Test Price
750 AED✅ Home Collection Available
FISH for Trisomy 21 (Down Syndrome) in UAE | 750 AED | 2026 DHA Guidelines
تحليل FISH لتشخيص تثلث الصبغي 21 (متلازمة داون) في الإمارات | 750 درهم | 2026 معايير هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139)
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain, VIP Mobile Phlebotomy
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
الملخص التنفيذي
حساسية تشخيصية بنسبة 99.9%، خدمة جمع عينات منزلية معتمدة بمعايير سلسلة التبريد المعتمدة من ISO، إرشادات سريرية هاتفية بعد الفحص، تحقق من تغطية التأمين عبر واتساب.
Overview
The FISH (Fluorescence In-Situ Hybridization) test for Trisomy 21 rapidly detects an extra copy of chromosome 21 in fetal cells from amniotic fluid, chorionic villus sampling (CVS), or cord blood, providing a definitive prenatal diagnosis of Down syndrome within 4 days. This targeted molecular cytogenetic technique offers >99% accuracy and is a cornerstone of modern prenatal genetic care in the UAE.
يكشف اختبار FISH (التهجين الموضعي المتألق) عن وجود نسخة إضافية من الصبغي 21 في الخلايا الجنينية خلال 4 أيام بدقة تتجاوز 99%، وهو حجر الزاوية في الرعاية الجينية السابقة للولادة.
| Feature | Our Test (FISH) | Closest Alternative (Karyotype) |
|---|---|---|
| Methodology | Fluorescence In-Situ Hybridization | Cell culture & chromosomal banding |
| Turnaround Time | 4 days | 10–14 days |
| Precision for Trisomy 21 | >99% | >99.5% (but requires viable cells) |
| Sample Types | Amniotic fluid, CVS, cord blood | Same, plus fibroblasts |
Physician Insight & Safety Protocol
"As a senior clinical diagnostician, I remind every patient that FISH results must always be correlated with ultrasound findings and detailed family history – a single test alone cannot tell the full clinical story. A positive FISH result for Trisomy 21 is exceedingly reliable, but a negative result does not exclude other chromosomal anomalies that may require full karyotyping. Please refrain from making any irreversible decisions before discussing the report with your genetic counselor or obstetrician."
— Dr. PRABHAKAR REDDY, DHA License: 61713011
Medication Warning: Do not discontinue prescribed medication without consulting your doctor.
Any adjustment to maternal or fetal management must be made under direct medical supervision, irrespective of the test outcome.
🛡️ Safety & Exclusion Criteria
- Contraindicated in active vaginal bleeding, placenta previa, severe maternal coagulopathy, or known allergy to sodium heparin.
- Not recommended if there is an active uterine infection or if the mother has a significant risk of preterm labor.
- Emergency Red Flags: Seek immediate medical care if you experience severe abdominal pain, heavy vaginal bleeding, fluid leakage, or fever >38°C following the invasive sampling procedure.
Pre‑Test Information: A duly filled Chromosome & FISH analysis Requisition Form (Form 17) and Prenatal Genetic Testing Consent Form (Form 18) are mandatory. No drug or supplement avoidance is required for the collection itself.
Patient FAQ & Clinical Guidance
1. What is the FISH test for Down syndrome?
The FISH test is a rapid prenatal molecular assay that detects an extra chromosome 21 in fetal cells, confirming Down syndrome with over 99% accuracy within 4 days. It uses fluorescent DNA probes that bind specifically to chromosome 21 regions, providing a faster answer than traditional karyotyping.
اختبار FISH هو فحص جزيئي سريع قبل الولادة يكشف عن وجود نسخة إضافية من الصبغي 21 في الخلايا الجنينية، مؤكداً متلازمة داون بدقة تزيد عن 99% خلال 4 أيام.
2. How is the sample collected for the Trisomy 21 FISH in Dubai?
Sample collection involves a minimally invasive procedure—amniocentesis, CVS, or cordocentesis—performed by a skilled specialist under continuous ultrasound guidance. Our dedicated home collection team coordinates the entire process, ensuring cold-chain transport and VIP phlebotomy services at your convenience.
يتم جمع العينة عبر إجراء طفيف التوغل مثل بزل السلى أو أخذ عينة من الزغابات المشيمية أو الحبل السري بواسطة أخصائي متمرس تحت توجيه الموجات فوق الصوتية، مع خدمة منزلية متميزة وسلسلة تبريد معتمدة.
3. What do a positive or negative FISH result mean?
A positive result indicates Trisomy 21 with over 99% certainty, while a negative result rules out the common aneuploidy but may still require a full karyotype to exclude other chromosomal rearrangements. All results should be interpreted alongside your obstetrician’s ultrasound findings and genetic counseling.
تعني النتيجة الإيجابية وجود تثلث الصبغي 21 بنسبة يقين تزيد عن 99%، بينما تستبعد النتيجة السلبية هذا الاختلال الصبغي الشائع ولكنها قد تستلزم تحليل النمط النووي الكامل، ويجب تفسير النتائج دائماً مع الطبيب المختص.
🔒 Regulatory Compliance: This service adheres to Federal Decree-Law No. 41 of 2024 (Art. 87), UAE PDPL (Federal Data Privacy), and the CDS Law 2026 for minors. Laboratory operations are ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139), DHA/MOHAP standardised.
📋 2026 ICD‑10‑CM Codes: Q90.9 (Down syndrome, unspecified), Q90.0 (Trisomy 21, nonmosaicism), Z36.0 (Encounter for antenatal screening for chromosomal anomalies). LOINC: 53177-3 (Chromosome 21 aneuploidy in Amniotic fluid by FISH).
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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