Prader-Willi Syndrome FISH Test
At DNA Labs UAE, we offer the Prader-Willi Syndrome FISH Test for the diagnosis of this rare genetic disorder. The test is performed using fluorescence in situ hybridization (FISH) technology, and it can help confirm the presence of certain genes associated with Prader-Willi Syndrome.
Test Details
Prader-Willi Syndrome (PWS) is caused by the deletion or inactivation of specific genes on chromosome 15. To detect these abnormalities, we use the FISH test, which is a molecular cytogenetic technique that utilizes fluorescent probes to bind to specific DNA sequences.
During the test, a sample of peripheral blood, amniotic fluid, chorionic villi, or cord blood is collected and fixed onto a slide. The slide is then treated with fluorescent probes that are complementary to the target DNA sequences on chromosome 15. If the target genes are present, the probes will bind to them and emit fluorescence when viewed under a fluorescent microscope.
The FISH test is highly accurate and considered the gold standard for diagnosing Prader-Willi Syndrome. It is recommended when a healthcare provider suspects PWS based on the individual’s clinical features, such as feeding difficulties, weak muscle tone, developmental delays, and characteristic facial features.
Test Cost
The cost of the Prader-Willi Syndrome FISH Test at DNA Labs UAE is 1050.0 AED.
Sample Condition
We accept peripheral blood, amniotic fluid, chorionic villi, and cord blood samples for the Prader-Willi Syndrome FISH Test.
Report Delivery
The test results will be delivered within 3-4 days after sample collection.
Method
The Prader-Willi Syndrome FISH Test is performed using the FISH method.
Test Type
The Prader-Willi Syndrome FISH Test is a genetics test.
Doctor
The Prader-Willi Syndrome FISH Test is conducted by our experienced oncologists.
Test Department
The Prader-Willi Syndrome FISH Test is performed in our Genetics department.
Pre Test Information
A doctor’s prescription is required for the Prader-Willi Syndrome FISH Test. However, the prescription is not applicable for surgery and pregnancy cases or individuals planning to travel abroad.
It is important to note that the FISH test can only detect specific genetic abnormalities associated with Prader-Willi Syndrome. In some cases, additional genetic testing may be required to identify other genetic causes of similar symptoms or to provide more detailed information about the specific genetic mutation involved in PWS.
For more information or to schedule a Prader-Willi Syndrome FISH Test, please contact DNA Labs UAE.
| Test Name | Prader-Willi Syndrome FISH Test |
|---|---|
| Components | Sterile container / Sterile Normal Saline Container / Sodium heparin Vacutainer (2ml) |
| Price | 1050.0 AED |
| Sample Condition | Peripheral blood\/Amniotic fluid \/ Chorionic villi \/ Cord blood |
| Report Delivery | 3-4 days |
| Method | FISH |
| Test type | Genetics |
| Doctor | Oncology |
| Test Department: | |
| Pre Test Information | Prader-Willi Syndrome (FISH) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
| Test Details |
Prader-Willi Syndrome (PWS) is a rare genetic disorder caused by the deletion or inactivation of certain genes on chromosome 15. The diagnosis of PWS can be confirmed through a fluorescence in situ hybridization (FISH) test. FISH is a molecular cytogenetic technique that uses fluorescent probes to bind to specific DNA sequences. In the case of PWS, the FISH test is used to detect the absence or abnormality of the genes on chromosome 15 that are associated with the syndrome. During the FISH test, cells from a patient’s blood or other tissue sample are collected and fixed onto a slide. The slide is then treated with specific fluorescent probes that are complementary to the target DNA sequences on chromosome 15. If the target genes are present, the probes will bind to them and emit fluorescence when viewed under a fluorescent microscope. In individuals with PWS, the FISH test will reveal a deletion or abnormality in the region of chromosome 15 associated with the syndrome. This confirms the diagnosis of PWS and helps differentiate it from other genetic disorders with similar symptoms. The FISH test for PWS is highly accurate and is considered the gold standard for diagnosing the syndrome. It is usually recommended when a healthcare provider suspects PWS based on the individual’s clinical features, such as feeding difficulties, hypotonia (weak muscle tone), developmental delays, and characteristic facial features. It is important to note that the FISH test can only detect specific genetic abnormalities associated with PWS. In some cases, additional genetic testing may be required to identify other genetic causes of similar symptoms or to provide more detailed information about the specific genetic mutation involved in PWS. |
