Test Price
1,300 AEDโ Home Collection Available
Alpha-Aminoadipic Aciduria Test in UAE | 1300 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
The Alpha-Aminoadipic Aciduria Test delivers precise quantification of alpha-aminoadipic acid in urine and plasma via ISO 9001:2015 accredited LC-MS/MS methodology, achieving 99.9% diagnostic sensitivity for inborn errors of lysine, tryptophan, and hydroxylysine catabolism. This assay supports early detection of alpha-aminoadipic semialdehyde dehydrogenase (antiquitin) deficiency, urological stone risk stratification, and metabolic optimization for the UAEโs health-conscious population.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited LC-MS/MS Processing with isotopically labelled internal standards.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance for result interpretation and follow-up planning.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Alpha-Aminoadipic Aciduria Test uses Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) to quantify alpha-aminoadipic acid at nanomolar concentrations in urine and plasma. This advanced methodology provides superior specificity over conventional ion-exchange chromatography, enabling reliable detection of mild phenotypes and precise monitoring of therapeutic interventions for antiquitin deficiency and related metabolic disorders.
| Feature | Our Test (Alpha-Aminoadipic Aciduria Elite) | Closest Alternative (Standard Metabolic Screen) |
|---|---|---|
| Methodology | LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) โ superior specificity, quantifies at nanomolar levels | Ion-exchange chromatography with post-column ninhydrin โ less sensitive, semi-quantitative |
| Diagnostic Sensitivity | 99.9% with isotopically labelled internal standards | ~85% โ may miss mild phenotypes |
| Turnaround Time (TAT) | 2 weeks (from sample receipt) with digital report | 3โ4 weeks; often requires secondary confirmation |
| Sample Collection | VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM โ 11 PM) | Clinic visit only; no cold-chain guarantee |
| UAE Regulatory Alignment | Full DHA/MOHAP compliance, ISO 9001:2015, PDPL, and Federal Law No. 2 of 2019 aligned | May not meet updated PDPL and health data protection standards |
| Cost | 1300 AED (transparent, insurance-direct billing) | Varies; often hidden processing fees |
Physician Insight & Safety Protocols
โElevated alpha-aminoadipic acid is a critical red flag for antiquitin deficiency โ a treatable inborn error of lysine metabolism that often responds to pyridoxine therapy. However, this biomarker must always be interpreted alongside the patientโs full clinical history, nutritional status, and genetic context. Use this test as a precision guide, never as a solitary diagnosis.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
โ ๏ธ Critical Medication & Safety Advisory
Do not discontinue prescribed medication or supplements without consulting your doctor. Abrupt cessation of anti-epileptics (especially pyridoxine), amino acid supplements, or mitochondrial cofactors may trigger metabolic instability. Disclose your complete medication list to the phlebotomist prior to collection.
Exclusion Criteria & Emergency Red Flags
- Acute illness with fever, vomiting, or dehydration within 72 hours โ reschedule collection.
- Recent (<1 week) high-protein load testing or prolonged fasting (>24h) without medical supervision.
- ER Red Flags: Sudden onset of lethargy, confusion, seizures, or tachypnea in adults or children โ seek immediate emergency care; do not wait for test results.
- Co-prescription of certain anticonvulsants or valproate may interfere; disclose full medication list to the phlebotomist.
Patient FAQ & Clinical Guidance
1. What is the Alpha-Aminoadipic Aciduria Test used for?
Alpha-aminoadipic aciduria measures the concentration of alpha-aminoadipic acid in urine and plasma to screen for deficiency of alpha-aminoadipic semialdehyde dehydrogenase (antiquitin), a key enzyme in lysine, tryptophan, and hydroxylysine catabolism. Elevated levels indicate a block in the lysine degradation pathway and guide genetic counseling, dietary management, and pyridoxine responsiveness assessment.
2. How should I prepare for the sample collection?
Fasting for 8โ12 hours (only water allowed) and avoidance of high-protein meals the day before are essential to avoid transient elevations not indicative of disease. Continue all prescribed medications unless your physician advises otherwise. Our DHA-licensed phlebotomist will confirm your fasting status at the time of collection.
3. What does a high alpha-aminoadipic acid result mean?
Elevated alpha-aminoadipic acid typically points to a defect in the ALDH7A1 gene (antiquitin deficiency), often responsive to pyridoxine therapy. This finding requires immediate genetic counseling, dietary lysine restriction, and coordinated metabolic follow-up. Your referring physician will receive a comprehensive report with interpretative guidance and referral recommendations.
4. Can this test be performed during pregnancy?
Yes, with caution. Alpha-aminoadipic acid levels may physiologically shift during gestation. Inform your obstetrician and metabolic specialist before testing. Our laboratory requires explicit written consent from the referring physician for all prenatal metabolic profiling.
5. How long does it take to get results?
Turnaround time is 2 weeks from sample receipt at the laboratory. Your digital report will be delivered via secure portal with a full interpretive summary. Expedited processing is available upon request for urgent clinical cases.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143 and fully complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted, access-restricted, and processed exclusively within UAE sovereign infrastructure. Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Our ISO 9001:2015 certified quality management system ensures end-to-end traceability and audit readiness.
Clinical & Logistical Metadata
| Test Name | Alpha-Aminoadipic Aciduria Profile (Urine & Plasma) |
| Price (AED) | 1300 AED |
| Turnaround Time | 2 weeks from sample receipt |
| Sample Type / Matrix | Urine (random or timed) & Plasma (EDTA) |
| Methodology Used | LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) with isotopically labelled internal standards |
| ICD-10-CM Code | E72.3 |
| LOINC Code | 35167-5 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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