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Immunohistochemistry Synaptophysin Test Cost

Original price was: 460 د.إ.Current price is: 410 د.إ.

-11%

The Immunohistochemistry Synaptophysin Test is a specialized diagnostic tool used to identify the presence of synaptophysin, a protein found in the membranes of synaptic vesicles in neurons. This test is particularly significant in the field of neuropathology for the detection and characterization of neuroendocrine tumors and certain types of brain tumors, as synaptophysin is a marker for neuroendocrine cells and neoplasms. By utilizing immunohistochemistry techniques, this test enables the precise localization of synaptophysin within tissue samples, providing valuable information for diagnosis, prognosis, and treatment planning.

The test is performed in a laboratory setting where tissue samples, obtained through biopsy or surgical resection, are treated with specific antibodies that bind to synaptophysin. These antibodies are then visualized using a chromogen, resulting in a staining pattern that can be observed under a microscope. The presence, intensity, and distribution of the staining provide insights into the nature of the tissue and the presence of neuroendocrine components.

At DNA Labs UAE, the Immunohistochemistry Synaptophysin Test is offered for 410 AED. DNA Labs UAE is equipped with state-of-the-art facilities and employs highly skilled professionals to ensure accurate and reliable test results. This test is an essential tool in the diagnostic arsenal for patients suspected of having neuroendocrine tumors or related conditions, contributing to tailored treatment approaches and improved patient outcomes.

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IMMUNOHISTOCHEMISTRY SYNAPTOPHYSIN Test

Test Name: IMMUNOHISTOCHEMISTRY SYNAPTOPHYSIN Test

Components: Synaptophysin protein detection

Price: 410.0 AED

Sample Condition: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Report Delivery: Sample Daily by 6 pm; Report Block: 5 days, Tissue Biopsy: 5 days, Tissue large complex: 7 days

Method: Immunohistochemistry

Test Type: Cancer

Doctor: Oncologist, Pathologist

Test Department: DNA Labs UAE

Pre Test Information: Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Test Details

Immunohistochemistry (IHC) is a technique used to detect specific proteins in tissue samples. The synaptophysin test is used to identify and quantify the presence of synaptophysin in tissue samples, particularly in the brain. This test is commonly used in neuropathology to diagnose and classify neuroendocrine tumors and evaluate neuronal differentiation in various types of brain tumors.

To perform the synaptophysin test, tissue samples are fixed, embedded in paraffin, and sectioned into thin slices. These tissue sections are then incubated with a primary antibody specific to synaptophysin. The primary antibody binds to the synaptophysin protein if it is present in the tissue. After washing off the unbound primary antibody, a secondary antibody is applied, which is conjugated to a detection molecule, such as an enzyme or a fluorophore. This secondary antibody amplifies the signal. Finally, a chromogen or fluorescent substrate is added, which produces a visible color or fluorescence in the presence of the detection molecule, indicating the presence of synaptophysin.

The stained tissue sections are then examined under a microscope, and the presence and distribution of synaptophysin in the tissue can be assessed. The intensity and localization of the staining provide information about the functionality and organization of synapses in the tissue.

The synaptophysin test is a valuable tool in diagnosing and studying various neurological conditions, as it allows for the visualization and quantification of synapses in tissue samples. It provides important information about the presence and distribution of synaptophysin, which can aid in understanding the underlying mechanisms of neuronal function and dysfunction.

Test Name IMMUNOHISTOCHEMISTRY SYNAPTOPHYSIN Test
Components
Price 410.0 AED
Sample Condition Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Report Delivery Sample Daily by 6 pm; Report Block: 5 days Tissue Biopsy: 5 days Tissue large complex : 7 days
Method Immunohistochemistry
Test type Cancer
Doctor Oncologist, Pathologist
Test Department:
Pre Test Information Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Test Details

Immunohistochemistry (IHC) is a technique used to detect specific proteins in tissue samples. Synaptophysin is a protein found in synaptic vesicles, which are responsible for the release of neurotransmitters in neuronal synapses. The synaptophysin test is used to identify and quantify the presence of synaptophysin in tissue samples, particularly in the brain.

The synaptophysin test is commonly used in neuropathology to diagnose and classify neuroendocrine tumors, as well as to evaluate neuronal differentiation in various types of brain tumors. It can also be used to study synaptic plasticity and neuronal development in research settings.

To perform the synaptophysin test, tissue samples are fixed, embedded in paraffin, and sectioned into thin slices. These tissue sections are then incubated with a primary antibody specific to synaptophysin. The primary antibody binds to the synaptophysin protein if it is present in the tissue. After washing off the unbound primary antibody, a secondary antibody is applied, which is conjugated to a detection molecule, such as an enzyme or a fluorophore. This secondary antibody binds to the primary antibody, amplifying the signal. Finally, a chromogen or fluorescent substrate is added, which produces a visible color or fluorescence in the presence of the detection molecule, indicating the presence of synaptophysin.

The stained tissue sections are then examined under a microscope, and the presence and distribution of synaptophysin in the tissue can be assessed. The intensity and localization of the staining can provide information about the functionality and organization of synapses in the tissue.

The synaptophysin test is a valuable tool in diagnosing and studying various neurological conditions, as it allows for the visualization and quantification of synapses in tissue samples. It provides important information about the presence and distribution of synaptophysin, which can aid in understanding the underlying mechanisms of neuronal function and dysfunction.