GDAP1 Gene CMT2K Genetic Test in UAE | 2800 AED | NGS Sequencing | DNA Labs UAE

Executive Summary & Core Metrics

This advanced genetic test utilizes Next-Generation Sequencing (NGS) to detect pathogenic variants in the GDAP1 gene, providing a definitive diagnosis for Charcot-Marie-Tooth disease type 2K (CMT2K). The test is conducted at DNA Labs UAE, a DHA-licensed facility, ensuring compliance with UAE Federal laws and ISO standards.

Accuracy Guarantee: Over 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Telephonic Post-Test Clinical Guidance and mandatory pre-test genetic counseling included.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The GDAP1 Gene CMT2K Genetic Test is designed for individuals exhibiting clinical symptoms of hereditary motor and sensory neuropathy. By employing NGS technology, the test provides a comprehensive analysis of the GDAP1 gene, identifying point mutations, small insertions, and deletions with high precision. This method is superior to traditional Sanger sequencing for initial diagnostic screening due to its higher throughput and sensitivity.

Feature	Our Test (NGS)	Closest Alternative (Sanger Sequencing)
Methodology	Next-Generation Sequencing (NGS)	Sanger Sequencing (single gene)
Turnaround Time	3–4 Weeks	6–8 Weeks
Analytical Sensitivity	>99.9% for SNVs, indels	Limited; may miss deep intronic variants
Sample Type	Whole Blood, Extracted DNA, Dried Blood Spot (FTA Card)	Whole Blood only

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA 9294403):

"A positive result must always be correlated with the patient's clinical phenotype and detailed family history. Comprehensive genetic counseling, both before and after testing, is not just recommended—it is an integral part of the diagnostic journey. This test provides critical data, but it is one piece of a larger clinical puzzle."

Pre-Test Advisory & Sample Requirements

Mandatory Pre-Test Genetic Counseling: A session with our genetic counselor is required before sample collection to construct a pedigree chart of affected family members. This ensures accurate test interpretation and informed patient consent in line with Federal Decree-Law No. 4 of 2016 on Medical Liability.

Medication Advisory: Do not discontinue any prescribed medication without consulting your treating physician. This genetic test does not replace clinical judgment or urgent medical care.

Exclusion Criteria & Emergency Red Flags

Exclusion: Individuals who have received a blood transfusion within the past 2 weeks; an alternative sample (buccal swab) may be considered. Minors require informed parental consent.
Emergency Red Flags: If you experience sudden, severe neurological symptoms such as acute limb weakness, difficulty breathing, or loss of consciousness, seek emergency medical attention immediately. Do not wait for test results.

Patient FAQ & Clinical Guidance

1. What is the GDAP1 Gene CMT2K NGS test, and why is it performed?

Answer: This advanced genetic test detects mutations in the GDAP1 gene responsible for Charcot-Marie-Tooth disease type 2K, an inherited neurological condition. It is performed to confirm a clinical diagnosis, guide prognosis, and facilitate informed family planning. The test is recommended for individuals with clinical signs of CMT2K, such as progressive distal muscle weakness and sensory loss, supported by nerve conduction studies.

2. How accurate is this test, and when will I receive my results?

Answer: The test achieves over 99.9% analytical sensitivity for point mutations and small indels using NGS technology. Results are typically delivered within 3 to 4 weeks. The high coverage depth ensures reliable detection of variants, and our ISO-certified processing pipeline minimizes the risk of false negatives. Pre-test counseling ensures you fully understand the potential outcomes and implications.

3. Can I take this test if I am currently on medication for other conditions?

Answer: Yes, you can take this test. However, you should not alter or discontinue any prescribed medications without consulting your doctor. This genetic test is purely diagnostic and does not assess drug levels or interactions. Always communicate openly with your healthcare provider about all medications you are taking.

UAE Regulatory & Data Privacy Adherence

DNA Labs UAE strictly complies with the UAE's comprehensive data protection and healthcare regulations. Patient data is handled with the highest level of confidentiality and security.

Data Privacy: Governed by Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
Health Information: Managed in accordance with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Medical Liability & Consent: All clinical procedures, including pre-test counseling and sample collection, adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Quality Management: Our laboratory operates under an ISO 9001:2015 certified quality management system.

Our commitment to these frameworks ensures that your medical data is protected, and your care is delivered to the highest clinical standards.

Clinical & Logistical Metadata

Test Name	GDAP1 Gene CMT2K Genetic Test (NGS)
Price (AED)	2,800 AED
Turnaround Time	3–4 Weeks
Sample Type / Matrix	Whole Blood, Extracted DNA, Dried Blood Spot (FTA Card)
Methodology Used	Next-Generation Sequencing (NGS)
ICD-10-CM Code	G60.0
LOINC Code	94873-2
DHA Facility License & Laboratory Address	License #1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE