Test Price
2,800 AED✅ Home Collection Available
DNASE1L3 Gene Systemic Lupus Erythematosus Type 16 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل الجين DNASE1L3 المرتبط بمرض الذئبة الحمامية الجهازية النوع 16 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary / ملخص تنفيذي:
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited NGS Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ملخص: فحص جيني دقيق للكشف عن طفرات جين DNASE1L3 المرتبطة بالذئبة الحمامية، باستخدام تقنية تسلسل الجيل التالي NGS بدقة 99.9%، يتضمن خدمة جمع العينات من المنزل واستشارة جينية هاتفية بعد النتيجة، مع دعم مباشر لاستفسارات التأمين عبر الواتساب.
Test Overview
This Genetic Test analyzes the entire coding region of the DNASE1L3 gene to detect pathogenic variants associated with autosomal recessive Systemic Lupus Erythematosus type 16 (SLE16). يكشف هذا التحليل عن الطفرات المسببة لمرض الذئبة الحمامية الجهازية النوع 16 المرتبط بالجين DNASE1L3. Results inform diagnosis, familial risk assessment, and personalized management under UAE DHA oversight.
| Feature | Our Test (ISO 9001:2015) | Closest Alternative |
|---|---|---|
| Precision | NGS – full gene sequencing with >99% base accuracy | Single gene targeted mutation panel – misses rare variants |
| Methodology | Illumina® NGS platform with Sanger validation of clinically significant variants | MLPA or Sanger sequencing of select exons only |
| Speed | TAT 3–4 weeks; expedited reporting available | 5–6 weeks typical |
Physician Insight & Safety Protocol
"A positive DNASE1L3 variant does not always predict disease severity; clinical correlation with rheumatologic evaluation remains paramount. I recommend genetic counselling before and after testing to interpret the implications for family members."
— Dr. PRABHAKAR REDDY (DHA: 61713011), Consultant Rheumatology & Genetics
⚠️ Medication Warning:
Do not discontinue prescribed medication without consulting your doctor. Genetic test results should be discussed with your treating physician before any change in therapy.
Exclusion Criteria & ER Red Flags
- This test is not indicated for acute diagnosis; clinical emergencies must be managed in a hospital setting.
- ER Red Flags: If you experience sudden high fever, difficulty breathing, severe chest pain, or new-onset seizures, proceed immediately to the nearest emergency department. Do not wait for genetic results.
- Patients with active severe bleeding disorders must inform the phlebotomist before sample collection.
- Minors require legal guardian consent as per CDS Law 2026.
Patient FAQ & Clinical Guidance
Q: How accurate is the DNASE1L3 NGS test for diagnosing lupus type 16?
This test identifies >99% of pathogenic DNASE1L3 variants with near-zero false‑positives due to orthogonal confirmation, making it the most reliable genetic tool for SLE16. False negatives can occur if the mutation lies in deep intronic regions not covered by the standard panel; your genetic counsellor will discuss any limitations during the pre-test session.
يحدد هذا الاختبار أكثر من 99% من الطفرات المسببة للمرض في جين DNASE1L3 مع معدل إيجابيات كاذبة يكاد يكون صفراً بفضل التأكيد المعملي الثنائي، مما يجعله الأداة الجينية الأكثر موثوقية لتشخيص الذئبة الحمامية النوع 16.
Q: Can I use an FTA card sample instead of a blood draw?
Yes, a single drop of blood on an FTA card is accepted and offers the same diagnostic accuracy when processed within 72 hours of collection. This is particularly convenient for home collection or pediatric patients; our VIP mobile phlebotomy team will guide you through the procedure.
نعم، يمكن استخدام بقعة دم واحدة على بطاقة FTA وتعطي نفس الدقة التشخيصية إذا تم تجهيزها خلال 72 ساعة من الجمع، وهي مناسبة خاصة لجمع العينات المنزلية أو لحالات الأطفال.
Q: Does health insurance cover the DNASE1L3 gene in the UAE?
Coverage varies; our direct billing team verifies your insurance policy instantly via WhatsApp at +971 54 548 8731, and we assist with pre‑approval under DHA‑approved indications. Self‑pay patients receive a detailed invoice with ISO 9001:2015 certification for potential reimbursement.
تختلف التغطية التأمينية؛ يقوم فريق الفوترة المباشرة لدينا بالتحقق من وثيقتك فوراً عبر الواتساب على الرقم +971 54 548 8731 ومساعدتك في الحصول على موافقة مسبقة حسب مؤشرات هيئة الصحة بدبي.
Compliance & Accreditation:
- Federal Decree-Law No. 41 of 2024 (Art. 87) – Protection of genetic data.
- CDS Law 2026 – Minors’ consent and data handling.
- UAE PDPL – Personal Data Protection Law compliance.
- ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
- Facility License: 9834453.
For genetic counselling appointment: WhatsApp +971 54 548 8731 | Home collection available 8 AM – 11 PM, all Emirates.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians