Test Price
2,800 AEDโ Home Collection Available
MKKS Gene Bardet-Biedl Syndrome Type 6 Genetic Testing in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM โ 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Result Interpretation by DHA-Licensed Genetic Counsellors.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
- DHA Facility License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Test Overview & Methodology
This Next-Generation Sequencing (NGS) test analyses the entire coding region of the MKKS gene to detect pathogenic variants causing Bardet-Biedl Syndrome type 6, a ciliopathy associated with retinal dystrophy, polydactyly, obesity, renal anomalies, and hypogonadism. Molecular confirmation enables precise family counselling, carrier detection, and tailored multidisciplinary surveillance for renal, endocrine, and visual complications.
| Feature | DNA Labs UAE โ DHA Standard | Closest Alternative |
|---|---|---|
| Methodology | NGS โ Full gene sequencing (exons + splice sites) | Targeted mutation panel / single-site analysis |
| Clinical Sensitivity | >99% for MKKS point mutations & small indels | Limited to known familial variants (~70% in some panels) |
| Turnaround Time | 3โ4 Weeks | Often 5โ6 Weeks |
| UAE Compliance | Full DHA/MOHAP & ISO 9001:2015 | Varies; may lack local accreditation |
| Post-Test Support | Bilingual genetic counselling & physician teleconsultation | Typically report-only |
Physician Insight & Safety Protocols
โGenetic confirmation of Bardet-Biedl Syndrome type 6 through comprehensive MKKS sequencing is a cornerstone of precise clinical management. The result informs renal surveillance, endocrine follow-up, and visual rehabilitation planning. I always emphasise that this test must be interpreted alongside a detailed pedigree and full phenotypic assessment to maximise diagnostic yield and avoid clinical misclassification.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
โ ๏ธ Pre-Test Medication & Clinical Advisory
Do not discontinue any prescribed medication without consulting your treating physician. This genetic test does not require specific medication adjustments. However, a complete clinical history and mandatory pre-test genetic counselling are required to ensure accurate variant interpretation and informed consent.
๐ Safety Exclusion Criteria & Red Flags
- Exclusion: Individuals unable to provide informed consent unless a legal guardian provides consent as per UAE Federal Law No. 2 of 2019 concerning health data and patient rights.
- Exclusion: Recent blood transfusion (less than 2 weeks) may interfere with DNA extraction from whole blood โ please discuss alternative sample options with the laboratory.
- Red Flag: Patients presenting with acute renal failure, rapidly deteriorating vision, or uncontrolled hypertension require urgent specialist referral; genetic testing remains elective and should not delay emergency care.
- Red Flag: Any suspicion of child abuse or neglect contributing to the clinical presentation must be reported in accordance with UAE mandatory safeguarding laws.
Patient FAQ & Clinical Guidance
1. What is the MKKS gene test and why is it important for Bardet-Biedl Syndrome type 6?
Answer: This NGS-based test examines the full coding sequence of the MKKS gene to identify disease-causing variants. Confirming the genetic subtype guides tailored management for renal, endocrine, and retinal complications, enables accurate carrier testing for family members, and supports reproductive planning.
2. What sample types are accepted and how is home collection arranged?
Answer: Accepted specimen types include peripheral whole blood, extracted DNA, or a dried blood spot on an FTA card. Our VIP Mobile Phlebotomy team performs temperature-controlled cold-chain home collection across the UAE daily from 8 AM to 11 PM.
3. How long does it take to receive results and how will they be communicated?
Answer: The standard turnaround time is 3 to 4 weeks from sample receipt. Results are delivered electronically via a secure patient portal and are reviewed during a telephonic consultation with a DHA-licensed genetic counsellor who explains the clinical implications.
4. Will my genetic data remain confidential under UAE law?
Answer: Yes. All genetic information is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Data is encrypted, access-restricted, and never shared without your explicit written consent.
5. Can this test be performed for a minor or an individual unable to consent?
Answer: Yes, with valid informed consent from a legal guardian or authorised representative. The process adheres to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring the childโs best interests are prioritised and all genetic findings are communicated appropriately.
UAE Regulatory & Data Privacy Adherence
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) โ governs the collection, storage, and processing of genetic and health data with strict encryption and access controls.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields โ mandates cybersecurity standards and patient consent for electronic health records.
- Federal Decree-Law No. 4 of 2016 on Medical Liability โ establishes the legal framework for clinical consent, patient safety, and professional accountability in genetic testing.
- ISO 9001:2015 Certified โ Quality management system certified under INT/EGQ/2509DA/3139.
- DHA Facility License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | MKKS Gene Bardet-Biedl Syndrome Type 6 Genetic Sequencing (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA), Extracted DNA, or FTA Card Dried Blood Spot |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full coding region & splice site analysis |
| ICD-10-CM Code | Q87.8 (Bardet-Biedl syndrome), Z14.8 (Genetic carrier), Z13.71 (Encounter for genetic testing) |
| LOINC Code | 81247-7 |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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