GNAL (DYT25) Genetic Test in UAE | 2800 AED | DNA Labs UAE

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Next‑Generation Sequencing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Telephonic Post‑Test Clinical Guidance for result interpretation.
Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

The GNAL (DYT25) Genetic Test screens for pathogenic variants in the GNAL gene associated with isolated dystonia. It provides definitive molecular confirmation for clinical diagnosis, personalized management, and family risk assessment.

Feature	Our Test (GNAL NGS)	Closest Alternative (Single‑Gene Sequencing)
Precision	99.9% Diagnostic Sensitivity, full gene coverage	Limited to targeted exons, may miss deep intronic variants
Methodology	Next‑Generation Sequencing (NGS) with CNV analysis	Sanger sequencing (no CNV detection)
Turnaround	3–4 Weeks	6–8 Weeks
Sample	Whole Blood, Extracted DNA, or FTA Card (one drop blood)	Whole Blood only

Physician Insight & Safety Protocols

“This test uncovers the molecular basis of your dystonia with high certainty, but it is only one piece of the diagnostic puzzle. I encourage you to interpret the result alongside your full clinical picture, and never stop or adjust any prescribed medication without consulting your treating physician.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory: Medication Continuation

Do not discontinue prescribed medication without consulting your doctor. Genetic test results inform, not replace, ongoing neurological care.

Exclusion Criteria & Red Flags

Exclusion: Individuals unable to provide a blood sample or informed consent.
Exclusion: Samples that do not meet pre‑analytical stability (e.g., lipemic, clotted).
Red Flag Symptoms: If you experience acute worsening of dystonia, breathing difficulty, or speech loss, seek emergency care immediately; do not wait for test results.

Patient FAQ & Clinical Guidance

1. What is the GNAL DYT25 test and why is it recommended?

It identifies disease‑causing mutations in the GNAL gene to confirm isolated dystonia, guide treatment, and clarify hereditary risk for family members. Early genetic diagnosis can prevent unnecessary investigations and direct targeted therapies.

2. How is the sample collected and how long do results take?

A simple blood draw, extracted DNA, or a finger‑prick blood spot on an FTA card is collected at home or in clinic; results are ready in 3 to 4 weeks. Our VIP mobile phlebotomy ensures strict cold‑chain preservation from your doorstep to the ISO‑accredited lab.

3. Is genetic counselling required before and after this test?

Yes, pre‑test genetic counselling is mandatory to review family history and obtain informed consent, while post‑counselling explains the result’s impact on your health and your relatives’ risks. Our clinical team provides a dedicated counselling session prior to sample collection.

UAE Regulatory & Data Privacy Adherence

DNA Labs UAE complies fully with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is processed under strict confidentiality, with patient consent obtained prior to testing. Clinical safety and patient rights are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.

Clinical & Logistical Metadata

Test Name	GNAL (DYT25) Genetic Test
Price (AED)	2,800 AED
Turnaround Time	3–4 Weeks
Sample Type / Matrix	Whole Blood, Extracted DNA, or FTA Card
Methodology Used	Next‑Generation Sequencing (NGS) with CNV analysis
ICD-10-CM Code	G24.1
LOINC Code	48000-4
DHA Facility License & Laboratory Address Invariants	DHA License No. 1143 \| DNA Labs UAE \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE