Test Price
700 AED✅ Home Collection Available
PML/RARA Gene FISH Test (Acute Promyelocytic Leukemia – M3) in UAE | 700 AED
Executive Summary & Core Metrics
Executive Summary
Get definitive confirmation of Acute Promyelocytic Leukemia (APL) with our ISO-accredited Fluorescence In-Situ Hybridization (FISH) test for the PML/RARA gene rearrangement. This 3‑4 day diagnostic offers 99.9% sensitivity for t(15;17) detection in bone marrow or peripheral blood samples. Results are clinically validated by DHA-licensed specialist Mr. Prabhakar Reddy, ensuring immediate treatment decisions.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
- Sample Collection: Hospital extraction only – sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Complimentary telephonic post-test clinical interpretation with a DHA specialist.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The PML/RARA FISH test detects the pathognomonic fusion gene of Acute Promyelocytic Leukemia (AML‑M3/APML) with near‑perfect diagnostic accuracy, enabling rapid initiation of life‑saving all‑trans retinoic acid (ATRA) therapy.
| Feature | Our Test (FISH) | Closest Alternative (RT-PCR) |
|---|---|---|
| Methodology | Fluorescence In‑Situ Hybridization | Quantitative Reverse‑Transcriptase PCR |
| Diagnostic Sensitivity | 99.9% for PML/RARA fusion | 95–99% (depends on transcript isoform) |
| Turnaround Time | 3–4 days | 5–7 days |
| Sample Type | Bone marrow / Peripheral blood | Bone marrow / Peripheral blood |
| Cost | 700 AED | 1,100–1,500 AED |
Physician Insight & Safety Protocols
“The PML/RARA FISH result must be interpreted within the full clinical context, including blast morphology, coagulopathy, and molecular markers. This test is the cornerstone of early APL diagnosis, but only an integrated assessment ensures safe treatment.”
— Mr. Prabhakar Reddy, Specialist Diagnostic Radiology | DHA Registration ID: 61713011
Advisory Notice
⚠️ Medication & Treatment Advisory
Do not discontinue prescribed medication, especially ATRA or anticoagulants, without consulting your doctor. Prompt initiation of therapy is critical, but dose adjustments must be guided by a hematologist.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria
- Exclusion: Active bleeding diathesis, severe thrombocytopenia (<20,000/µL) without platelet support, suspected disseminated intravascular coagulation (DIC) with hemodynamic instability.
- ER Red Flags: Sudden severe headache, visual disturbances, unexplained bruising or bleeding, signs of differentiation syndrome (fever, respiratory distress, weight gain) – seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What does a positive PML/RARA FISH result mean?
A positive PML/RARA FISH result definitively diagnoses acute promyelocytic leukemia, enabling immediate life‑saving targeted therapy. This finding is the benchmark for starting ATRA and arsenic trioxide protocols.
2. Can this be done on peripheral blood instead of bone marrow?
Peripheral blood samples can be used if blasts are present, offering a less invasive alternative. However, bone marrow aspirate remains the preferred sample for highest diagnostic sensitivity.
3. How soon can I receive my results, and will insurance cover the cost?
Results are ready in 3‑4 days, and we verify direct insurance coverage via WhatsApp instantly. Your dedicated support at +971 54 548 8731 ensures hassle‑free claims.
UAE Regulatory & Data Privacy Adherence
Data Protection & Healthcare Technology Compliance
Your personal data is protected in accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
DNA Labs UAE holds DHA Facility License No. 1143 and is committed to the highest standards of data confidentiality and clinical governance.
Clinical & Logistical Metadata
| Test Name | PML/RARA Gene FISH Test (Acute Promyelocytic Leukemia – M3) |
| Price (AED) | 700 AED |
| Turnaround Time | 3–4 days |
| Sample Type / Matrix | Bone marrow aspirate / Peripheral blood (Hospital extraction only – sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety) |
| Methodology Used | Fluorescence In‑Situ Hybridization (FISH) |
| ICD-10-CM Code | C92.40 |
| LOINC Code | 76410-7 |
| DHA Facility License & Address | DHA License No: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Corporate Lab: DNA Labs UAE |
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