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Test Price

900 AED

✅ Home Collection Available

Properdin Factor B (C3 Proactivator) Test in UAE | DNA Labs UAE

Executive Summary & Core Metrics

  • Guaranteed Precision: 99.9% diagnostic sensitivity via ISO 9001:2015 standardized immunonephelometric assay, traceable to WHO international reference standards.
  • VIP Mobile Phlebotomy & Cold-Chain Logistics: Hospital-grade serum collection at home with temperature-controlled transport (Available daily from 8 AM to 11 PM).
  • Clinical Guidance: Complimentary post-test telephonic interpretation session with a licensed General Practitioner.
  • Insurance Verification: Direct coverage confirmation via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

The Properdin Factor B (C3 Proactivator) Test precisely quantifies the alternative complement pathway component (Factor B) to diagnose and monitor complement-mediated renal pathologies, including atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy. Quantitative immunonephelometry ensures high-specificity measurement of complement dysregulation.

Feature DNA Labs UAE ISO-Certified Test Standard Lab Alternative
Diagnostic Sensitivity 99.9% (LC-MS/MS-validated immunonephelometry) Variable; basic nephelometry often lacks standardized calibration
Methodology ISO 9001:2015 immunonephelometric assay with multi-level quality controls Nephelometry without ISO certification; limited internal QC
Turnaround Time Guaranteed 2–3 weeks post-batch cutoff (monthly cycle) Often 4–6 weeks; no fixed batch commitment or communication
Home Collection Logistics VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM–11 PM) Usually not offered or limited to basic courier without cold-chain guarantees

Physician Insight & Safety Protocols

“As a General Practitioner specializing in clinical diagnostics, I emphasize that the Properdin Factor B test must be interpreted alongside a complete clinical history, renal biopsy findings, and a full complement panel. A single abnormal value is diagnostic context, not a standalone verdict. Never self-adjust complement inhibitors or immunosuppressants without direct nephrologist consultation.”

— Dr. Ajay Singh, General Practitioner | DHA Registration ID: 36234132

Advisory & Precautions

Medication Advisory

Do not discontinue any prescribed medication, especially complement inhibitors (e.g., eculizumab) or immunosuppressants, without explicit instruction from your treating physician. Abrupt cessation can lead to severe disease flare or thrombotic microangiopathy.

Exclusion Criteria & ER Red Flags

  • Exclusion Criteria: Active severe infection, unstable vital signs, acute bleeding disorder, or inability to provide informed consent. Minors require legal guardian consent in full compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
  • Emergency Red Flags After Collection: If you experience severe dizziness, fainting, persistent bleeding at the puncture site, or signs of allergic reaction (hives, swelling, difficulty breathing), seek emergency medical care immediately.
  • Pre-Test Restriction: Serum must be separated from cells within 2 hours of collection; sample must be shipped refrigerated or frozen. A duly signed informed consent form is mandatory prior to sample collection.

Patient FAQ & Clinical Guidance

1. What is the Properdin Factor B (C3 Proactivator) test used for?

This test quantitatively measures complement Factor B levels, a key component of the alternative complement pathway. It is primarily used to aid in the diagnosis of atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy, and other complement-mediated renal disorders.

2. How should I prepare for this test?

No fasting is required. Please inform the phlebotomy team of all current medications, including over-the-counter supplements and anticoagulants, to ensure accurate result interpretation.

3. What type of sample is collected?

A standard 2 mL peripheral venous blood sample is collected in a gold-top serum separator tube (SST). Our trained phlebotomist will handle the collection at your preferred location.

4. When will I receive my results?

Samples received by the 7th of the month will have results delivered within 2 to 3 weeks. Reports are accessible via our secure online portal, followed by a free telephonic consultation to review your clinical report.

UAE Regulatory & Data Privacy Adherence

Data Privacy & Security: Your medical records and personal data are processed strictly under the framework of Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.

Clinical Safety & Consent: All diagnostic procedures and patient consent protocols strictly adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring the highest standards of patient safety and clinical governance.

Accreditations & Licensing: DNA Labs UAE operates under DHA Facility License Number 1143, with all testing conducted at our CAP-accredited laboratory facility in Dubai Healthcare City.

Clinical & Logistical Metadata

Test Name Properdin Factor B (C3 Proactivator) Test
Price (AED) 900
Turnaround Time 2 – 3 weeks (batch-dependent; monthly cycle)
Sample Type / Matrix Peripheral Serum (Gold-top SST tube, 2 mL)
Methodology Used Immunonephelometry (ISO 9001:2015 Certified)
ICD-10-CM Code D59.3, N00-N08
LOINC Code 44878-6
DHA Facility License & Laboratory Address Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | License 1143

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