Test Price
650 AEDโ Home Collection Available
Factor V Functional Test in UAE | 650 AED
Executive Summary & Core Metrics
First-Line Thrombophilia Screening with 99.9% Clinical Sensitivity
The Factor V Functional Test is an essential first-line laboratory assay for evaluating unexplained thrombophilia, recurrent venous thromboembolism, and family histories of coagulation disorders. It accurately measures coagulation Factor V activity to screen for quantitative deficiencies and qualitative Activated Protein C Resistance (APC-R), the hallmark of hereditary thrombophilia including Factor V Leiden. Performed under ISO 9001:2015 accredited processes (Cert: INT/EGQ/2509DA/3139) at DNA Labs UAE, this assay guarantees 99.9% diagnostic sensitivity. Premium logistics include hospital-grade home collection via ISO-certified cold-chain with VIP mobile phlebotomy available daily from 8 AM to 11 PM, supported by telephonic post-test clinical guidance and direct insurance billing verification.
Test Overview & Methodology
The Factor V Functional Test utilizes electromechanical clot detection to quantify Factor V activity in citrated platelet-poor plasma. This first-line functional screening tool effectively identifies quantitative deficiencies and qualitative resistance to Activated Protein C (APC). Unlike genetic PCR tests that detect specific mutations like the Factor V Leiden G1691A substitution, the functional assay provides a phenotypic assessment of the coagulation cascade, offering rapid turnaround for clinical decision-making.
| Feature | Our Factor V Functional Test | Closest Alternative (PCR-Based Factor V Leiden) |
|---|---|---|
| Methodology | Electromechanical Clot Detection (functional assay) | Real-time PCR (genetic mutation detection) |
| Diagnostic Precision | 99.9% Sensitivity for APC-R phenotype | >99% for Factor V Leiden mutation |
| Turnaround Time | Next working day | 3โ5 working days |
| Cost (AED) | 650 | 750โ900 |
| Clinical Utility | First-line screening for both deficiency & resistance | Confirmation of specific mutation only |
Physician Insight & Safety Protocols
โAs a General Practitioner coordinating first-line thrombophilia assessments, I find the Factor V Functional Test invaluable for its high sensitivity to Activated Protein C Resistance. This phenotypic assay provides crucial initial data, but results must be carefully integrated with the patientโs complete medical and family history. A detailed medication review for anticoagulant interference is mandatory before interpreting the result. Confirmatory genetic analysis for the Factor V Leiden mutation is recommended when APC-R is detected.โ
โ Dr. Ajay Singh, General Practitioner, DHA License 36234132
Medication Advisory for Assay Accuracy
Do not discontinue prescribed anticoagulants (Heparin, Warfarin, Direct Oral Anticoagulants) without explicit instruction from your treating physician. Temporary cessation of Heparin for 24 hours and oral anticoagulants for 3โ7 days prior to specimen collection may be required under strict medical supervision to prevent functional assay interference. Non-adherence may yield invalid results.
Clinical Exclusion Criteria & Emergency Red Flags
- Exclusion: Not suitable for patients experiencing acute thrombosis, pulmonary embolism, or active hemorrhage. Clinical stabilization is mandatory prior to elective thrombophilia testing.
- Emergency Red Flags: Sudden severe headache, slurred speech, chest pain, difficulty breathing, unilateral leg swelling with pain, or signs of stroke. If you experience any of these symptoms, seek immediate emergency care by calling 998.
- Important Considerations: Recent anticoagulant therapy may severely impact test accuracy and must be reviewed. For minors, parental or legal guardian consent is required in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the Factor V Functional Test used for?
This test measures the biological activity of Factor V, a critical protein in the coagulation cascade. It is primarily used to diagnose Factor V deficiency (a rare bleeding disorder) and Activated Protein C Resistance (APC-R), which is the most common inherited cause of thrombophilia (excessive blood clotting), most frequently due to the Factor V Leiden mutation.
2. How should I prepare for the Factor V Functional Test?
Preparation involves an overnight fasting period. Crucially, you must consult your prescribing physician regarding the temporary cessation of anticoagulant medications. Heparin typically requires a 24-hour washout, while oral anticoagulants may require 3 to 7 days. Do not stop any medication without direct medical authorization. Ensure your phlebotomist is informed of all medications you are currently taking.
3. What do abnormal results from the Factor V Functional Test indicate?
Low Factor V activity levels suggest a quantitative deficiency, which may be congenital or acquired (e.g., liver disease, disseminated intravascular coagulation). A reduced response to Activated Protein C (APC-R) indicates a functional resistance, strongly associated with the hereditary Factor V Leiden mutation. Abnormal results should be correlated with clinical history and confirmed via molecular genetic testing before definitive diagnosis or treatment changes are implemented.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates in full compliance with the UAE legislative framework for healthcare data privacy and clinical safety. All patient data, including coagulation profiles, are processed under the strict provisions of Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL). Our health information systems adhere to the security standards mandated by Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical laboratory practices and patient consent protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. This regulatory triad ensures the highest levels of data integrity, patient confidentiality, and clinical accountability.
Clinical & Logistical Metadata
| Test Name | Factor V Functional Test |
| Price (AED) | 650 |
| Turnaround Time | Next working day (sample collected Thu by 9 AM) |
| Sample Type / Matrix | Citrated plasma (peripheral whole blood) |
| Methodology Used | Electromechanical Clot Detection (functional assay) |
| ICD-10-CM Code | D68.51 (Factor V Leiden mutation) |
| LOINC Code | 6303-6 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians