Test Price
2,800 AEDโ Home Collection Available
APOA2 Gene Familial Hypercholesterolemia Modifier Genetic Test in UAE โ 2800 AED โ DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (available daily 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance with result interpretation by Consultant Medical Genetics.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced genetic test analyzes the APOA2 gene for variants that modify the severity of familial hypercholesterolemia (FH). Using next-generation sequencing (NGS) technology, the test identifies rare modifier alleles that can accelerate atherosclerosis and elevate cardiovascular risk, enabling precise risk stratification and personalised lipid management.
| Feature | Our APOA2 Modifier NGS Test | Standard FH Gene Panel |
|---|---|---|
| Precision | 99.9% Diagnostic Sensitivity (ISO Certified) | ~95% Sensitivity (Sanger Sequencing) |
| Method | NGS (Illumina NovaSeq) โ covers APOA2 modifier | Sanger Sequencing โ limited to LDLR, APOB, PCSK9 genes |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Clinical Insight | Personalized FH severity scoring & modifier risk | Basic mutation detection, no modifier info |
Physician Insight & Safety Protocols
โWhile this APOA2 modifier test provides critical molecular insight into the aggressiveness of familial hypercholesterolemia, it must be correlated with your complete lipid profile, family history, and physical examination. Do not make any changes to your statin or lipid-lowering therapy without consulting a cardiologist or lipid specialist. Genetic results should always be interpreted in the context of clinical guidelines.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue prescribed medication (e.g., statins, ezetimibe) without consulting your doctor. This genetic test does not replace immediate clinical management of high cholesterol or acute cardiac symptoms. If you experience sudden chest pain, shortness of breath, or palpitations, seek emergency care immediately.
Exclusion Criteria & Red Flags
- Acute infection requiring hospitalization or antibiotic therapy in the last 72 hours.
- Recent blood transfusion (within 2 weeks) may affect DNA quality.
- Unable to provide informed consent or unaccompanied minors (parental/guardian consent required for individuals under 18).
This test is not a substitute for acute cardiovascular evaluation. In case of emergency, call 999 or proceed to the nearest emergency department.
Patient FAQ & Clinical Guidance
1. What does the APOA2 gene modifier test reveal about my cholesterol risk?
This test identifies rare APOA2 gene variants that can worsen familial hypercholesterolemia, enabling earlier and more precise interventions to lower cardiovascular risk. The results provide a modifier risk score that complements standard FH gene panel findings.
2. How is the sample collected and is home service available?
A certified phlebotomist collects a small blood sample (peripheral whole blood) at your home between 8 AM and 11 PM, using ISO-certified cold-chain transport to preserve DNA integrity. The VIP Mobile Phlebotomy service is available across Dubai and select emirates.
3. Will my insurance cover this genetic test?
We provide direct insurance billing verification via WhatsApp at +971 54 548 8731. Many UAE insurers cover medically indicated FH genetic testing when prescribed by a specialist and following DHA guidelines. Please contact us to confirm your coverage.
4. How long does it take to get results and how are they delivered?
The turnaround time is 3 to 4 weeks from sample collection. Results are delivered via secure electronic report (PDF) and include a telephone consultation with our Consultant Medical Genetics for interpretation and clinical recommendations.
5. What are the legal and safety considerations?
All genetic testing is performed under the supervision of DHA-licensed physicians and in compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning health ICT use. Informed consent is mandatory before sample collection.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance
This service operates in full compliance with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Federal Decree-Law No. 4 of 2016 on Medical Liability (informed consent and clinical safety).
- Dubai Healthcare City standards and DHA licensing requirements.
Laboratory licensed under DHA Facility License No. 1143. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). All genetic counselling and testing are conducted by DHA-licensed professionals.
Clinical & Logistical Metadata
| Test Name | APOA2 Gene Familial Hypercholesterolemia Modifier Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA tube) โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection |
| Methodology Used | Next-Generation Sequencing (NGS) โ Illumina NovaSeq |
| ICD-10-CM Code | E78.01 (Familial hypercholesterolemia) |
| LOINC Code | 21636-8 (DNA analysis) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians