Test Price
180 AED✅ Home Collection Available
Centromere Antibody Test in UAE | 180 AED
Executive Summary & Core Metrics
The Centromere Antibody test detects autoantibodies against centromere proteins with greater than 99% diagnostic specificity for limited systemic sclerosis (CREST syndrome). Utilising Enzyme-Linked Immunosorbent Assay (ELISA) under ISO 9001:2015 compliance, the test delivers quantitative results. Our VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection service is available daily from 8 AM to 11 PM. Direct billing insurance verification via WhatsApp at +971 54 548 8731. Price: 180 AED. Same-day reporting when sample is collected before 9 AM (Tuesday/Friday) or next working day otherwise.
Test Overview & Methodology
The Centromere Antibody test uses a purified recombinant CENP-B antigen in an ELISA format to provide quantitative measurement of IgG antibodies. This method eliminates subjective interpretation inherent in indirect immunofluorescence (IFA) and enables consistent monitoring of antibody levels over time.
| Feature | Our Test (ELISA) | IFA (Alternative) |
|---|---|---|
| Precision | High quantitative sensitivity, minimal inter-observer variation | Subjective pattern interpretation, moderate sensitivity |
| Methodology | Enzyme-Linked Immunosorbent Assay (ELISA) – ISO 9001:2015 compliant | Indirect Immunofluorescence on HEp-2 cells, semi-quantitative |
| Turnaround Time | Same-day reporting (Sample by 9 AM Tue/Fri) | Usually 2–4 working days |
| Clinical Utility | Quantitative antibody levels for monitoring and diagnosis | Presence/absence only; titer may not reflect disease activity consistently |
Physician Insight & Safety Protocols
Dr. Ajay Singh
“A positive Centromere Antibody result strongly supports the diagnosis of limited systemic sclerosis (CREST syndrome), but must always be correlated with clinical symptoms such as Raynaud’s phenomenon, oesophageal dysmotility, and calcinosis. Serial quantitative monitoring can help assess disease activity and guide therapy adjustments.”
Advisory – Medication Guidance
Do not discontinue any prescribed immunosuppressive or vasodilator medication without explicit instruction from your treating physician. Abrupt cessation may worsen disease symptoms.
Exclusion Criteria & Red Flags
- Active severe infection or acute inflammatory condition (may interfere with antibody levels).
- Known current malignancy or recent chemotherapy – discuss with your specialist before testing.
- If you develop new-onset severe Raynaud’s phenomenon with digital ulcers, rapid skin thickening, or unexplained breathlessness, seek urgent rheumatology evaluation.
- Do not discontinue immunosuppressive or vasodilator therapy prior to the test without explicit physician instruction.
Patient FAQ & Clinical Guidance
1. What does a positive Centromere Antibody test mean?
A positive result strongly indicates limited systemic sclerosis (CREST syndrome) and guides further targeted organ evaluation. Your rheumatologist will use it together with clinical findings to confirm the diagnosis and monitor disease progression.
2. Is overnight fasting mandatory for this blood test?
Overnight fasting is preferred to ensure sample clarity, but non-fasting samples are still accepted with minimal impact on antibody detection. For best accuracy, however, we recommend fasting for 8–10 hours before your home collection appointment.
3. Can I get this done at home with insurance coverage?
Our hospital-grade home phlebotomy service operates daily from 8 AM to 11 PM and we verify direct billing eligibility via WhatsApp at +971 54 548 8731. Most major UAE insurers cover Centromere Antibody testing when medically necessary; our team will confirm your plan before the visit.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE complies fully with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted, access-controlled, and processed exclusively within the UAE. Clinical testing follows Federal Decree-Law No. 4 of 2016 on Medical Liability to ensure patient safety and informed consent.
Clinical & Logistical Metadata
| Test Name | Centromere Antibody (CENP-B IgG) |
| Price (AED) | 180 |
| Turnaround Time | Same-day (sample by 9 AM Tue/Fri) or next working day |
| Sample Type / Matrix | Serum (whole blood via venipuncture) |
| Methodology Used | Enzyme-Linked Immunosorbent Assay (ELISA) |
| ICD-10-CM Code | M34.1 (CREST syndrome), M34.0 (Progressive systemic sclerosis) |
| LOINC Code | 42084-2 (Centromere Ab) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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