Test Price
1,200 AED✅ Home Collection Available
FISH BCL6 (3q27) Gene Rearrangement – Dubai, UAE | 1200 AED
Executive Summary & Core Metrics
Test: FISH BCL6 (3q27) Gene Rearrangement
Price: 1,200 AED
Turnaround Time: 7–8 Business Days
Sample Type: Tissue (Fresh or FFPE tumour biopsy) – Hospital extraction only; no home phlebotomy available.
Methodology: Dual‑Color Fluorescence In Situ Hybridization (FISH) – ISO 9001:2015 accredited.
Clinical Guidance: Telephonic post‑test interpretation by a consultant medical geneticist.
Accuracy: 99.9% diagnostic sensitivity for BCL6 break‑apart rearrangements.
Indications: Diffuse large B‑cell lymphoma, follicular lymphoma, and other mature B‑cell neoplasms.
Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Corporate Lab: DNA Labs UAE
Test Overview & Methodology
The FISH BCL6 (3q27) gene rearrangement test employs break‑apart fluorescent probes to detect structural rearrangements involving the BCL6 locus at chromosome 3q27. This genetic alteration is a key prognostic and diagnostic marker in aggressive B‑cell lymphomas, particularly diffuse large B‑cell lymphoma (DLBCL) and follicular lymphoma. Detection of a BCL6 rearrangement refines lymphoma classification according to the WHO‑HAEM5 criteria and can guide targeted therapy decisions.
The test is performed on formalin‑fixed paraffin‑embedded (FFPE) tissue or fresh tumour biopsy using dual‑color FISH methodology under ISO 9001:2015 quality standards. Turnaround time is 7–8 business days from sample receipt, including probe hybridization, fluorescence microscopy analysis, and expert cytogenomic interpretation.
| Feature | FISH BCL6 (Our Test) | NGS Panel / Direct Sequencing |
|---|---|---|
| Precision for Structural Variants | High‑resolution break‑apart probe; detects 100% of common BCL6 rearrangements | Detects SNVs/indels but may miss large structural rearrangements |
| Methodology | Dual‑Color FISH (ISO 9001:2015) | NGS (panel‑based) |
| Turnaround Time | 7–8 Business Days | 10–14 Business Days |
Physician Insight & Safety Protocols
“The FISH BCL6 rearrangement result must be interpreted in the full context of histopathology, immunophenotype, and clinical presentation. A positive rearrangement confirms the presence of a BCL6 alteration, which refines lymphoma classification and may guide targeted therapy. This test is not a standalone diagnostic and should be correlated with other laboratory and imaging findings.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Safety Information
⚠️ Important Clinical Advisory
Do not discontinue prescribed medication without consulting your treating physician. This FISH test is intended for diagnostic and prognostic purposes only and does not replace a comprehensive oncology consultation. If you experience sudden worsening of symptoms such as severe pain, fever, or neurological deficits, seek immediate emergency care.
Exclusion Criteria & Emergency Guidance
- Active uncontrolled bleeding or hemodynamic instability — seek immediate emergency attention.
- Patients under 18 years without informed parental/guardian consent as per UAE regulations.
- Tumour tissue must be obtained via biopsy under controlled medical settings; this test is not performed on liquid biopsy samples.
- A valid doctor’s prescription is required. Exceptions are not applicable for this test; contact our support team for assistance.
- If you experience sudden worsening of symptoms (e.g., severe pain, high fever, neurological signs), bypass the lab and visit the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. How accurate is the FISH BCL6 gene rearrangement test for lymphoma diagnosis?
The test offers a diagnostic sensitivity of 99.9% for detecting BCL6 break‑apart rearrangements in tumour tissue. It provides critical information for classifying aggressive B‑cell lymphomas and guiding personalized therapy under the latest WHO‑HAEM5 criteria. Results should always be interpreted alongside histopathology and immunophenotyping.
2. Do I need a doctor’s prescription for this test?
Yes, a valid doctor’s prescription is mandatory for this test. The prescription requirement is strictly applied; no exceptions are made. Please contact our support team if you need assistance with documentation.
3. How soon can I receive my results, and what does the turnaround time include?
Results are available within 7–8 business days after the sample arrives at the laboratory. This period includes probe hybridization, fluorescence microscopy analysis, and expert cytogenomic interpretation as per ISO 9001:2015 quality standards.
UAE Regulatory & Data Privacy Adherence
Your health data is protected under Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. DNA Labs UAE holds DHA Facility License No. 1143 and operates in full compliance with all UAE federal healthcare regulations. All clinical testing and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability. Your privacy is our priority.
Clinical & Logistical Metadata
| Test Name | FISH BCL6 (3q27) Gene Rearrangement |
| Price (AED) | 1,200 AED |
| Turnaround Time | 7–8 Business Days |
| Sample Type / Matrix | Tissue (Fresh biopsy or FFPE tumour block) – Hospital Extraction Only; mobile home phlebotomy is disabled for safety. |
| Methodology Used | Dual‑Color Fluorescence In Situ Hybridization (FISH) – ISO 9001:2015 accredited. |
| ICD-10-CM Code | C83.3 (Diffuse large B‑cell lymphoma) |
| LOINC Code | 33556-8 (BCL6 gene rearrangement by FISH) |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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