Ber-Ep4 (EpCAM) Immunohistochemistry Test in UAE | 550 AED

Executive Summary & Core Metrics

Diagnostic Accuracy: 99.9% sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).

Specimen Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – formalin-fixed paraffin-embedded blocks transported under controlled ambient conditions.

Physician Guidance: Telephonic post-test clinical interpretation by a DHA-licensed Specialist Diagnostic Radiologist.

Insurance & Billing: Direct billing verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The Ber-Ep4 (EpCAM) immunohistochemistry test detects the epithelial cell adhesion molecule (EpCAM) in formalin-fixed paraffin-embedded (FFPE) tumor tissue. This monoclonal antibody assay enables precise classification of carcinomas of unknown primary and confirms epithelial lineage in diagnostically challenging cases. The procedure is performed on archival tissue specimens using automated staining platforms validated under ISO 9001:2015 quality management standards. A complete histopathology report, biopsy site documentation, and clinical history must accompany each specimen for accurate interpretation.

Feature	Ber-Ep4 IHC (Our Service)	Standard EpCAM IHC (Alternative)
Methodology	ISO-validated monoclonal antibody with automated staining platforms	Manual or semi-automated conventional IHC
Turnaround Time	5 days (standard biopsy), 7 days (large or complex specimens)	7–10 working days
Sample Requirement	FFPE block or 10% formalin-saline fixed tissue; room-temperature courier	Similar, but often lacks dedicated retrieval logistics
Accreditation	ISO 9001:2015 (INT/EGQ/2509DA/3139), DHA facility license 1143	Varies; may lack ISO certification
Price	550 AED	600–700 AED

All tests require a copy of the histopathology report, biopsy site, and complete clinical history. Pre-test submission checklist: histopathology report, biopsy site documentation, and clinical summary.

Physician Insight & Safety Protocols

Mr. Prabhakar Reddy Kalathoor | Specialist Diagnostic Radiology | DHA Registration ID: 61713011

“Ber-Ep4 IHC provides valuable diagnostic information for classifying carcinomas of unknown primary. The result must always be interpreted alongside morphological findings, complementary IHC markers, and the full clinical picture. Clinical decisions should not rely exclusively on this single marker.”

Advisory: Medication and Treatment Continuity

Do not discontinue prescribed medications or alter cancer therapy without consulting your treating physician. The Ber-Ep4 test is a diagnostic adjunct and should not be used as the sole basis for treatment modifications.

Exclusion Criteria & Safety Red Flags

The test is contraindicated when tissue fixation uses other than 10% neutral-buffered formalin or when the FFPE block is compromised. Patients with known hypersensitivity to any IHC reagent component should inform the laboratory prior to processing. Seek emergency medical attention for severe bleeding at the biopsy site, sudden swelling, high fever, or dyspnea. Specimen procurement is performed exclusively within a hospital environment under standard surgical biopsy protocols; no direct patient venipuncture is required.

Patient FAQ & Clinical Guidance

1. What is the Ber-Ep4 (EpCAM) Immunohistochemistry test?

Answer: The Ber-Ep4 (EpCAM) IHC test detects EpCAM protein in tumor tissue to confirm epithelial origin and guide cancer classification. It is a specialized laboratory stain applied to a small piece of tumor from a biopsy or surgical resection. The presence of EpCAM helps pathologists determine whether a cancer originated in epithelial sites such as the colon, breast, or lung. This test is performed on archival FFPE tissue and does not require a new specimen collection from the patient.

2. How should I prepare for the Ber-Ep4 test and are there special instructions?

Answer: No special patient preparation is required because the test is performed on previously collected tissue, not on a fresh blood or fluid sample. The laboratory requires only the formalin-fixed tissue block or prepared slides, accompanied by the histopathology report and clinical history. Ensure your referring physician provides the biopsy site and relevant medical background. A medical courier will retrieve the archival specimen from the hospital or pathology archive under a controlled chain of custody.

3. What do the results mean and when will I receive the report?

Answer: A positive Ber-Ep4 result indicates strong EpCAM expression, strongly suggesting the carcinoma originated from epithelial tissue. A negative result may point toward non-epithelial tumors or poor tissue preservation. Your oncologist will integrate this finding with all other diagnostic data to reach a final diagnosis. Reports for standard biopsy specimens are available within 5 days; large or complex specimens may require up to 7 days. Post-test telephone consultation with a DHA-licensed specialist is included for result interpretation.

UAE Regulatory & Data Privacy Adherence

Data Protection: All patient data is processed in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.

Clinical Safety & Consent: Specimen collection and diagnostic procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring informed consent and patient safety throughout the diagnostic pathway.

Accreditation: DNA Labs UAE operates under DHA Facility License No. 1143 and ISO 9001:2015 certification (INT/EGQ/2509DA/3139).

Clinical & Logistical Metadata

Test Name	Ber-Ep4 (EpCAM) Immunohistochemistry
Price (AED)	550 AED
Turnaround Time	5 to 7 working days
Sample Type / Matrix	FFPE Tissue Block / 10% Formalin-Saline Fixed Tissue
Methodology Used	Immunohistochemistry (IHC) with ISO-Validated Monoclonal Antibody – Automated Staining Platform
ICD-10-CM Code	C80.1 (Malignant neoplasm of unspecified site)
LOINC Code	93469-7 (EpCAM [Epithelial cell adhesion molecule] [Presence] in Tissue by Immune stain)
DHA Facility License & Laboratory Address	License No. 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE