Lp-PLA2 (Lipoprotein-Associated Phospholipase A2) Activity Test – Cardiovascular Risk Assessment

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Telephonic post-test result interpretation by DHA-certified clinical team.
Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

The Lp-PLA2 activity test quantifies vascular-specific inflammation directly linked to atherosclerotic plaque instability – a critical predictor of heart attack and stroke risk. This advanced assay uses CLIA (chemiluminescent immunoassay) methodology, offering clinicians a reliable tool to stratify patients with intermediate cardiovascular risk beyond traditional lipid markers.

Feature	Our Lp-PLA2 Activity Test (CLIA)	Closest Alternative (Lp-PLA2 Mass ELISA)
Precision & Specificity	>99% diagnostic sensitivity for plaque-derived inflammation	Moderate; may detect inactive enzyme mass
Turnaround Time	10 working days (ISO-accredited lab)	7–14 days, variable quality
Clinical Relevance	Direct enzymatic activity reflecting plaque vulnerability	Total protein concentration; may not correlate with activity
Clinical Utility	Enhanced risk stratification for primary prevention patients	Limited to inflammatory marker screening

Physician Insight & Safety Protocols

“As a general practitioner, I consider the Lp-PLA2 activity test an essential component of cardiovascular risk evaluation. When combined with traditional lipid profiles and lifestyle factors, it provides actionable insight into arterial inflammation. Always review results with your doctor – never self-adjust medications without professional guidance.”

— Dr. Ajay Singh, General Practitioner, DHA Registration ID: 36234132

Medication Advisory

⚠️ Important Medication Advisory

Do not discontinue any prescribed medication, especially antithrombotics, statins, or antihypertensives, without consulting your supervising physician. The Lp-PLA2 test is a risk assessment tool, not a substitute for ongoing medical management.

Exclusion Criteria & Emergency Alerts

Exclusion Criteria & Red Flags

Exclusion Criteria: Active infection or acute inflammatory state, major surgery within 4 weeks, current high-dose corticosteroid or immunosuppressive therapy.
ER Red Flags: If you experience sudden chest pain, severe shortness of breath, palpitations with dizziness, or fainting, seek emergency medical care immediately. This test does not diagnose acute coronary events.

Patient FAQ & Clinical Guidance

1. What does the Lp-PLA2 activity test measure?

The Lp-PLA2 activity test measures vascular-specific inflammation associated with atherosclerotic plaque vulnerability and cardiovascular event risk. It evaluates the enzymatic activity of lipoprotein-associated phospholipase A2, an enzyme produced by inflammatory cells within arterial plaques. Elevated activity indicates an unstable plaque environment, guiding physicians in intensifying preventive strategies beyond standard cholesterol management.

2. How should I prepare for this test?

Overnight fasting for 8–12 hours is preferred to ensure accurate measurement of Lp-PLA2 activity levels. Only water is allowed during the fasting window. Inform our phlebotomist about any medications or supplements you are taking, as certain anti-inflammatory drugs or high-dose steroids may interfere. Home collection is arranged within 8 AM – 11 PM, with cold-chain transport guaranteeing sample integrity.

3. When will I receive my Lp-PLA2 test results?

Lp-PLA2 results are available within 10 working days after sample collection at our lab. The report is generated through ISO 9001:2015 certified processes and reviewed by DHA-licensed clinical staff. You will receive a secure digital copy and, on request, a telephonic clinical interpretation. Urgent critical values are communicated immediately.

4. Can this test replace a standard lipid profile?

No, the Lp-PLA2 activity test is a complementary marker, not a replacement. It provides additional information about vascular inflammation that is not captured by LDL cholesterol or other routine lipids. Your doctor will interpret both results together to build a comprehensive cardiovascular risk profile.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance & Data Protection

This diagnostic service operates in full compliance with:

Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring confidentiality of patient health records.
Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Federal Decree-Law No. 4 of 2016 on Medical Liability – governing patient consent and clinical safety standards.
DHA Facility License Number: 1143

Our lab is ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) and follows strict quality assurance protocols.

Clinical & Logistical Metadata

Test Name	Lp-PLA2 (Lipoprotein-Associated Phospholipase A2) Activity Test
Price (AED)	450 AED
Turnaround Time	10 working days
Sample Type / Matrix	Blood – Serum or Plasma (standard peripheral whole blood)
Methodology Used	CLIA (Chemiluminescent Immunoassay)
ICD-10-CM Code	Z13.6 (Encounter for screening for cardiovascular disorders)
LOINC Code	44142-7 (Lipoprotein-associated phospholipase A2 activity in Serum or Plasma)
DHA Facility License & Laboratory Address	DHA License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. Corporate Lab: DNA Labs UAE