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Test Price

1,000 AED

✅ Home Collection Available

VNTR Chimerism Analysis (Post-BMT) – 1000 AED – UAE

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM – 11 PM).
  • Clinical Guidance: Post-test telephonic interpretation support by senior laboratory specialists.
  • Insurance: Direct Billing Verification – send your policy via WhatsApp +971 54 548 8731

Test Overview & Methodology

This test quantifies donor‑recipient chimerism after bone marrow transplant using Variable Number Tandem Repeat (VNTR) analysis by End‑Point PCR. It detects the proportion of donor vs. recipient DNA in peripheral blood, enabling precise monitoring of engraftment, early detection of graft failure, and molecular relapse assessment.

Feature Our Test (VNTR Chimerism – End‑Point PCR) Closest Alternative (STR Analysis by Capillary Electrophoresis)
Precision 99.9% diagnostic sensitivity; validated VNTR loci with high heterozygosity Standard STR multiplex; lower informativeness in certain populations
Methodology Endpoint PCR with proprietary ISO‑calibrated detection PCR + capillary electrophoresis; fewer robust loci for post-BMT monitoring
Turnaround Time 3–4 working days (express option available) 5–7 working days on average

Physician Insight & Safety Protocols

“As a medical geneticist, I emphasise that VNTR chimerism results must always be integrated with the patient’s full clinical picture – including immunosuppression history, blood counts, and donor‑specific antibodies. A rising recipient DNA fraction can herald graft failure or relapse; serial monitoring is therefore essential. Never modify immunosuppressive therapy without comprehensive clinical evaluation.

— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA: 9294403)

Advisory: Pre‑Collection Precautions

This test requires a valid doctor’s prescription. Do not discontinue any prescribed immunosuppressive, corticosteroid, or antimicrobial therapy prior to sample collection unless explicitly directed by your transplant physician. If you experience fever, severe bruising, uncontrolled bleeding, or signs of acute graft‑versus‑host disease (skin rash, diarrhea, jaundice), seek immediate medical attention – do not wait for test results.

Exclusion: Patient Eligibility & Consent

Patients under 18 years require guardian consent in accordance with Federal Decree‑Law No. 4 of 2016 on Medical Liability. This test is not intended for use as a sole basis for clinical decisions; it must be interpreted by a qualified physician. Home collection is not available for patients requiring strict clinical supervision – hospital extraction only for such cases.

Patient FAQ & Clinical Guidance

1. How does the VNTR Chimerism test detect graft failure earlier than blood counts?

Our endpoint PCR directly quantifies donor DNA fraction weeks before hematologic changes appear, providing a molecular early warning for intervention.

2. Can I have the sample collected at home, and is it stable during transport?

Yes, our VIP mobile phlebotomy team collects whole blood in special EDTA tubes and transports it in a 2–8°C cold chain, ensuring DNA integrity for up to 48 hours.

3. How do you protect my genetic data under UAE privacy laws?

All DNA data is encrypted, stored on UAE‑based servers, and handled strictly per Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, with no third‑party sharing.

UAE Regulatory & Data Privacy Adherence

DNA Labs UAE operates under DHA Facility License No. 1143 and adheres to all UAE federal data protection and health regulations. Patient data is processed in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019. Clinical safety and patient consent follow the provisions of Federal Decree‑Law No. 4 of 2016 on Medical Liability. No data is shared with third parties without explicit consent.

Clinical & Logistical Metadata

Test Name VNTR Chimerism Analysis (Post-BMT)
Price (AED) 1000
Turnaround Time 3–4 working days (express available)
Sample Type / Matrix Whole Blood (Peripheral) – VIP Mobile Phlebotomy home collection available daily 8 AM–11 PM
Methodology Used End‑Point PCR – VNTR Analysis
ICD-10-CM Code Z94.81
LOINC Code 86214-7
DHA Facility License & Address License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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