AKT2 Gene Diabetes Mellitus, Noninsulin-Dependent, Genetic Test in UAE | AED 2800

Executive Summary & Core Metrics

Core Metrics & Guarantees

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Telephonic Post–Test Clinical Guidance with a DHA-licensed genetic counselor.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The AKT2 Gene NGS Test screens for pathogenic variants in the AKT2 gene associated with monogenic noninsulin-dependent diabetes, enabling precise diagnosis and personalized management. This targeted sequencing approach provides high-depth coverage of the entire AKT2 coding region and splice sites.

Feature	Our Test	Closest Alternative (Whole Exome)
Methodology	Targeted NGS (high-depth AKT2 gene sequencing)	Whole Exome Sequencing (lower coverage per gene)
Turnaround Time	3 – 4 Weeks	6 – 8 Weeks
Diagnostic Yield	>99.9% sensitivity for AKT2 variants	Variable; may miss deep intronic variants
Cost	AED 2800	Typically AED 5000+

Physician Insight & Safety Protocols

“If you receive a genetic result indicating a predisposition, consider it a powerful tool for preventive care rather than a definitive diagnosis. Collaborating closely with your endocrinologist and our genetic counseling team will ensure the best management path for your unique situation.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

⚠️ Medication Advisory

Never stop, start, or modify your diabetes medications without explicit instructions from your treating physician. Genetic test results may influence future therapy but should not prompt immediate self-directed changes.

Safety & Exclusion Criteria

Exclusions: Individuals under 18 without legal guardian consent (Federal Decree-Law No. 4 of 2016 on Medical Liability), severe hemophilia or active anticoagulation (risk of excessive bleeding), inability to provide informed consent.
ER Red Flags: If you experience signs of severe hypoglycemia (confusion, seizures, loss of consciousness) or diabetic ketoacidosis (nausea, vomiting, abdominal pain, fruity breath), seek immediate emergency care.

Pre‑Test Information

A genetic counseling session is required before sample collection to draw a pedigree chart of family members affected with noninsulin‑dependent diabetes. This step ensures accurate interpretation of your results and is fully supported by our DHA‑licensed genetic counselors. Sample required: Blood (venous draw) collected by our certified phlebotomist. No fasting is necessary unless otherwise advised.

Patient FAQ & Clinical Guidance

1. What is the AKT2 gene and its role in noninsulin‑dependent diabetes?

Snippet: This test screens for pathogenic variants in the AKT2 gene, which encodes a critical insulin signaling protein, identifying monogenic diabetes that often mimics type 2 diabetes. The result can distinguish whether your diabetes has a strong genetic cause requiring tailored therapy.

2. Who should consider taking this genetic test?

Snippet: Individuals with a strong family history of early‑onset diabetes, unexplained non‑autoimmune diabetes, or syndromic features suggestive of monogenic diabetes should consider this targeted genetic analysis. It is particularly useful for patients diagnosed before age 40 who do not fit typical type 2 profiles.

3. How long does it take to receive results and how are they interpreted?

Snippet: Results are typically delivered within 3 to 4 weeks, accompanied by a comprehensive report interpreted by a certified genetic counselor and your referring specialist. The report includes variant classification according to ACMG guidelines and personalized management recommendations.

UAE Regulatory & Data Privacy Adherence

Data Privacy & Legal Compliance

Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): All personal data collected during the testing process is processed in strict accordance with PDPL requirements, ensuring confidentiality, integrity, and lawful handling.
Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: Our digital infrastructure and telehealth services comply fully with this law governing health information systems.
Federal Decree-Law No. 4 of 2016 on Medical Liability: Patient consent and clinical safety protocols are aligned with this law, ensuring informed decision-making and medical accountability.

Clinical & Logistical Metadata

Test Name	AKT2 Gene Diabetes Mellitus, Noninsulin-Dependent, Genetic Test
Price (AED)	AED 2800
Turnaround Time	3 – 4 Weeks
Sample Type / Matrix	Whole Blood (venous draw) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM)
Methodology Used	Targeted Next-Generation Sequencing (NGS) – High-depth AKT2 gene sequencing
ICD-10-CM Code	E11.9, Z13.1, Z15.81
LOINC Code	51969-4
DHA Facility License & Laboratory Address	DHA Facility License: 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE