Test Price
320 AEDโ Home Collection Available
Cortisone:Cortisol Ratio Test in Dubai | 320 AED | DHA-Licensed Laboratory
Executive Summary & Core Metrics
- โAccuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- โPremium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM โ 11 PM).
- โClinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a DHA-licensed General Practitioner.
- โInsurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Cortisone:Cortisol Ratio Test precisely evaluates the activity of the enzyme 11ฮฒ-hydroxysteroid dehydrogenase (11ฮฒ-HSD) which converts inert cortisone into active cortisol, crucial for diagnosing metabolic syndrome, Cushingโs disease, and apparent mineralocorticoid excess.
Methodology: LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) โ the gold standard for adrenal steroid profiling.
Sample Requirements
2 mL (1 mL min.) serum from 1 Red Top (No Additive) tube. Overnight fasting is preferred. Diurnal variation present; sample must be collected between 8โ10 AM or 4โ6 PM. Specify exact time and date on container and request form.
Cold-Chain & Logistics
Ship refrigerated or frozen in ISO-validated cold-chain transport. Samples accepted Mon & Thu by 9 AM; reports delivered Wed & Sat respectively. Late samples will be processed in the following batch.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | LC-MS/MS โ direct measurement | Immunoassay (cross-reactivity) |
| Method | Tandem Mass Spectrometry | ELISA/CLIA |
| Speed | Report Wed / Sat after morning batch | 5โ7 working days |
Physician Insight & Safety Protocols
โAs a General Practitioner with extensive experience in metabolic and endocrine disorders, I want to emphasise that a single abnormal ratio does not define a diagnosis. This test reflects a dynamic hormonal interplay and must be interpreted alongside your clinical picture, including symptoms, medications, and any diurnal rhythm disruptions. Never self-diagnose based on numbers alone; let us correlate these results with your unique physiology to guide safe, personalised treatment.โ
โ Dr. Ajay Singh, General Practitioner | DHA Registration ID: 36234132
โ Medication Advisory
Do not discontinue prescribed medication without consulting your doctor. Abrupt changes can destabilise adrenal function and blood pressure. Always inform your phlebotomist about all medications โ especially corticosteroids, oral contraceptives, and antifungals โ as they can alter enzyme activity and invalidate the result.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Patients currently experiencing acute adrenal crisis, severe hypotension, or known glucocorticoid receptor mutations should postpone routine ratio testing until stabilised.
- Emergency Room Red Flags: If you experience sudden severe abdominal pain, vomiting, profound weakness, or mental confusion after blood draw, seek immediate ER evaluation โ these may indicate acute adrenal insufficiency or a sample-related adverse event.
- Paediatric Note: For minors, sample collection requires guardian consent per Federal Decree-Law No. 4 of 2016 on Medical Liability and DHA-approved paediatric collection protocols.
Patient FAQ & Clinical Guidance
1. What does the cortisone to cortisol ratio tell my doctor?
The ratio reveals how efficiently your body converts inactive cortisone into active cortisol, which directly influences blood pressure, glucose metabolism, and fat distribution โ key indicators in diagnosing adrenal disorders and metabolic syndrome.
2. Why must I give the sample exactly between 8โ10 AM or 4โ6 PM?
Cortisol follows a strict circadian rhythm; collecting during these peak and trough windows ensures the ratio reflects true enzymatic activity rather than random hormone fluctuations, preventing misdiagnosis of adrenal insufficiency or hypercortisolism.
3. How should I prepare for the Cortisone:Cortisol Ratio Test?
Fast overnight for at least 8โ10 hours, avoid intense physical activity and alcohol 24 hours prior, and inform your phlebotomist about all medications โ especially corticosteroids, oral contraceptives, and antifungals โ as they can alter enzyme activity and invalidate the result.
UAE Regulatory & Data Privacy Adherence
Trust & Compliance Framework
- Data Protection: All patient data is handled in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health Information Security: Adherence to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical Safety & Consent: All procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability for patient safety and informed consent.
- Accreditation: ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). Laboratory accredited by Dubai Accreditation Center (DAC).
- DHA Licensing: Fully licensed by the Dubai Health Authority under Facility License Number 1143.
Clinical & Logistical Metadata
| Test Name | Cortisone:Cortisol Ratio Test |
| Price (AED) | 320 AED |
| Turnaround Time | Results delivered every Wednesday and Saturday following morning batch processing |
| Sample Type / Matrix | Serum (2 mL from Red Top, No Additive tube) |
| Methodology Used | LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) |
| ICD-10-CM Code | E27.8, E24, E88.81 |
| LOINC Code | 104935-4 |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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