Understanding Hereditary Spastic Paraplegia
Hereditary Spastic Paraplegia (HSP) is a group of inherited disorders that are characterized by progressive weakness and spasticity (stiffness) of the legs. This condition is also known as familial spastic paraparesis or Strümpell-Lorrain syndrome. HSP can vary widely in its severity and in the age at which it first appears. It is caused by mutations in genes that are involved in the normal functioning of the nerve cells in the spinal cord.
Symptoms of Hereditary Spastic Paraplegia
The symptoms of HSP can vary significantly from person to person, even among members of the same family. However, the primary symptom is progressive weakness and spasticity of the legs. Other common symptoms include:
- Difficulty walking or a change in the way a person walks
- Increased muscle tone and stiffness in the legs
- Weakness in the legs
- Reduced bladder control, which may include urinary urgency or incontinence
- Mild loss of sensation in the lower extremities
- Fatigue due to the extra effort needed to move the legs
In some cases, individuals may also experience symptoms unrelated to leg function, including:
- Problems with balance and coordination (ataxia)
- Impaired vision due to cataracts or changes in the optic nerve
- Changes in brain function, leading to issues with memory, mood, or cognitive abilities
Hereditary Spastic Paraplegia Gene Panel Test at DNA Labs UAE
To provide a definitive diagnosis of HSP, DNA Labs UAE offers the Hereditary Spastic Paraplegia Gene Panel Test. This comprehensive test screens for mutations in the various genes known to be associated with HSP. By identifying the specific genetic mutation responsible for the condition, this test can help in understanding the prognosis, and in some cases, guide treatment and management decisions.
Why Choose DNA Labs UAE for HSP Testing?
DNA Labs UAE is a leading provider of genetic testing services in the region. Our state-of-the-art laboratory is equipped with the latest technology to ensure accurate and reliable test results. Our team of expert geneticists and counselors are dedicated to providing the highest level of care and support throughout the testing process.
Cost of the Hereditary Spastic Paraplegia Gene Panel Test
The cost of the Hereditary Spastic Paraplegia Gene Panel Test at DNA Labs UAE is 7200 AED. While the cost may seem significant, the insights provided by this test can be invaluable for affected individuals and their families. It not only aids in the diagnosis but also helps in understanding the condition better, facilitating informed decisions about management and treatment.
Learn More
For more information about the Hereditary Spastic Paraplegia Gene Panel Test and other services offered by DNA Labs UAE, please visit our website at https://dnalabsuae.com/tests/hereditary-spastic-paraplegia-gene-panel-test/.
“`
