Test Price
2,800 AED✅ Home Collection Available
GDAP1 Gene CMT4A Genetic Test – Next Generation Sequencing (NGS) | 2800 AED
Executive Summary & Core Metrics
Executive Summary
The GDAP1 Gene CMT4A NGS test uses next-generation sequencing to detect pathogenic variants in the GDAP1 gene associated with Charcot-Marie-Tooth disease type 4A. The test provides 99.9% diagnostic sensitivity and includes telephonic post-test clinical guidance.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM–11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for Result Interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The GDAP1 Gene CMT4A NGS test screens for pathogenic variants in the GDAP1 gene causing Charcot-Marie-Tooth disease type 4A, a severe, early-onset hereditary motor and sensory neuropathy. This comprehensive genetic test supports accurate diagnosis for patients with hereditary neuropathy symptoms.
| Test Attributes | Our Test (GDAP1 NGS) | Closest Alternative (Single‑Gene Sanger) |
|---|---|---|
| Precision | Full gene coverage, deep intronic & regulatory variants detected by NGS | Coding exons only; limited variant detection |
| Methodology | Next Generation Sequencing (NGS) with copy number analysis | Sanger sequencing (exon‑by‑exon, no CNV detection) |
| Turnaround Time | 3‑4 Weeks | 6‑8 Weeks |
| Sample Flexibility | Whole Blood, Extracted DNA, or Dried Blood Spot (FTA® Card) | Whole Blood only |
Physician Insight & Safety Protocols
“While this genetic test identifies GDAP1 mutations linked to CMT4A, clinical correlation with neurological examination and family history is essential. A negative result does not exclude other genetic forms of Charcot-Marie-Tooth disease. Always discuss results with your neurologist.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA ID: 9294403
Advisory Notice
Do not discontinue prescribed medication without consulting your doctor. Genetic results do not replace ongoing clinical management.
Exclusion Criteria & Red Flags
- Not indicated for individuals without clinical suspicion of hereditary neuropathy or positive family history.
- Requires a pre‑test genetic counselling session to document pedigree (mandatory).
- 🆘 Seek immediate medical attention if you experience sudden muscle weakness, respiratory difficulty, severe neuropathic pain, or loss of ambulation.
Patient FAQ & Clinical Guidance
1. What is the GDAP1 gene and its role in CMT4A?
This NGS test sequences the entire GDAP1 gene to identify variants responsible for Charcot-Marie-Tooth disease type 4A, a severe autosomal recessive neuropathy.
2. How is the test performed and what sample is required?
A simple blood draw, one drop of blood on an FTA card, or previously extracted DNA is accepted. Home collection is available 8 AM–11 PM via our VIP mobile phlebotomy service.
3. Will insurance cover this genetic test?
Direct billing verification is offered via WhatsApp at +971 54 548 8731. Many UAE insurers cover medically necessary hereditary neuropathy panels.
UAE Regulatory & Data Privacy Adherence
All genetic testing services at DNA Labs UAE comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | GDAP1 Gene CMT4A Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or Dried Blood Spot (FTA® Card) |
| Methodology Used | Next Generation Sequencing (NGS) with Copy Number Variation (CNV) analysis |
| ICD-10-CM Code | G60.0 |
| LOINC Code | 81252-4 |
| DHA Facility License & Laboratory Address | 1143 · Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE · DNA Labs UAE |
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