Test Price
800 AED✅ Home Collection Available
BCL6 (3q27) Gene Rearrangement Test in UAE | 800 AED | DHA Licensed
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity via ISO 15189 accredited FISH processing. Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. Free post-test telephonic clinical guidance. Direct insurance verification via WhatsApp +971 54 548 8731.
Price: 800 AED | Turnaround Time: 4 working days | Methodology: FISH | Sample Type: Bone marrow aspirate or tissue biopsy (Hospital Extraction Only)
Test Overview & Methodology
The BCL6 (3q27) Gene Rearrangement Test by FISH is the definitive molecular cytogenetic assay for identifying translocations involving the 3q27 locus. It is essential in the diagnostic workup of aggressive B-cell lymphomas, especially diffuse large B-cell lymphoma (DLBCL).
| Feature | Our Test (FISH) | PCR-based BCL6 Panel |
|---|---|---|
| Precision | Direct visualization of rearrangement in intact nuclei | May miss large, novel, or complex rearrangements |
| Turnaround Time | 4 working days | 5–7 working days |
| Methodology | Fluorescence In-Situ Hybridization (gold standard) | Break-apart PCR / NGS fusion panel |
Physician Insight & Safety Protocols
“BCL6 rearrangement is a key prognostic marker in diffuse large B-cell lymphoma. It helps distinguish germinal center B-cell subtype, which is associated with a more favorable outcome. This test must be correlated with immunohistochemistry (CD10, BCL6, MUM1) and full clinical history. Our genetics team is dedicated to providing clear, compassionate counselling throughout the diagnostic process.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA ID: 9294403
Advisory: Pre-Test Medication and Preparation
Do not discontinue prescribed medication without consulting your doctor. A completed Chromosome & FISH Requisition Form (Form 17) is mandatory. Sample must be maintained at 18–22°C. Do not freeze.
Exclusion Criteria and Red Flags
Not suitable for patients with active sepsis, INR >2.5, or ongoing therapeutic anticoagulation. Seek immediate medical care if you develop fever >38.3°C, uncontrolled bleeding, or severe pain after sample collection.
Patient FAQ & Clinical Guidance
1. What is the BCL6 (3q27) Gene Rearrangement Test?
The BCL6 gene rearrangement by FISH detects chromosomal translocations involving the 3q27 locus, which are hallmark aberrations in certain aggressive lymphomas. It helps hematopathologists confirm a diagnosis of diffuse large B-cell lymphoma, follicular lymphoma, or high-grade B-cell lymphoma when morphology alone is inconclusive.
2. How should I prepare for the sample collection?
No dietary restrictions are required, but a completed Chromosome & FISH Requisition Form (Form 17) must accompany the specimen. Tissue biopsy or bone marrow aspiration is performed under local anesthesia; follow your physician’s instructions regarding blood-thinning medications.
3. What does a positive result mean and what should I do next?
A positive BCL6 rearrangement indicates a clonal lymphoid population with 3q27 translocation, consistent with a germinal center B-cell lymphoma. This finding must be integrated into a full diagnostic report by your hematologist, who will recommend further staging (PET-CT, bone marrow biopsy) and personalized treatment.
UAE Regulatory & Data Privacy Adherence
- Licensed by DHA (Facility License: 1143).
- Testing complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Minor sample collection respects Federal Decree-Law No. 4 of 2016 on Medical Liability with mandatory guardian consent.
- Accredited under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
- Corporate entity: DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | BCL6 (3q27) Gene Rearrangement Test (FISH) |
| Price (AED) | 800 |
| Turnaround Time | 4 working days |
| Sample Type / Matrix | Bone marrow aspirate or tissue biopsy (Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.) |
| Methodology Used | Fluorescence In-Situ Hybridization (FISH) |
| ICD-10-CM Code | C83.3 |
| LOINC Code | 68299-1 |
| DHA Facility License & Laboratory Address | DHA Facility License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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