Test Price
800 AED✅ Home Collection Available
FISH for BCR-ABL1 Translocation (Philadelphia Chromosome) Test in UAE | 800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
- Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. This test may require bone marrow aspirate, an invasive procedure, or peripheral blood drawn in a clinical setting.
- Clinical Guidance: Telephonic post-test clinical guidance by a DHA-certified Consultant Medical Genetics for result interpretation and next steps.
- Insurance: Direct billing verification and pre-approval assistance via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The FISH for BCR-ABL1 (Philadelphia chromosome) test detects the t(9;22)(q34;q11.2) translocation in blood or bone marrow using fluorescence in‑situ hybridization, serving as the cornerstone for diagnosing and monitoring chronic myeloid leukemia (CML) and Philadelphia chromosome‑positive acute lymphoblastic leukemia (Ph+ ALL).
| Parameter | Our Test (Locus‑Specific FISH) | Closest Alternative (Conventional Karyotyping) |
|---|---|---|
| Analytical Precision | 99.9% sensitivity for BCR-ABL1 fusion | ~90% sensitivity; limited by metaphase quality |
| Methodology | FISH with dual‑fusion probes (BCR/ABL1 loci) | G‑banded chromosome analysis (2‑3 week culture) |
| Turnaround Time | 4 working days | 14–21 working days |
| Sample Volume | 5 mL blood or 4 mL bone marrow | 3–5 mL bone marrow or 5 mL blood (high cellularity) |
| Clinical Utility | Diagnosis, minimal residual disease monitoring, TKI eligibility | Wide chromosomal survey, but time‑consuming for emergent Ph status |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I understand the critical importance of rapid and accurate detection of the Philadelphia chromosome for initiating targeted therapy. The BCR-ABL FISH test provides definitive diagnosis and monitoring guidance. Patients should always discuss results with their oncology team for comprehensive management.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue any prescribed medication, especially tyrosine kinase inhibitors or chemotherapy, without direct consultation with your managing physician. Abrupt cessation may lead to disease relapse or blast crisis.
Safety Exclusion Criteria & Emergency Red Flags
Exclusion Criteria (Do Not Proceed with Collection)
- Active systemic infection or skin breakdown at the procedure site.
- Severe thrombocytopenia (platelets <20×10⁹/L) without prophylactic platelet transfusion.
- Inability to provide valid informed consent (mandatory per UAE PDPL and Federal Decree-Law No. 4 of 2016 on Medical Liability).
Immediate Emergency Room Visit Recommended
- New‑onset fever >38.5 °C with neutropenia.
- Uncontrolled bleeding or bruising.
- Severe bone pain, sudden visual changes, or neurological deficits.
- Oliguria, confusion, or cardiac palpitations (suggestive of tumor lysis syndrome).
Patient FAQ & Clinical Guidance
1. What is the FISH BCR‑ABL test used for?
The FISH BCR‑ABL translocation test uses fluorescent probes to visualize the BCR‑ABL1 gene fusion in blood or bone marrow cells, providing a definitive diagnosis for Philadelphia chromosome‑positive leukemias like CML and Ph+ ALL. It also monitors minimal residual disease after treatment and guides targeted therapy with tyrosine kinase inhibitors.
2. What sample is required and how is it collected?
The test requires either 5 mL of whole blood (minimum 3 mL) or 4 mL of bone marrow aspirate (minimum 2 mL) collected in two sodium‑heparin green‑top tubes. Collection is performed in a hospital setting only, under sterile conditions by qualified phlebotomists or clinicians. A duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
3. How quickly will I receive the results?
Results are reported within 4 working days after sample receipt by 4 pm daily. All reports include a telephonic clinical correlation session with a DHA‑licensed Consultant Medical Genetics to help interpret the findings and plan next steps with your oncologist.
4. Does insurance cover this test?
We assist with direct billing verification and pre-approval. Contact our WhatsApp at +971 54 548 8731 to check your coverage.
UAE Regulatory & Data Privacy Adherence
- DHA Facility License Number: 1143
- Licensed by DHA/MOHAP; certified to ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
- All procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Personal health data handled per UAE PDPL (Federal Decree-Law No. 45 of 2021) and stored exclusively on UAE-based servers.
Clinical & Logistical Metadata
| Test Name | FISH for BCR-ABL1 Translocation (Philadelphia Chromosome) |
| Price (AED) | 800 AED |
| Turnaround Time | 4 working days |
| Sample Type / Matrix | Peripheral blood (5 mL) or bone marrow aspirate (4 mL) in sodium heparin |
| Methodology Used | Fluorescence In Situ Hybridization (FISH) with dual‑fusion probes for BCR and ABL1 |
| ICD-10-CM Code | C92.10 (Chronic myeloid leukemia, not specified), C91.00 (Acute lymphoblastic leukemia, Philadelphia chromosome positive) |
| LOINC Code | 33781-7 (BCR/ABL1 gene rearrangement by FISH) |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians