EWSR1 gene Ewing’s sarcoma Test – DNA Labs UAE
Test Name: EWSR1 gene Ewing’s sarcoma Test
Components: Paraffin embedded tissue blocks
Price: 1500.0 AED
Sample Condition: Tumor tissue
Report Delivery: 7-8 days
Method: FISH
Test type: Genetics
Doctor: Oncology
Test Department:
Pre Test Information: EWSR1 gene (Ewing’s sarcoma) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Test Details
The EWSR1 gene, also known as Ewing’s sarcoma breakpoint region 1, is a gene that plays a role in the development of Ewing’s sarcoma, a rare type of bone and soft tissue cancer. Ewing’s sarcoma is characterized by a chromosomal translocation that involves the fusion of the EWSR1 gene with a partner gene, most commonly the FLI1 gene.
This fusion gene produces an abnormal protein that is thought to contribute to the development of cancer. The EWSR1 gene is located on chromosome 22 and encodes a protein called RNA-binding protein EWS. This protein is involved in various cellular processes, including gene expression regulation, RNA splicing, and DNA repair.
The fusion of EWSR1 with a partner gene in Ewing’s sarcoma disrupts the normal function of the EWSR1 protein and leads to the formation of cancerous cells. Understanding the role of the EWSR1 gene in Ewing’s sarcoma has helped in the development of targeted therapies for this type of cancer.
Targeting the abnormal protein produced by the fusion gene has shown promise in treating Ewing’s sarcoma and improving patient outcomes.
Test Name | EWSR1 gene Ewing’s sarcoma Test |
---|---|
Components | Paraffin embedded tissue blocks |
Price | 1500.0 AED |
Sample Condition | Tumor tissue |
Report Delivery | 7-8 days |
Method | FISH |
Test type | Genetics |
Doctor | Oncology |
Test Department: | |
Pre Test Information | EWSR1 gene (Ewing’s sarcoma) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
Test Details |
The EWSR1 gene, also known as Ewing’s sarcoma breakpoint region 1, is a gene that plays a role in the development of Ewing’s sarcoma, a rare type of bone and soft tissue cancer. Ewing’s sarcoma is characterized by a chromosomal translocation that involves the fusion of the EWSR1 gene with a partner gene, most commonly the FLI1 gene. This fusion gene produces an abnormal protein that is thought to contribute to the development of cancer. The EWSR1 gene is located on chromosome 22 and encodes a protein called RNA-binding protein EWS. This protein is involved in various cellular processes, including gene expression regulation, RNA splicing, and DNA repair. The fusion of EWSR1 with a partner gene in Ewing’s sarcoma disrupts the normal function of the EWSR1 protein and leads to the formation of cancerous cells. Understanding the role of the EWSR1 gene in Ewing’s sarcoma has helped in the development of targeted therapies for this type of cancer. Targeting the abnormal protein produced by the fusion gene has shown promise in treating Ewing’s sarcoma and improving patient outcomes. |