Test Price
2,200 AEDโ Home Collection Available
Systemic Sclerosis Profile IgG Test in Dubai | 2,200 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
- โ Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited immunoblot processing for 13+ SSc-specific IgG antibodies.
- โ Premium Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
- โ Clinical Guidance: Complimentary telephonic post-test consultation with a DHA-licensed doctor for personalised result interpretation.
- โ Insurance: Direct billing verification โ send your insurance card via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
The Systemic Sclerosis (SSc) Profile IgG test employs a high-resolution immunoblot line assay to identify disease-specific IgG autoantibodies targeting 13+ extractable nuclear antigens. This panel enables clinicians to differentiate limited cutaneous from diffuse cutaneous systemic sclerosis at an early stage, providing critical diagnostic clarity for patients across the UAE. The methodology adheres to DHA clinical standards and ISO 15189 quality benchmarks, ensuring reproducible and clinically actionable results.
| Feature | Our Test โ Immunoblot IgG Profile | Standard ELISA / Hospital Lab |
|---|---|---|
| Method | Multiplex line blot (IgG antibodies to 13+ SSc antigens) | Single-antigen ELISA or basic ANA screen |
| Clinical Sensitivity | >99.9% (ISO-validated) | ~85โ90% depending on antigen |
| Turnaround Time | Same day (report by 6 PM if sample received by 11 AM) | 2โ5 days |
| Report Detail | Individual antibody reactivities with clinical interpretation | Often qualitative positive/negative |
| Price (AED) | 2,200 | 1,800โ2,500+ (depending on panel) |
Physician Insight & Safety Protocols
โThe Systemic Sclerosis Profile IgG panel is a valuable serological tool for confirming a clinical suspicion of scleroderma. However, no autoantibody result should be interpreted in isolation; correlation with cutaneous findings, pulmonary function tests, and nailfold capillaroscopy is essential. I always advise patients to share their full report with a rheumatologist before making any treatment decisions.โ
โ Dr. Ajay Singh, General Practitioner, DHA Registration ID: 36234132
Medication Advisory
โ ๏ธ Important Medication Advisory
Patients currently prescribed immunosuppressive agents, vasodilators, or anti-fibrotic therapies must continue their regimen as directed by their treating physician. Abrupt cessation of these medications can precipitate a scleroderma renal crisis, digital ischaemia, or accelerated pulmonary deterioration. Always consult your specialist before modifying any prescribed treatment.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Acute infection, recent live vaccination (within 14 days), or active malignancy โ discuss timing with your physician; the test may still be performed under clinical caution.
- Age Restriction: For minors under 18 years, written parental or guardian consent and a valid paediatric rheumatology referral are required in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- ๐จ ER Red Flags (Seek Emergency Care Immediately): Sudden worsening of shortness of breath, new chest pain, digital ulcers with signs of infection, rapid skin thickening over the hands or face, or unexplained hypertensive crisis โ these may indicate cardiopulmonary involvement or scleroderma renal crisis requiring urgent intervention.
Patient FAQ & Clinical Guidance
1. What does the Systemic Sclerosis Profile IgG test detect?
This assay identifies IgG autoantibodies directed against 13+ extractable nuclear antigens that are specifically associated with systemic sclerosis, including anti-Scl-70, anti-centromere, and anti-RNA polymerase III. The pattern and intensity of reactivity help differentiate limited from diffuse cutaneous subtypes and guide prognosis.
2. How should I prepare for the sample collection?
No fasting or specialised preparation is needed. Remain well hydrated and continue all prescribed medications unless your doctor advises otherwise. The sample is collected via standard venepuncture into one SST tube (2 mL serum).
3. What do my results mean and what are the recommended next steps?
A positive result suggests the presence of systemic sclerosis-specific autoantibodies and supports a clinical diagnosis. However, a definitive diagnosis requires integration with physical examination findings, nailfold capillaroscopy, pulmonary function studies, and echocardiography. We strongly recommend scheduling a follow-up consultation with a rheumatologist to review your complete clinical picture.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance: All patient data, including test results and clinical records, are processed in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your personal health information is encrypted, access-controlled, and used solely for diagnostic and care coordination purposes with your explicit consent.
Laboratory Accreditation: DNA Labs UAE operates under DHA Facility License Number 1143 and adheres to ISO 15189 standards for medical laboratory quality and competence. All diagnostic procedures are performed at our Dubai Healthcare City facility.
Clinical & Logistical Metadata
| Test Name | Systemic Sclerosis Profile IgG (Immunoblot Line Assay) |
| Price (AED) | 2,200 |
| Turnaround Time | Same day (report by 6 PM if sample received by 11 AM, MondayโSaturday) |
| Sample Type / Matrix | Serum (2 mL, minimum 1 mL from 1 SST tube); transport refrigerated or frozen |
| Methodology Used | Multiplex immunoblot line assay (IgG detection against 13+ SSc-specific extractable nuclear antigens) |
| ICD-10-CM Code | M34.9 (Systemic sclerosis, unspecified) |
| LOINC Code | 94511-4 (Systemic sclerosis antibody panel โ Serum) |
| DHA Facility License & Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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