DNA Labs UAE is at the forefront of genetic and immunological diagnostics, offering a wide range of tests and analyses to help patients and healthcare providers understand complex genetic information. One of the critical tests provided by DNA Labs UAE is the HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test. This test is a cornerstone in the field of transplant immunology, helping to predict and manage potential transplant rejection episodes by detecting donor-specific antibodies (DSAs) that target HLA Class I antigens.
Understanding HLA Single Antigen Bead Assay
The Human Leukocyte Antigen (HLA) system is a group of genes on chromosome 6 that encode the major histocompatibility complex (MHC) in humans. These antigens play a critical role in the immune system’s ability to distinguish between self and non-self. The HLA Single Antigen Bead Assay is a highly sensitive method used to detect and identify specific antibodies against HLA Class I antigens in the serum of patients who have undergone organ transplantation.
Symptoms Indicating the Need for DSA-SAB Class I Test
While the DSA-SAB Class I Test itself is a diagnostic tool rather than a procedure that directly relates to specific symptoms, certain clinical scenarios warrant its use. These include:
- Post-transplantation patients experiencing unexplained organ function deterioration
- Patients with a history of previous transplants
- Individuals with known sensitization events such as blood transfusions, pregnancies, or prior transplantation
- Evaluation of transplant candidates to assess the risk of antibody-mediated rejection
It is crucial for healthcare providers to recognize these scenarios as they significantly impact the management and outcome of transplant patients.
Test Cost
The cost of the HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test at DNA Labs UAE is 5150 AED. This cost reflects the sophisticated nature of the test, the expertise required to interpret the results, and the invaluable information it provides in managing transplant patients.
Importance of the DSA-SAB Class I Test
The detection of donor-specific anti-HLA antibodies is a critical component in the pre and post-transplantation evaluation process. The presence of these antibodies is associated with a higher risk of graft rejection and loss, making the DSA-SAB Class I Test an essential tool for:
- Assessing the immunological risk pre-transplantation
- Guiding the selection of appropriate donors
- Monitoring for the development of antibodies post-transplantation that could signal an impending rejection episode
- Adjusting immunosuppressive therapy accordingly to protect the graft
Conclusion
The HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test provided by DNA Labs UAE is a vital diagnostic tool in the field of transplantation. By accurately detecting and identifying donor-specific antibodies, healthcare providers can better predict and manage potential rejection episodes, ultimately improving transplant outcomes. For more information and to schedule a test, please visit DNA Labs UAE.
