Test Price
2,500 AEDโ Home Collection Available
FISH for Multiple Myeloma with CD138 Positive Selection (Bone Marrow) in UAE | 2500 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Sample Collection: Hospital Extraction Only โ Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The FISH test for Multiple Myeloma with CD138 positive selection is a high-precision cytogenetic assay that identifies critical chromosomal abnormalities (e.g., del(17p), t(4;14)) in plasma cells to guide prognosis and therapy. This test enriches malignant plasma cells to over 95% purity via immunomagnetic CD138 selection, significantly increasing detection sensitivity for low-level chromosomal abnormalities that may be missed in unsorted bone marrow samples.
| Parameter | Our Test (FISH with CD138+ Selection) | Standard FISH |
|---|---|---|
| Plasma Cell Purity | >95% via immunomagnetic CD138 enrichment | Variable; often <10% |
| Detection Sensitivity | Identifies abnormalities in as few as 1% of cells | May miss low-level clones |
| Turnaround Time | 4 Working Days | 5โ7 Working Days (typical) |
| Cost | 2500 AED | ~1800โ2000 AED |
Physician Insight & Safety Protocols
โAs a Specialist Diagnostic Radiology, I emphasize that a positive FISH result must be interpreted within the full clinical picture, including bone marrow biopsy and serum protein electrophoresis. While these genetic markers refine risk stratification, they do not replace the need for comprehensive staging. I strongly advise against modifying any prescribed therapy based solely on this report without consulting your hematologist.โ
โ Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
Advisory Notice
โ ๏ธ Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients with active coagulopathy or platelet count <30,000/ยตL should not undergo bone marrow aspiration without prior medical clearance.
- Exclusion: Severe allergy to local anesthetics must be disclosed.
- ER Red Flag: Seek emergency care if you experience excessive bleeding at the aspiration site, fever >38.5ยฐC, or signs of infection within 48 hours.
Patient FAQ & Clinical Guidance
1. What does the FISH test for multiple myeloma detect?
This FISH detects specific chromosomal abnormalities in CD138-enriched plasma cells, including deletions of 17p, translocations t(4;14), t(14;16), and gain of 1q, which are critical for risk stratification and treatment decisions in multiple myeloma. These genetic markers help your oncologist determine prognosis and tailor therapy.
2. Why is CD138 positive selection necessary for accurate FISH results?
CD138 positive immunomagnetic selection enriches malignant plasma cells to over 95% purity, significantly increasing the detection sensitivity of low-level chromosomal abnormalities that may be missed in unsorted bone marrow samples. This technique ensures that even minor clones are identified, providing a more reliable risk profile.
3. How should I prepare for the bone marrow aspiration?
You will need to sign a consent form, avoid anticoagulant medications as advised by your doctor, and ensure the Chromosome & FISH analysis Requisition Form (Form 17) is completed. The procedure is typically performed on the hip bone under local anesthesia, and you should arrange for someone to assist you afterward.
UAE Regulatory & Data Privacy Adherence
- ISO 9001:2015 Certified โ Certificate No. INT/EGQ/2509DA/3139
- Compliant with Federal Decree-Law No. 4 of 2016 on Medical Liability
- Adherence to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields
- Fully aligned with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL)
- DHA Licensed Facility No. 1143
Clinical & Logistical Metadata
| Test Name | FISH for Multiple Myeloma with CD138 Positive Selection (Bone Marrow) |
| Price (AED) | 2500 AED |
| Turnaround Time | 4 Working Days |
| Sample Type / Matrix | Bone Marrow Aspirate (Hospital Extraction Only โ Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.) |
| Methodology Used | Fluorescence In Situ Hybridization (FISH) with immunomagnetic CD138 positive selection |
| ICD-10-CM Code | C90.0 |
| LOINC Code | 97918-9 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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