Test Price
950 AED✅ Home Collection Available
Desmoglein 1 & 3 Antibody Test in UAE | 950 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary – Clinical Confidence, Local Trust
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed specialists.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Desmoglein 1 & 3 Antibody Test is a specialized immunofluorescence assay that detects pathogenic autoantibodies against desmoglein proteins – the critical adhesive components of the skin and mucous membranes. This test enables definitive differentiation between pemphigus vulgaris and pemphigus foliaceus, serving as the gold-standard serological marker for diagnosing and monitoring autoimmune blistering disorders.
| Feature | Our Test – Desmoglein IFA | Closest Alternative – Desmoglein ELISA |
|---|---|---|
| Precision | End-point titration + substrate pattern by expert dermatopathologist | Semi-quantitative OD values; may miss non-IgG4 subtypes |
| Method | Indirect Immunofluorescence (IFA) on primate esophagus & salt-split skin | ELISA with recombinant DSG1/DSG3 |
| Speed | Same-day report by 6 PM (sample Tue/Fri by 9 AM) | Often 1–3 working days |
Physician Insight & Safety Protocols
"Dear patient, while this test is a powerful tool for diagnosing autoimmune blistering diseases, a positive result must always be interpreted alongside your clinical picture and skin biopsy findings. Never attempt to self-adjust immunosuppressive medications; abrupt discontinuation can trigger a severe, potentially dangerous flare. Our team is here to guide you every step."
— Dr. Ajay Singh, General Practitioner | DHA Registration ID: 36234132
⚠️ Safety Exclusion Criteria & Emergency Red Flags
- Active infection or open wound at the venipuncture site.
- Known severe coagulopathy (e.g., hemophilia, high INR).
- Severe anemia (Hb < 7 g/dL) without physician clearance.
- Current acute febrile illness or systemic infection.
🚨 Seek immediate medical attention if you experience:
- Sudden, widespread blistering with fever or chills.
- Difficulty swallowing or breathing due to oral/throat involvement.
- Signs of infection: pus, warmth, red streaks around blisters.
- Uncontrolled pain or severe skin denudation.
🔴 Medication Warning
Do not discontinue prescribed medication—especially corticosteroids, rituximab, or mycophenolate—without consulting your doctor. Abrupt withdrawal can precipitate a life-threatening pemphigus flare. All medication adjustments must be supervised by your treating physician in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the Desmoglein 1 & 3 Antibody Test used for?
The Desmoglein 1 and 3 antibody test detects autoantibodies targeting desmoglein proteins critical for skin cell adhesion, aiding diagnosis of pemphigus vulgaris and foliaceus. It is the gold-standard serological marker for differentiating these autoimmune blistering disorders and monitoring disease activity over time.
2. How should I prepare for the blood draw?
Overnight fasting is preferred; please inform the phlebotomist about all medications, especially immunosuppressants or biologics, as they can influence antibody levels. A 2 mL serum sample is collected in an SST tube, shipped refrigerated or frozen according to strict cold-chain protocols.
3. When will I receive my results?
Results are reported the same day by 6 PM if your sample is collected on a Tuesday or Friday before 9 AM. Our ISO-certified laboratory processes the specimen with rapid turnaround, and a DHA-accredited specialist can provide telephonic guidance post-report.
4. How is this test different from a skin biopsy?
This blood test detects circulating autoantibodies, while a skin biopsy examines tissue directly for antibody deposition. Both tests are complementary; the serology helps confirm the specific autoantibody profile and monitor treatment response, whereas biopsy provides direct histopathological evidence.
📞 Home Collection & Support (8 AM – 11 PM, 7 days)
WhatsApp +971 54 548 8731UAE Regulatory & Data Privacy Adherence
Your data is protected under UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and all clinical testing procedures comply with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient safety and informed consent protocols strictly adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is fully licensed by the Dubai Health Authority (DHA) and our laboratory information management systems maintain the highest standards of confidentiality and data integrity.
Clinical & Logistical Metadata
| Test Name | Desmoglein 1 & 3 Antibody Test (IgG by IFA) |
| Price (AED) | 950 AED |
| Turnaround Time | Same day by 6 PM (Tuesday/Friday collection before 9 AM); next working day for other days |
| Sample Type / Matrix | Serum (SST tube, 2 mL) |
| Methodology Used | Indirect Immunofluorescence (IFA) on primate esophagus & salt-split skin |
| ICD-10-CM Code | L10.0 (Pemphigus vulgaris), L10.1 (Pemphigus foliaceus) |
| LOINC Code | 53896-8 (Desmoglein 1 Ab [Titer] in Serum) |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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