FGF10 Gene LADD Syndrome Genetic Test
Introduction
The FGF10 gene is responsible for encoding the fibroblast growth factor 10 protein, which plays a crucial role in the development and growth of various tissues and organs during embryonic development. Mutations in this gene have been linked to a rare genetic disorder known as LADD syndrome.
LADD Syndrome
LADD syndrome, or lacrimo-auriculo-dento-digital syndrome, is a genetic disorder that affects multiple systems in the body. It is characterized by abnormalities in the tear ducts, ears, teeth, and fingers. Individuals with LADD syndrome may experience symptoms such as absent or underdeveloped tear ducts, hearing loss, dental abnormalities, and finger malformations.
NGS Technology
Next-generation sequencing (NGS) is a powerful genetic testing method that allows for the simultaneous analysis of multiple genes. It is particularly useful for identifying genetic mutations and can be used to diagnose conditions like LADD syndrome. NGS technology enables the analysis of the entire coding region of the FGF10 gene to identify any disease-causing mutations.
Test Details
The FGF10 Gene LADD Syndrome Genetic Test is conducted using NGS technology. The test requires a sample of DNA, which can be obtained through a blood sample, saliva sample, or one drop of blood on an FTA card. The sample is then sequenced using NGS technology, and the resulting data is analyzed to identify any mutations in the FGF10 gene.
Test Cost and Report Delivery
The cost of the FGF10 Gene LADD Syndrome Genetic Test is 4400.0 AED. The report delivery typically takes 3 to 4 weeks.
Test Department and Doctor
The FGF10 Gene LADD Syndrome Genetic Test is conducted in the Genetics department. The test is recommended by pediatricians.
Pre Test Information
Prior to undergoing the FGF10 Gene LADD Syndrome Genetic Test, it is important to provide the clinical history of the patient. Additionally, a genetic counseling session may be conducted to draw a pedigree chart of family members affected by LADD syndrome.
Benefits of Genetic Testing
Genetic testing for LADD syndrome using NGS technology can provide a definitive diagnosis for individuals with symptoms consistent with the condition. It can also help guide appropriate medical management and treatment. Furthermore, genetic testing can determine if family members are at risk of passing on the condition to their children.
Consultation and Interpretation of Results
It is crucial to consult with a healthcare professional or genetic counselor before undergoing genetic testing. They can provide guidance and support throughout the testing process, interpret the results, and provide information on the implications of the diagnosis for the individual and their family.
| Test Name | FGF10 Gene LADD syndrome Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Dysmorphology |
| Doctor | Pediatrics |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for FGF10 Gene LADD syndrome NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with FGF10 Gene LADD syndrome NGS Genetic DNA Test gene FGF10 |
| Test Details |
The FGF10 gene is a gene that encodes for a protein called fibroblast growth factor 10. This protein is involved in the development and growth of various tissues and organs during embryonic development. Mutations in the FGF10 gene have been associated with a condition called LADD syndrome. LADD syndrome, which stands for lacrimo-auriculo-dento-digital syndrome, is a rare genetic disorder that affects multiple systems in the body. It is characterized by abnormalities in the tear ducts, ears, teeth, and fingers. Individuals with LADD syndrome may have symptoms such as absent or underdeveloped tear ducts, hearing loss, dental abnormalities, and finger malformations. NGS, or next-generation sequencing, is a genetic testing method that allows for the analysis of multiple genes simultaneously. It is a powerful tool for identifying genetic mutations and can be used to diagnose genetic disorders such as LADD syndrome. NGS can analyze the entire coding region of the FGF10 gene to identify any disease-causing mutations. Genetic testing for LADD syndrome using NGS involves collecting a sample of DNA, usually through a blood sample or saliva sample. The DNA is then sequenced using NGS technology, and the resulting data is analyzed to identify any mutations in the FGF10 gene. The presence of disease-causing mutations can confirm a diagnosis of LADD syndrome. Genetic testing for LADD syndrome can be beneficial for individuals with symptoms consistent with the condition, as it can provide a definitive diagnosis and help guide appropriate medical management and treatment. It can also be useful for family members of affected individuals, as it can determine if they are at risk of passing on the condition to their children. It is important to note that genetic testing should be done in consultation with a healthcare professional or genetic counselor, who can provide guidance and support throughout the testing process. They can also help interpret the results and provide information on the implications of the diagnosis for the individual and their family. |
