Test Price
2,800 AED✅ Home Collection Available
MSX2 Gene Craniosynostosis Type 2 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
This advanced genetic test employs Next-Generation Sequencing (NGS) to detect pathogenic variants in the MSX2 gene associated with autosomal dominant craniosynostosis type 2. The analysis provides a definitive molecular etiology for premature suture fusion, enabling evidence-based surgical and clinical decision-making for families across the UAE. All processing occurs under ISO 9001:2015 accredited protocols (Cert: INT/EGQ/2509DA/3139) with direct billing verification available via WhatsApp at +971 54 548 8731.
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- ✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM to 11 PM).
- ✓ Clinical Guidance: Telephonic post-test result interpretation by a DHA-licensed genetic counselor.
Test Overview & Methodology
The MSX2 Gene Craniosynostosis Type 2 Genetic Test is a comprehensive molecular analysis designed to detect pathogenic variants in the MSX2 gene, which are strongly associated with autosomal dominant craniosynostosis type 2 and parietal foramina. This test is critical for differential diagnosis in dysmorphology cases presenting with premature suture fusion.
| Test Attribute | Our Test (Gold Standard) | Closest Alternative |
|---|---|---|
| Diagnostic Precision | Full MSX2 Gene Sequencing via NGS | Targeted Mutation Hotspot Analysis |
| Methodology | Next-Generation Sequencing (NGS) with Copy Number Variant detection validated by LC-MS/MS orthogonal confirmation | Sanger Sequencing (limited to single variant) |
| Speed & Clinical Utility | 3–4 Weeks TAT, includes clinical correlation report | 4–6 Weeks TAT, data-only output |
Physician Insight & Safety Protocols
A Note from Consultant Medical Genetics Lina Osama Zaki Quteineh (DHA: 9294403): "A molecular diagnosis of an MSX2 variant provides a definitive etiology for your child's craniofacial presentation, yet it is the nuanced clinical correlation with dysmorphology findings that truly guides surgical timing. Please understand this result is a powerful piece of a larger diagnostic puzzle, and I am here to connect this data to your child's personalized care pathway. We must always review these findings in the context of a complete physical examination."
Advisory – Medication Continuation
Do not discontinue or adjust any prescribed medication, including anticoagulants or anti-epileptics, without explicit consultation with your managing physician. This test requires a clinical history but does not mandate cessation of therapy.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Inability to provide adequate venous blood or DNA sample volume; active, untreated systemic infection within 48 hours of collection; lack of informed consent for genetic testing under UAE Federal Decree-Law No. 4 of 2016 on Medical Liability for minor subjects.
- Emergency Red Flags (Seek Immediate Medical Attention): Signs of raised intracranial pressure (severe projectile vomiting, sunsetting eyes, acute irritability) in the patient being tested, as these may indicate a neurosurgical emergency unrelated to test scheduling.
Patient FAQ & Clinical Guidance
1. How does this MSX2 Gene test definitively confirm a diagnosis of Craniosynostosis Type 2?
This test confirms the diagnosis by directly sequencing the entire MSX2 gene to detect known pathogenic single nucleotide variants or copy number alterations that cause autosomal dominant craniosynostosis type 2, providing a molecular etiology for the structural suture fusion observed on imaging.
2. What does the 2800 AED price include, and is home collection available for my infant?
The comprehensive package covers the ISO-certified VIP mobile phlebotomy home visit for a pain-minimized capillary or venous draw, full NGS laboratory analysis, a detailed clinical geneticist-reviewed report, and a post-telephonic guidance session to interpret the findings.
3. How does UAE Federal Law protect my child's genetic data and personal privacy?
Under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, your child's genetic data is classified as sensitive personal information requiring explicit written consent for processing, with stringent security protocols, data localization mandates, and a complete prohibition on sharing with unauthorized third parties.
UAE Regulatory & Data Privacy Adherence
Your genetic data is processed and protected under the Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. These legislative frameworks mandate explicit written consent for processing of genetic information, strict data localization within UAE sovereign infrastructure, encrypted transmission channels, and complete prohibition of unauthorized third-party data sharing. Clinical safety protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring every step from specimen collection to result disclosure meets the highest standards of patient safety and professional accountability.
Clinical & Logistical Metadata
| Test Name | MSX2 Gene Craniosynostosis Type 2 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection) |
| Methodology Used | Next-Generation Sequencing (NGS) with Copy Number Variant Detection |
| ICD-10-CM Code | Q75.0 |
| LOINC Code | 82308-3 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians