MT-ND4L Gene Mitochondrial complex I deficiency Genetic Test
Introduction
The MT-ND4L gene is a gene located in the mitochondrial DNA that encodes for a subunit of complex I, which is one of the five protein complexes involved in the electron transport chain in mitochondria. Mitochondrial complex I deficiency refers to a group of genetic disorders characterized by a defect in the function of complex I, leading to impaired energy production in cells.
Test Details
The MT-ND4L Gene Mitochondrial complex I deficiency Genetic Test is a neurogenetic test offered by DNA Labs UAE. It is used to identify mutations in the MT-ND4L gene or other genes involved in complex I function. The test is conducted using Next-Generation Sequencing (NGS) technology.
Components and Price
The test costs 4400.0 AED and requires either a blood sample, extracted DNA, or one drop of blood on an FTA Card as the sample condition.
Report Delivery
The test results are typically delivered within 3 to 4 weeks.
Method
The test utilizes NGS technology to analyze the DNA sample.
Test Type
The MT-ND4L Gene Mitochondrial complex I deficiency Genetic Test falls under the category of Neurological Disorders.
Doctor and Test Department
The test is conducted by a Neurologist and falls under the Genetics department.
Pre Test Information
Prior to the test, a clinical history of the patient is taken. Additionally, a genetic counseling session is conducted to draw a pedigree chart of family members affected with MT-ND4L Gene Mitochondrial complex I deficiency.
NGS Genetic Testing for Mitochondrial Complex I Deficiency
NGS genetic testing is a technique used to analyze multiple genes simultaneously to identify genetic variations or mutations associated with a particular disorder. In the case of mitochondrial complex I deficiency, NGS genetic testing can be used to identify mutations in the MT-ND4L gene or other genes involved in complex I function.
The NGS genetic test for mitochondrial complex I deficiency involves sequencing the DNA of the patient, typically obtained from a blood sample. The DNA is then analyzed using high-throughput sequencing technologies to identify any genetic variations or mutations in the MT-ND4L gene or other relevant genes.
These variations can help in confirming a diagnosis of mitochondrial complex I deficiency and may also provide information about the specific mutation causing the disorder.
The results of the NGS genetic test can be used for genetic counseling, as well as to guide treatment decisions and management of the disorder. It is important to note that NGS genetic testing may not identify all possible genetic variations or mutations, and additional testing or alternative approaches may be required in some cases.
| Test Name | MT-ND4L Gene Mitochondrial complex I deficiency Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Neurological Disorders |
| Doctor | Neurologist |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for MT-ND4L Gene Mitochondrial complex I deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with MT-ND4L Gene Mitochondrial complex I deficiency |
| Test Details |
The MT-ND4L gene is a gene located in the mitochondrial DNA that encodes for a subunit of complex I, which is one of the five protein complexes involved in the electron transport chain in mitochondria. Mitochondrial complex I deficiency refers to a group of genetic disorders characterized by a defect in the function of complex I, leading to impaired energy production in cells. NGS (Next-Generation Sequencing) genetic testing is a technique used to analyze multiple genes simultaneously to identify genetic variations or mutations associated with a particular disorder. In the case of mitochondrial complex I deficiency, NGS genetic testing can be used to identify mutations in the MT-ND4L gene or other genes involved in complex I function. The NGS genetic test for mitochondrial complex I deficiency involves sequencing the DNA of the patient, typically obtained from a blood sample. The DNA is then analyzed using high-throughput sequencing technologies to identify any genetic variations or mutations in the MT-ND4L gene or other relevant genes. These variations can help in confirming a diagnosis of mitochondrial complex I deficiency and may also provide information about the specific mutation causing the disorder. The results of the NGS genetic test can be used for genetic counseling, as well as to guide treatment decisions and management of the disorder. It is important to note that NGS genetic testing may not identify all possible genetic variations or mutations, and additional testing or alternative approaches may be required in some cases. |
