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Oncomine Tumor Mutation Burden TMB and Microsatellite Instability MSI Test

10,500 د.إ

-25%

The Oncomine Tumor Mutation Burden (TMB) and Microsatellite Instability (MSI) Test is a comprehensive diagnostic tool offered by DNA Labs UAE, designed to assess two critical biomarkers in cancer patients: Tumor Mutation Burden (TMB) and Microsatellite Instability (MSI). This test is pivotal in the realm of precision medicine, as it helps in identifying the genetic alterations within tumors, thereby guiding oncologists in tailoring the most effective treatment strategies for individual patients.

TMB is a measure of the number of mutations within a tumor’s DNA, which can be indicative of how well a patient might respond to certain immunotherapies. A high TMB can suggest a tumor is more likely to respond to these treatments. On the other hand, MSI is a condition that occurs due to the failure of the DNA mismatch repair system, leading to increased mutations. It is particularly prevalent in certain types of cancers, such as colorectal cancer, and its presence can also influence treatment decisions, including the use of immunotherapy.

The test is conducted through a sophisticated genomic sequencing process, analyzing a comprehensive panel of genes associated with various cancers to determine the TMB and MSI status. The cost of the test at DNA Labs UAE is 10,500 AED, reflecting the advanced technology and expertise required to perform this intricate analysis. By providing a detailed genetic profile of a patient’s tumor, the Oncomine TMB and MSI Test plays a crucial role in advancing personalized cancer care, offering hope for more effective and targeted treatment options.

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Oncomine Tumor Mutation Burden (TMB) and Microsatellite Instability (MSI) Test

Test Name: Oncomine Tumor mutation burden (TMB) and Microsatellite Instability (MSI) Test

Components: Paraffin embedded tissue blocks + EDTA Vacutainer (3 ml)

Price: 10500.0 AED

Sample Condition: Tumor tissue + Peripheral Blood

Report Delivery: 2-3 weeks

Method: NGS + Sanger Sequencing

Test Type: Genetics

Doctor: Oncology

Test Department:

Pre Test Information: Oncomine Tumor mutation burden (TMB) + Microsatellite Instability (MSI) Test requires a doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details: Oncomine Tumor mutation burden (TMB) + Microsatellite Instability (MSI) Test is a test that measures the amount of mutations in a tumor and the level of microsatellite instability. TMB is the number of mutations per megabase of DNA in a tumor, while MSI is the instability of microsatellites, which are short repeated sequences of DNA that are prone to errors during DNA replication. High TMB and MSI levels are associated with increased response to immune checkpoint inhibitors, which are drugs that stimulate the immune system to attack cancer cells. The Oncomine TMB + MSI test can help identify patients who may benefit from immunotherapy treatment and is used in the diagnosis and treatment of various cancers.

Test Name Oncomine Tumor mutation burden TMB and Microsatellite Instability MSI Test
Components Paraffin embedded tissue blocks + EDTA Vacutainer (3 ml)
Price 10500.0 AED
Sample Condition Tumor tissue + Peripheral Blood
Report Delivery 2-3 weeks
Method NGS + Sanger Sequencing
Test type Genetics
Doctor Oncology
Test Department:
Pre Test Information Oncomine Tumor mutation burden TMB] + Microsatellite Instability (MSI) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

Oncomine Tumor mutation burden (TMB) + Microsatellite Instability (MSI) is a test that measures the amount of mutations in a tumor and the level of microsatellite instability. TMB is the number of mutations per megabase of DNA in a tumor, while MSI is the instability of microsatellites, which are short repeated sequences of DNA that are prone to errors during DNA replication. High TMB and MSI levels are associated with increased response to immune checkpoint inhibitors, which are drugs that stimulate the immune system to attack cancer cells. The Oncomine TMB + MSI test can help identify patients who may benefit from immunotherapy treatment and is used in the diagnosis and treatment of various cancers.