Test Price
1,200 AED✅ Home Collection Available
BCR-ABL Variant Panel (Mbcr-b2a2, b3a2, b2a3) in UAE | 1200 AED | 2026 DHA Guidelines
Gold-standard multiplex endpoint PCR | Bone Marrow / Peripheral Blood | TAT 5–7 Days | ISO 9001:2015 Certified
تحليل لوحة متغيرات BCR-ABL في الإمارات | 1200 درهم | معتمد من هيئة الصحة بدبي
Executive Summary & Compliance
الملخص التنفيذي: تحليل جيني دقيق بنسبة 99.9%، خدمة جمع منزلي فاخرة، وإرشاد طبي ما بعد الفحص.
Accuracy Guarantee: 99.9% diagnostic sensitivity via multiplex endpoint PCR in an ISO 9001:2015 certified Dubai facility.
Premium Logistics: Paid hospital-grade home collection with ISO-certified cold‑chain transport. VIP Mobile Phlebotomy available from 8 AM to 11 PM.
Clinical Guidance: Complimentary telephonic post‑test result interpretation by a healthcare professional.
Insurance Support: Direct billing verification – send your Emirates ID and policy via WhatsApp to +971 54 548 8731.
Overview: Why This Test Matters
The BCR-ABL Variant Panel detects the specific fusion transcript variants b2a2, b3a2, and b2a3 (p210 major breakpoint cluster region), crucial for diagnosing and monitoring chronic myeloid leukemia (CML) and Philadelphia chromosome‑positive acute lymphoblastic leukemia (Ph+ ALL). This molecular assay guides tyrosine kinase inhibitor selection and measures treatment response at a genetic level.
يكشف هذا التحليل عن طفرات الاندماج الجيني BCR-ABL (b2a2، b3a2، b2a3) لتشخيص ومتابعة ابيضاض الدم النقوي المزمن وابيضاض الأرومات اللمفاوية الحاد موجب كروموسوم فيلادلفيا.
| Feature | Our BCR-ABL Variant Panel | Standard BCR-ABL qPCR |
|---|---|---|
| Detection Method | Multiplex End Point PCR – identifies individual variants (b2a2, b3a2, b2a3) | Quantitative real‑time PCR – total BCR-ABL (often p210 only) |
| Clinical Specificity | High – distinct transcript sub‑types for tailored therapy | Moderate – does not resolve individual splice variants |
| Turnaround Time | 5–7 working days | 7–10 working days |
| Price | 1200 AED | ~950–1100 AED (variable) |
Our panel surpasses standard qPCR by pinpointing the exact variant, enabling European LeukemiaNet (ELN)‑guided patient management.
Physician Insight & Safety Protocol
Dr. Prabhakar Reddy (DHA License: 61713011, Consultant Oncologist): “Molecular findings from this panel must be correlated with complete blood counts, bone marrow aspirate, and clinical symptoms. Never interpret a result in isolation – a haematologist’s evaluation is essential for therapeutic decisions.”
⚠️ Important Medication Warning:
Do not discontinue or adjust prescribed tyrosine kinase inhibitors (imatinib, dasatinib, nilotinib, etc.) without consulting your treating oncologist. Altering therapy based solely on a single PCR result can lead to disease progression.
🚨 Patient Safety Exclusion & Emergency Red Flags
- Exclusion Criteria: Patients with active severe infection (sepsis, febrile neutropenia) or hemodynamic instability should postpone elective bone marrow collection until clinically stable.
- Immediate Medical Attention Required If: You develop sudden high fever (>38.5 °C), uncontrolled bleeding/bruising, severe bone pain, or visual disturbances – these may indicate leukostasis or blast crisis.
- Bone Marrow Procedure: Only performed by a licensed healthcare professional; local anaesthesia is used, but inform the team of any bleeding disorders or anticoagulant use.
Patient FAQ & Clinical Guidance
Q: What specific variants does the BCR-ABL panel detect? ما المتغيرات التي يكشفها تحليل لوحة BCR-ABL؟
This panel accurately identifies major breakpoint cluster region transcripts b2a2, b3a2, and b2a3 (p210), which are essential molecular markers for chronic myeloid leukemia and Ph+ ALL.
يحدد هذا التحليل بدقة نسخ الاندماج b2a2 و b3a2 و b2a3 (p210) وهي العلامات الجزيئية الأساسية لابيضاض الدم النقوي المزمن وسرطان الدم اللمفاوي الحاد.
Q: Is a doctor’s prescription mandatory for this in the UAE? هل يتطلب هذا الفحص وصفة طبية إلزامية في الإمارات؟
Yes, a valid prescription from a DHA‑licensed physician is compulsory, except for pre‑surgical clearance, pregnancy‑related screening, or international travel documentation as per DHA circulars.
نعم، يلزم وصفة طبية سارية من طبيب مرخص من هيئة الصحة بدبي، باستثناء فحوصات ما قبل الجراحة أو الحمل أو السفر للخارج.
Q: How should I prepare for the BCR-ABL sample collection? كيف أستعد لجمع عينة BCR-ABL؟
No fasting is required; simply inform the phlebotomist of any anticoagulant medications, and bone marrow draws are performed under strict aseptic conditions by a specialist.
لا يشترط الصيام؛ أخبر أخصائي سحب الدم عن أي مميعات دم، ويتم سحب نخاع العظم بتعقيم كامل.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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