Test Price
2,800 AEDโ Home Collection Available
DGKE Gene Nephrotic Syndrome Type 7 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Diagnostic Sensitivity โ 99.9% via Next-Generation Sequencing with ISO 9001:2015 certified processing.
- VIP Mobile Phlebotomy โ Temperature-controlled cold-chain home collection available daily 8 AM โ 11 PM.
- Physician TeleGuidance โ Post-test clinical interpretation by DHA-licensed genetics consultant.
- Insurance Verification โ Direct billing and coverage check via WhatsApp at +971 54 548 8731.
Precise genetic screening for nephrotic syndrome type 7, combining advanced genomics with compliant, patient-centered logistics.
Test Overview & Methodology
The DGKE Gene NGS Test utilizes comprehensive Next-Generation Sequencing to detect pathogenic variants in the DGKE gene, providing definitive diagnosis of nephrotic syndrome type 7 (NPHS7) with near-complete diagnostic accuracy. Full exonic coverage ensures detection of deep intronic and copy-number variants missed by conventional methods.
| Parameter | Our Test (DGKE NGS) | Single-Gene Sanger Sequencing |
|---|---|---|
| Methodology | Next-Generation Sequencing (full gene coverage) | Sanger sequencing (limited to known hotspots) |
| Detection Rate | >99.9% for all pathogenic variants | ~85% (misses deep intronic/copy-number changes) |
| Turnaround Time | 3โ4 Weeks | 4โ6 Weeks |
| Sample | Whole Blood, Extracted DNA, or FTA Card (single drop) | Whole Blood only |
Physician Insight & Safety Protocols
โGenetic test results for nephrotic syndrome type 7 must be interpreted within the full clinical context, including renal biopsy findings, family pedigree, and a pediatric nephrology evaluation. A pathogenic DGKE variant is strongly associated with early-onset disease, but correlation with age and renal histology is essential. Our service ensures comprehensive pre-test genetic counselling and post-test multidisciplinary discussion.โ โ Ms. Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Guidelines
Do not discontinue or adjust any prescribed medication without consulting your nephrologist. Genetic testing is an adjunct, not a replacement, for ongoing clinical management. Results should be shared with your treating physician.
Exclusion Criteria & Emergency Red Flags
- Acute febrile illness or active infection โ reschedule blood draw after complete recovery.
- Recent blood transfusion (within 2 weeks) โ may interfere with DNA extraction; consult the lab prior to sampling.
- Minors without parental/guardian consent as per Federal Decree-Law No. 4 of 2016 on Medical Liability โ mandatory documented informed consent required.
- Seek emergency care immediately if you experience severe edema, shortness of breath, or hypertensive crisis; genetic testing is not appropriate during acute nephrotic crisis.
Patient FAQ & Clinical Guidance
1. What is the purpose of the DGKE Gene NGS Test?
This test identifies pathogenic variants in the DGKE gene to confirm a diagnosis of nephrotic syndrome type 7 (NPHS7) and enables predictive testing for at-risk family members.
2. How is the sample collected for this genetic analysis?
Sample collection involves a simple blood draw or a finger-prick FTA card. Both methods are available via our VIP Mobile Phlebotomy service with temperature-controlled cold-chain logistics, daily from 8 AM to 11 PM.
3. Why choose this test over standard genetic testing?
Our test employs Next-Generation Sequencing covering all coding and non-coding regions of DGKE, achieving >99.9% sensitivity and including detailed variant interpretation with ACMG guidelines. Reports are DHA-approved and include pharmacogenomic notations.
UAE Regulatory & Data Privacy Adherence
Compliance Framework
This genetic testing service operates under the strict legal and regulatory framework of the United Arab Emirates:
- Data protection governed by Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health information security in accordance with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Patient consent and clinical safety under Federal Decree-Law No. 4 of 2016 on Medical Liability.
- All genetic data is encrypted and stored in UAE-based servers with access restricted to authorized personnel only.
Clinical & Logistical Metadata
| Test Name | DGKE Gene โ Nephrotic Syndrome Type 7 (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3 โ 4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card (finger-prick) |
| Methodology Used | Next-Generation Sequencing (full gene coverage) |
| ICD-10-CM Code | N04.9 |
| LOINC Code | 81247-9 |
| DHA Facility License & Laboratory Address | DHA License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians