Test Price
2,800 AED✅ Home Collection Available
KRT14 Genetic Sequencing for Autosomal Recessive Epidermolysis Bullosa Simplex – 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Next Generation Sequencing (NGS).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation with DHA-licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This test sequences the entire KRT14 gene to detect pathogenic variants causing autosomal recessive epidermolysis bullosa simplex type 1 – a severe skin fragility disorder. Powered by NGS technology and interpreted under DHA guidelines, it delivers definitive diagnosis for clinical management, family counselling, and future risk assessment.
| Feature | Our KRT14 NGS Test (UAE Premium) | Closest Alternative (Sanger Sequencing, Single Gene) |
|---|---|---|
| Methodology | Next Generation Sequencing (NGS) – Full gene coverage, including deep intronic regions | Targeted Sanger sequencing – Limited to known mutation hotspots |
| Diagnostic Yield | >99% analytical sensitivity; detects novel and previously described KRT14 variants | ~85–90% for common variants only |
| Turnaround Time | 3–4 Weeks (ISO-accredited lab with DHA license 1143) | 4–6 Weeks (often sent overseas, less quality control) |
| Regulatory Compliance | Compliant with UAE Federal Decree-Law No. 45 of 2021 (PDPL) and Federal Law No. 2 of 2019; supervised by DHA-licensed physicians at DHA License 1143 | Partial or non‑compliant with local data privacy laws |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I emphasize the importance of accurate genetic diagnosis in managing epidermolysis bullosa simplex. This NGS-based test offers comprehensive coverage for informed clinical decisions and family counseling.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Notice
- All genetic testing requires a physician order and mandatory pre-test genetic counseling to discuss implications.
- Results should always be interpreted in conjunction with clinical findings by a qualified specialist.
- Do not cease any prescribed medications without consulting your healthcare provider. This test is not a substitute for emergency care.
Exclusion Criteria
- Exclusion: Active systemic infection, inability to provide adequate blood sample, or lack of mandatory pre‑test genetic counselling session.
- Emergency Red Flags: Sudden blistering with fever, difficulty swallowing or breathing, severe pain – seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What is KRT14 genetic testing, and why is it done?
This test identifies disease-causing mutations in the KRT14 gene to confirm autosomal recessive epidermolysis bullosa simplex type 1, enabling accurate diagnosis, inheritance counselling, and personalized care planning.
2. How long does it take to receive results?
Results are typically ready within 3 to 4 weeks from the date the sample arrives at our DHA‑accredited laboratory, with every case undergoing rigorous analytical and clinical validation.
3. Do I need a doctor’s referral or genetic counselling before testing?
Yes, UAE law requires a physician order for genetic testing; a pre‑ genetic counselling session is mandatory to discuss risks, benefits, and family implications before sample collection.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: This service strictly adheres to the following UAE laws:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – governing the collection, processing, and storage of personal and genetic data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – regulating digital health records and telemedicine.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – ensuring clinical safety and patient consent frameworks.
All genomic data is processed within DHA-licensed facilities (License 1143) under ISO 9001:2015 standards.
Clinical & Logistical Metadata
| Test Name | KRT14 Genetic Sequencing for Autosomal Recessive Epidermolysis Bullosa Simplex |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (5 mL in EDTA tube) |
| Methodology Used | Next Generation Sequencing (NGS) – Full gene coverage |
| ICD-10-CM Code | Q81.0 |
| LOINC Code | 81319-9 |
| DHA Facility License & Laboratory Address | DHA License: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Laboratory: DNA Labs UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians