Test Price
130 AED✅ Home Collection Available
Tissue Transglutaminase (tTG) Antibody IgA Test in UAE | 130 AED | DHA Licensed
Executive Summary & Core Metrics
Clinical Excellence & Patient Convenience
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
- Turnaround: Same day for samples received by 9 AM.
Key Metrics at a Glance
- Price: 130 AED (all-inclusive)
- Sample Type: Serum (SST)
- Methodology: Quantitative ELISA (EIA)
- ICD-10-CM: K90.0 (Celiac Disease)
- LOINC: 18358-4
Test Overview & Methodology
The Tissue Transglutaminase (tTG) Antibody IgA test is the primary serological screening tool for celiac disease, an autoimmune enteropathy triggered by gluten. Quantitative Enzyme Immunoassay (ELISA) measurement enables reliable, same-day detection of IgA autoantibodies with high clinical specificity and sensitivity.
| Feature | Our tTG IgA ELISA Test | Closest Alternative (Endomysial IgA / Total IgA + tTG IgG) |
|---|---|---|
| Methodology | Quantitative ELISA (EIA) – Automated, High-Sensitivity | Indirect Immunofluorescence (EMA) or separate IgG ELISA |
| Diagnostic Sensitivity | >95% for active celiac disease | EMA ~90% (operator-dependent); IgG only for IgA-deficient patients |
| Turnaround Time | Same Day (sample by 9 am) | 2–4 days (EMA requires specialist interpretation) |
| Sample & Logistics | 2 mL serum, SST; refrigerated/frozen transport included | Often requires paired total IgA; longer transport stability |
| Price | 130 AED | Varies (typically 200–400 AED combined) |
Physician Insight & Safety Protocols
“Clinical correlation with duodenal biopsy remains essential; an isolated positive tTG IgA does not confirm celiac disease, but titers exceeding 10× the upper limit of normal are highly specific. I strongly recommend discussing all serological findings with your gastroenterologist before making dietary changes.”
— Dr. Ajay Singh, General Practitioner, DHA ID: 36234132
Important Medication & Dietary Notice
Do not discontinue prescribed medication or initiate a gluten‑free diet without consulting your doctor. An accurate diagnosis requires a gluten-containing diet for at least 6 weeks prior to testing to avoid false‑negative results.
Patient Safety Exclusion Criteria & Emergency Red Flags
- IgA Deficiency: Up to 3% of celiac patients lack total IgA; a falsely negative tTG IgA may occur. Concurrent total IgA measurement is mandatory.
- Immunosuppressive Therapy: May blunt autoantibody response, leading to underestimated titers.
- ER Red Flags: Seek immediate medical care if you experience severe abdominal pain, protracted vomiting, profound weight loss, dehydration, or worsening dermatitis herpetiformis blisters.
- Pediatric Consideration: Children under 2 years require careful interpretation alongside age‑specific reference ranges.
Patient FAQ & Clinical Guidance
1. What is the tTG IgA test, and why is it the preferred first-line screening for celiac disease?
The tTG IgA test identifies gluten-induced autoantibodies with over 95% sensitivity for active celiac disease. It targets the enzyme tissue transglutaminase, the autoantigen central to celiac pathogenesis, and provides a quantitative, reproducible result that correlates with mucosal damage severity. A positive result prompts endoscopic biopsy for definitive diagnosis.
2. How accurate is this test, and can it replace intestinal biopsy?
tTG IgA ELISA reaches 97% specificity and 96% positive predictive value in symptomatic patients with adequate gluten intake. Although high‑titer results (>10× ULN) suggest villous atrophy, current guidelines require duodenal biopsy for confirmation. The test cannot fully replace histology but reduces unnecessary endoscopies when negative.
3. Do I need to eat gluten before the blood draw for accurate results?
Yes, a daily gluten intake equivalent to 2 slices of wheat bread for 6–8 weeks is mandatory. Eliminating gluten before testing suppresses autoantibody production and risks a false‑negative result. If already on a gluten‑free diet, a medically supervised gluten challenge may be advised.
UAE Regulatory & Data Privacy Adherence
Trust & Compliance Framework
At DNA Labs UAE, we strictly adhere to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your health data is handled with the highest security and confidentiality. All clinical procedures comply with Federal Decree-Law No. 4 of 2016 on Medical Liability regarding patient safety and informed consent.
Our laboratory is fully licensed by the Dubai Health Authority (DHA) and follows international standards for diagnostic accuracy and patient privacy.
Clinical & Logistical Metadata
| Test Name | Tissue Transglutaminase (tTG) Antibody IgA |
| Price (AED) | 130 |
| Turnaround Time | Same Day (sample by 9 AM) |
| Sample Type / Matrix | Serum (SST) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available |
| Methodology Used | Quantitative Enzyme-Linked Immunosorbent Assay (ELISA) |
| ICD-10-CM Code | K90.0 |
| LOINC Code | 18358-4 |
| DHA Facility License & Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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