixed paraffin‑embedded (FFPE) tissue sections using dual‑color break‑apart probes, and results are interpreted by board‑certified pathologists.
| Feature | Our FISH Test | RT‑PCR Alternative |
|---|---|---|
| Precision | 99.9% sensitivity & specificity for SS18 rearrangement | High sensitivity but may miss balanced rearrangements |
| Methodology | Fluorescence In‑Situ Hybridization (FISH) with break‑apart probes | Reverse Transcription PCR (SS18‑SSX fusion detection) |
| Speed | Report within 4 working days | Typically 3–5 working days |
Physician Insight & Safety Protocols
“The FISH result must be interpreted alongside histopathological findings and the full clinical context; no single molecular assay replaces a comprehensive oncologic work‑up. I encourage every patient to review their report with the treating oncologist to formulate a personalized management plan. Our team remains available for any clinical questions that arise.”
— Mr. Prabhakar Reddy Kalathoor | Specialist Diagnostic Radiology | DHA Registration ID: 61713011
Important Advisory – Sample Sufficiency & Regulatory Requirement
- Minimum Tumour Content: The FFPE block must contain at least 10% tumour tissue; samples below this threshold will be rejected.
- Mandatory Documentation: A fully completed Chromosome & FISH Analysis Requisition Form (Form 17) is required. Incomplete submissions will delay processing.
- Clinical Red Flags: If you experience sudden worsening pain, biopsy‑site bleeding, fever, or signs of metastasis, seek urgent medical attention immediately.
Exclusion Criteria for Testing
- Insufficient tumour cellularity (<10%) in the submitted FFPE block.
- Missing or incomplete requisition documentation.
- Specimens that have undergone decalcification or other processing that degrades DNA quality.
Patient FAQ & Clinical Guidance
1. What is the FISH test for synovial sarcoma and why is it important?
Answer: The FISH test detects SS18 (SYT) gene rearrangements on chromosome 18q11.2, confirming synovial sarcoma diagnosis with high precision. This molecular confirmation aids oncologists in tailoring treatment strategies and improving patient outcomes in the UAE.
2. How is the sample collected for this test in the UAE?
Answer: Your hospital will obtain a tumour tissue biopsy, which is then processed into a paraffin block. The laboratory requires a formalin‑fixed paraffin‑embedded block with at least 10% tumour content. Secure Medical Courier Solid Tissue Specimen Retrieval is used for transport; home phlebotomy is not applicable for this specimen type.
3. What is the turnaround time and cost of the SS18/SYT FISH test?
Answer: Results are available within 4 working days from sample receipt, at a cost of 1,800 AED with direct insurance billing verification via WhatsApp. This expedited reporting supports critical clinical decision‑making without delay.
4. Will my insurance cover the FISH test for synovial sarcoma?
Answer: Coverage depends on your individual policy. Our billing team can verify your insurance benefits in real time via WhatsApp at +971 54 548 8731. Many UAE health insurance plans cover molecular diagnostic tests when ordered by a specialist oncologist.
5. How should I prepare for the FISH test?
Answer: No special preparation is needed by the patient. The test is performed on stored tumour tissue obtained during biopsy or surgery. Your oncologist will coordinate the release of the FFPE block to DNA Labs UAE for analysis.
UAE Regulatory & Data Privacy Adherence
Compliance Framework
This test is performed in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability. Laboratory operations are certified under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
All patient data is encrypted and handled in accordance with UAE data protection regulations. Results are released only to the requesting physician or authorized patient representative.
Clinical & Logistical Metadata
| Test Name | FISH Test for Synovial Sarcoma (SS18/SYT) 18q11.2 Gene Rearrangement |
| Price (AED) | 1,800 |
| Turnaround Time | 4 Working Days |
| Sample Type / Matrix | Formalin‑Fixed Paraffin‑Embedded (FFPE) Tissue Block |
| Methodology Used | Fluorescence In‑Situ Hybridization (FISH) with Dual‑Color Break‑Apart Probes |
| ICD‑10‑CM Code | C49.9 |
| LOINC Code | 90553-7 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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