VPS37A Gene SPG53 Genetic Test
At DNA Labs UAE, we offer the VPS37A Gene SPG53 Genetic Test for individuals suspected of having hereditary spastic paraplegia (HSP). HSP is a group of neurological disorders characterized by progressive weakness and stiffness of the legs.
Test Details
The VPS37A gene is associated with the SPG53 subtype of HSP. This gene is involved in the intracellular trafficking and sorting of proteins. Our Next-Generation Sequencing (NGS) technology allows us to analyze multiple genes simultaneously to identify mutations or variants that may be responsible for SPG53.
Components and Price
The cost of the VPS37A Gene SPG53 Genetic Test is AED 4400.0. The test requires a blood or extracted DNA sample, or one drop of blood on an FTA card. The report will be delivered within 3 to 4 weeks.
Test Type and Department
The VPS37A Gene SPG53 Genetic Test falls under the category of Neurological Disorders. It is conducted by our Genetics department, with the involvement of a Neurologist.
Pre Test Information
Prior to the test, we recommend a Genetic Counselling session to gather the clinical history of the patient and draw a pedigree chart of family members affected by SPG53. This helps us better understand the inheritance pattern and potential risk factors.
Method and Diagnosis
To perform the test, we require a DNA sample obtained through a blood or saliva sample. The DNA is then sequenced to analyze the VPS37A gene for any mutations or variants. The results of the test can confirm a diagnosis of SPG53 and provide information about the specific mutation present in the VPS37A gene.
Importance and Considerations
It is important to note that genetic testing for SPG53 is not typically performed as a stand-alone diagnostic tool. Clinical evaluation, including a thorough medical history, physical examination, and other diagnostic tests, may also be necessary to confirm a diagnosis of SPG53. Therefore, genetic counseling is recommended before and after genetic testing to help individuals understand the implications of the test results and make informed decisions.
By offering the VPS37A Gene SPG53 Genetic Test, DNA Labs UAE aims to provide valuable information for treatment decisions and to assess the likelihood of passing on the condition to future generations.
| Test Name | VPS37A Gene SPG53 Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Neurological Disorders |
| Doctor | Neurologist |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for VPS37A Gene SPG53 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with VPS37A Gene SPG53 |
| Test Details |
The VPS37A gene is associated with the SPG53 subtype of hereditary spastic paraplegia (HSP). HSP is a group of neurological disorders characterized by progressive weakness and stiffness of the legs (paraplegia) due to degeneration of the nerve fibers that control muscle movement. SPG53 is caused by mutations in the VPS37A gene, which is involved in the intracellular trafficking and sorting of proteins. NGS (Next-Generation Sequencing) genetic testing is a method used to analyze multiple genes simultaneously to identify mutations or variants that may be responsible for a particular condition. In the case of SPG53, NGS genetic testing can be performed to identify mutations in the VPS37A gene that may be causative for the disorder. This genetic test involves obtaining a DNA sample, typically through a blood or saliva sample, and then sequencing the DNA to analyze the VPS37A gene for any mutations or variants. The results of the test can help confirm a diagnosis of SPG53 and provide information about the specific mutation present in the VPS37A gene. NGS genetic testing for SPG53 can be ordered by a healthcare provider, typically a geneticist or neurologist, if there is suspicion of the condition based on clinical symptoms and family history. The test results can help guide treatment decisions and provide information about the likelihood of passing on the condition to future generations. It is important to note that genetic testing for SPG53 is typically not performed as a stand-alone diagnostic tool. Clinical evaluation, including a thorough medical history, physical examination, and other diagnostic tests, may also be necessary to confirm a diagnosis of SPG53. Genetic counseling is recommended before and after genetic testing to help individuals understand the implications of the test results and make informed decisions. |
