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ADAMTS13 Activity Test

Name: ADAMTS13 Activity Test
SKU: TEST-4603
Price: 4800 AED
Availability: InStock

Original price was: 5,330 د.إ.Current price is: 4,800 د.إ.

-10%

The ADAMTS13 Activity Test is a specialized blood test designed to measure the activity level of the ADAMTS13 enzyme in the blood. This enzyme plays a crucial role in the regulation of blood clotting by breaking down large protein complexes called von Willebrand factor (vWF) multimers. When ADAMTS13 activity is reduced, it can lead to the accumulation of these large vWF multimers, increasing the risk of inappropriate blood clot formation, a condition known as thrombotic thrombocytopenic purpura (TTP). TTP is a rare but life-threatening disorder that requires prompt diagnosis and treatment.

The test is particularly important for diagnosing TTP and distinguishing it from other thrombotic microangiopathies (TMAs), which have similar clinical presentations but different treatment approaches. By measuring the activity of the ADAMTS13 enzyme, healthcare providers can make informed decisions regarding the most appropriate treatment strategies for affected patients.

In the United Arab Emirates, the ADAMTS13 Activity Test is available at DNA Labs UAE, a leading diagnostic and research facility known for its comprehensive range of tests and state-of-the-art technology. The cost of the ADAMTS13 Activity Test at DNA Labs UAE is 4800 AED. This investment in health can be pivotal for individuals experiencing symptoms suggestive of TTP or for those with a known risk of the disorder, providing them with a crucial diagnostic tool to guide their treatment and management plan.

Description

ADAMTS13 ACTIVITY Test – Genetic Lab, DNA Labs UAE

Test Name: ADAMTS13 ACTIVITY Test

Components: Price: 4800.0 AED

Sample Condition: 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 mins. & finally transfer the supernatant (PPP) to 1 labelled, clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Report Delivery: 4 weeks

Method: Chemiluminscent Immunoassay

Test type: Disorders of Coagulation

Doctor: Hematologist

Test Department: COAGULATION

Pre Test Information: Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Test Details:

The ADAMTS13 activity test is a laboratory test that measures the activity level of ADAMTS13, which is an enzyme involved in the breakdown of von Willebrand factor (vWF). ADAMTS13 is responsible for cutting vWF into smaller fragments, preventing the formation of blood clots. This test is primarily used to diagnose and monitor a rare blood disorder called thrombotic thrombocytopenic purpura (TTP).

In TTP, there is a deficiency or dysfunction of ADAMTS13, leading to the accumulation of large vWF multimers and the formation of blood clots in small blood vessels throughout the body. The ADAMTS13 activity test involves taking a blood sample from the patient and measuring the ability of the patient’s plasma to cleave a synthetic peptide. The activity level is expressed as a percentage, with normal levels typically ranging from 50% to 150%.

A low ADAMTS13 activity level suggests a deficiency or dysfunction of the enzyme, which is consistent with a diagnosis of TTP. However, it is important to note that other conditions, such as liver disease or certain medications, can also cause a decrease in ADAMTS13 activity.

In addition to the ADAMTS13 activity test, other tests, such as vWF antigen and vWF multimer analysis, may be performed to further evaluate the patient’s condition and determine the underlying cause of the ADAMTS13 deficiency.

Overall, the ADAMTS13 activity test is a valuable tool in the diagnosis and management of TTP, helping healthcare providers assess the patient’s risk of developing blood clots and guide appropriate treatment strategies.

Test Name	ADAMTS13 ACTIVITY Test
Components
Price	4800.0 AED
Sample Condition	3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 mins. & finally transfer the supernatant (PPP) to 1 labelled, clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Report Delivery	4 weeks
Method	Chemiluminscent Immunoassay
Test type	Disorders of Coagulation
Doctor	Hematologist
Test Department:	COAGULATION
Pre Test Information	Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Test Details	The ADAMTS13 activity test is a laboratory test that measures the activity level of ADAMTS13, which is an enzyme involved in the breakdown of von Willebrand factor (vWF). ADAMTS13 is responsible for cutting vWF into smaller fragments, preventing the formation of blood clots. This test is primarily used to diagnose and monitor a rare blood disorder called thrombotic thrombocytopenic purpura (TTP). In TTP, there is a deficiency or dysfunction of ADAMTS13, leading to the accumulation of large vWF multimers and the formation of blood clots in small blood vessels throughout the body. The ADAMTS13 activity test involves taking a blood sample from the patient and measuring the ability of the patient’s plasma to cleave a synthetic peptide. The activity level is expressed as a percentage, with normal levels typically ranging from 50% to 150%. A low ADAMTS13 activity level suggests a deficiency or dysfunction of the enzyme, which is consistent with a diagnosis of TTP. However, it is important to note that other conditions, such as liver disease or certain medications, can also cause a decrease in ADAMTS13 activity. In addition to the ADAMTS13 activity test, other tests, such as vWF antigen and vWF multimer analysis, may be performed to further evaluate the patient’s condition and determine the underlying cause of the ADAMTS13 deficiency. Overall, the ADAMTS13 activity test is a valuable tool in the diagnosis and management of TTP, helping healthcare providers assess the patient’s risk of developing blood clots and guide appropriate treatment strategies.