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Test Price

2,800 AED

✅ Home Collection Available

CALR Gene (Schizophrenia Susceptibility) Genetic Test – 2,800 AED

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
  • Clinical Guidance: Telephonic Post-Test Interpretation by a DHA-Licensed Genetic Counselor.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This NGS test analyzes the CALR gene for mutations associated with schizophrenia susceptibility, delivering comprehensive variant detection using next-generation sequencing with copy number variation (CNV) calling. The method employs Illumina NGS technology, achieving >99.9% sensitivity across the full coding region.

Feature Our Test Closest Alternative
Precision NGS – full coding region, >99.9% sensitivity Single‑gene PCR/sequencing – limited to known hotspots
Method Illumina NGS with CNV calling (ISO 9001:2015) Sanger sequencing / array‑based genotyping
Turnaround 3 to 4 Weeks 4 to 8 Weeks

Physician Insight & Safety Protocols

“Genetic testing for schizophrenia susceptibility, including the CALR gene, provides valuable insights into individual risk profiles but must be interpreted alongside full clinical evaluation and family history. A positive result indicates increased predisposition, not a diagnosis. Results should be discussed with a treating psychiatrist or neurologist.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory: Medication Management

⚠ Medication Warning: Do not discontinue prescribed antipsychotic or mood‑stabilizing medication without consulting your doctor.

Exclusion Criteria and Emergency Red Flags

Exclusion Criteria

  • Recent blood transfusion (<2 weeks).
  • Inability to provide informed consent or participate in genetic counselling.
  • Acute febrile illness at time of collection.

Emergency Red Flags – Seek Immediate ER Care if:

  • Sudden hallucinations, paranoia, or delusions.
  • Suicidal ideation or self‑harm thoughts.
  • Severe extrapyramidal symptoms (rigidity, dystonia).

Patient FAQ & Clinical Guidance

1. What does a positive CALR gene mutation indicate for schizophrenia risk?

A positive CALR variant indicates an increased susceptibility to schizophrenia, but does not guarantee disease onset. Further clinical assessment, including psychiatric evaluation and family history, is mandatory.

2. How should I prepare for this genetic test?

No fasting or special preparation is needed. A blood sample, buccal swab, or dried blood spot can be collected at home by our nurse during the scheduled home collection visit.

3. Is genetic counseling included?

Yes, a mandatory pre‑test genetic counseling session is included to obtain family history, construct a pedigree, and provide informed consent, ensuring accurate risk assessment.

4. What are the pre‑test requirements?

You need to submit a clinical history and complete a genetic counseling session to construct a family pedigree for CALR‑associated schizophrenia risk assessment.

UAE Regulatory & Data Privacy Adherence

This service complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree‑Law No. 4 of 2016 on Medical Liability. The laboratory is ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).

Clinical & Logistical Metadata

Test Name CALR Gene (Schizophrenia Susceptibility) Genetic Test
Price (AED) 2,800
Turnaround Time 3 to 4 Weeks
Sample Type / Matrix Peripheral blood, buccal swab, or dried blood spot
Methodology Used Next‑Generation Sequencing (NGS) with CNV calling (ISO 9001:2015)
ICD‑10‑CM Code Z13.89
LOINC Code 94120-2
DHA Facility License & Laboratory Address License 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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