Test Price
750 AEDโ Home Collection Available
FISH Opposite Sex Bone Marrow Transplant (XX/XY) Test in UAE | 750 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Sample Collection: Hospital Extraction Only โ Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
The FISH Opposite Sex Bone Marrow Transplant (XX/XY) Test uses fluorescence in-situ hybridization to detect donor-derived cells with sex chromosomes opposite to the recipient, providing a precise measure of engraftment after transplantation.
| Feature | Our Test (ISO-Accredited FISH) | Standard STR Chimerism |
|---|---|---|
| Methodology | FISH (Fluorescence In-Situ Hybridization) | STR-PCR Analysis |
| Target | Sex chromosome specific (XX/XY) donor cells | Microsatellite markers, not sex-dependent |
| Speed (TAT) | 4 Working Days | 7โ10 Working Days |
| Sensitivity | โฅ 0.1% donor cells | 1โ5% lower limit |
| Price | 750 AED | Varies (often >900 AED) |
Physician Insight & Safety Protocols
โFISH analysis for opposite-sex BMT engraftment offers unparalleled sensitivity, yet it must be correlated with clinical evolution and full blood counts. Results indicating mixed chimerism should prompt a multidisciplinary review before any therapeutic changes. Patients must never self-adjust immunosuppression based solely on this report.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Medication Advisory
โ Medication Warning
Do not discontinue prescribed medication without consulting your doctor. Abrupt cessation of immunosuppressants can precipitate severe graft-versus-host disease or graft rejection.
Exclusion Criteria (Patient Safety):
- No documented donor-recipient sex mismatch (e.g., same-sex transplant โ test not applicable).
- Recent whole blood or platelet transfusion within 7 days may cause false-positive donor signals.
- Active severe hemolysis or clotting in sample.
Emergency Red Flags: If you experience unexplained fever >100.4ยฐF (38ยฐC), extensive rash, jaundice, or bleeding, seek immediate medical attention at the nearest DHA-licensed facility. These may indicate acute graft failure or severe GVHD, require urgent management.
Patient FAQ & Clinical Guidance
1. Why is FISH used for opposite-sex bone marrow transplant monitoring?
FISH detects donor-derived cells with opposite-sex chromosomes (XX in male recipient or XY in female recipient) to quantify engraftment success. The technique counts cells bearing the donorโs sex chromosome in bone marrow or peripheral blood, providing a direct and rapid assessment of donor chimerism without the need for complex DNA amplification. It is recommended by DHA guidelines for all sex-mismatched transplant recipients at defined intervals post-transplant.
2. How should I prepare for the test?
No fasting required; however, inform the phlebotomist of any recent blood transfusions which can skew donor chimerism results. A mandatory Chromosome & FISH Analysis Requisition Form (Form 17) must be completely filled. Samples (5 mL whole blood or 4 mL bone marrow in green-top sodium heparin tubes) are kept at room temperature (18โ22ยฐC) during transport โ never freeze. Our cold-chain logistics team ensures strict compliance with these preanalytical requirements, with collection occurring only at accredited hospital facilities.
3. When will I receive my results and how are they interpreted?
Results are available in 4 working days and are reported as percentage of donor XX or XY cells present. A report will indicate the percentage of host and donor cells. Full donor chimerism (>95% donor cells) typically indicates successful engraftment. Mixed chimerism may require closer follow-up. A telephonic consultation with our DHA-certified specialist is offered to explain your individual findings.
UAE Regulatory & Data Privacy Adherence
Data Protection Compliance: This test is performed in full accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted, stored within UAE borders, and accessed only by authorized clinical personnel. Clinical safety and patient consent abide by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | FISH Opposite Sex Bone Marrow Transplant (XX/XY) |
| Price (AED) | 750 AED |
| Turnaround Time | 4 Working Days |
| Sample Type / Matrix | Bone Marrow Aspirate or Peripheral Whole Blood (Green-top Sodium Heparin Tube) |
| Methodology Used | Fluorescence In-Situ Hybridization (FISH) |
| ICD-10-CM Code | Z94.8 (Bone marrow transplant status) |
| LOINC Code | 44508-3 (Chimerism study by FISH) |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians