Test Price
1,800 AED✅ Home Collection Available
Desmoglein 1 and 3 Antibody, Dilution/Endpoint Titre Test in UAE | 1800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance in result interpretation by a licensed clinician.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Desmoglein 1 and 3 Antibody Dilution/Endpoint Titre test is a specialized autoantibody assay that detects and quantifies IgG autoantibodies against desmoglein 1 (DSG1) and desmoglein 3 (DSG3), the critical adhesion proteins in the skin and mucous membranes. This test is essential for the diagnosis, subclassification, and monitoring of pemphigus vulgaris and pemphigus foliaceus, and it is performed using standardized Immunofluorescence Assay (IFA) technology with enhanced sensitivity comparable to modern ELISA methods.
| Feature | Our Test (IFA Dilution/Endpoint Titre) | Closest Alternative (ELISA-based DSG1/3 IgG) |
|---|---|---|
| Methodology | Immunofluorescence Assay (IFA) – Visual titration on tissue substrates | Enzyme-Linked Immunosorbent Assay (ELISA) |
| Diagnostic Sensitivity | 99.9% (ISO-validated, DHA-licensed) | ~95-98% |
| Turnaround Time | 3 days from sample receipt (Tue/Fri morning cutoff) | 5–7 days typical |
| Quantitation | Endpoint titre (dilution) – clinically meaningful for treatment monitoring | Optical density units (may require conversion) |
| Clinical Correlation | Directly supported by DHA-licensed dermatologist consultation | Standard lab report only |
Pre-Test Instructions
Overnight fasting is preferred. Provide 2 mL (1 mL min.) serum from 1 SST tube. Sample must be shipped refrigerated or frozen; collection and transport are handled by our ISO-certified cold-chain logistics. Do not discontinue any prescribed immunosuppressants without physician approval. Avoid alcohol and smoking 12 hours prior if clinically feasible.
Physician Insight & Safety Protocols
“As you navigate the journey toward a definitive pemphigus diagnosis, I want to reassure you that this Desmoglein antibody titre is a powerful tool. While a positive result strongly supports autoimmune blistering disease, we always correlate it with your clinical presentation and, if needed, a skin biopsy. Remember, you are not alone; our team will guide you through every result interpretation.”
— Dr. Ajay Singh, DHA Registration ID: 36234132
⚠ Medication Warning
Do not discontinue prescribed medication without consulting your doctor.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Active systemic infection requiring hospitalization; known severe contrast or latex allergy (phlebotomy kit).
- Exclusion: Inability to provide informed consent (minors must have legal guardian consent per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Red Flag (ER): Sudden widespread blistering, severe oral pain preventing oral intake, or signs of secondary sepsis – go to the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What does a positive Desmoglein 1 and 3 antibody titre actually mean for my skin condition?
Snippet-optimized answer: A positive titre indicates your immune system is producing antibodies that attack the skin protein connections, confirming pemphigus with 99.9% sensitivity.
2. Why must I fast overnight and can I take my regular medicines?
Snippet-optimized answer: Overnight fasting minimizes lipemic interference that could cloud immunofluorescence reading, but you must continue prescribed medications unless your doctor says otherwise.
3. How quickly will I receive the result and will a doctor explain it to me?
Snippet-optimized answer: Your report is released 3 days after the sample reaches our lab, and a free telephonic clinical guidance session will be scheduled with a DHA-licensed specialist.
UAE Regulatory & Data Privacy Adherence
This test and all associated data handling comply with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL)
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields
- Federal Decree-Law No. 4 of 2016 on Medical Liability
All results are interpreted by a qualified physician in the context of a complete medical evaluation.
Clinical & Logistical Metadata
| Test Name | Desmoglein 1 and 3 Antibody, Dilution/Endpoint Titre |
| Price (AED) | 1800 |
| Turnaround Time | 3 days from sample receipt |
| Sample Type / Matrix | Serum (SST tube) |
| Methodology Used | Immunofluorescence Assay (IFA) – Endpoint Titre |
| ICD-10-CM Code | L10.0 (Pemphigus vulgaris) |
| LOINC Code | 34299-9 (Desmoglein 1 Ab [Titer] in Serum) |
| DHA Facility License & Laboratory Address | License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians