Oncomine Comprehensive Panel and Oncomine Tumor Mutation Burden (TMB) and MSI and PDL1 Test
Test Name: Oncomine Comprehensive Panel and Oncomine Tumor Mutation Burden (TMB) and MSI and PDL1 Test
Components: Paraffin embedded tissue blocks + EDTA Vacutainer (3 ml)
Price: 24000.0 AED
Sample Condition: Tumor tissue + Peripheral Blood
Report Delivery: 2-3 weeks
Method: NGS, Sanger Sequencing, IHC
Test type: Genetics
Doctor: Oncology
Test Department:
Pre Test Information: Oncomine Comprehensive Panel + Oncomine Tumor Mutation Burden (TMB) + MSI + PDL1 can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Test Details:
Oncomine Comprehensive Panel is a next-generation sequencing (NGS) assay that targets over 500 cancer-related genes, including known oncogenes and tumor suppressor genes. This panel can detect somatic mutations, copy number alterations, and gene fusions across various cancer types.
Oncomine Tumor Mutation Burden (TMB) is a measure of the number of mutations in the DNA of a tumor cell. High TMB has been associated with improved response to immunotherapy in some cancer types.
Microsatellite instability (MSI) is a genomic marker that reflects defects in DNA mismatch repair (MMR) pathways. MSI-high tumors have been shown to be more responsive to immunotherapy.
Programmed death-ligand 1 (PD-L1) is a protein that is expressed on the surface of some cancer cells and can interact with immune cells to suppress the immune response. PD-L1 expression has been used as a biomarker to predict response to immunotherapy.
Combining these assays can provide a comprehensive picture of the genomic landscape of a patient’s tumor, including potential biomarkers for immunotherapy response.
Test Name | Oncomine Comprehensive Panel and Oncomine Tumor mutation burden TMBand MSI and PDL1 Test |
---|---|
Components | Paraffin embedded tissue blocks + EDTA Vacutainer (3 ml) |
Price | 24000.0 AED |
Sample Condition | Tumor tissue + Peripheral Blood |
Report Delivery | 2-3 weeks |
Method | NGS, Sanger Sequencing, IHC |
Test type | Genetics |
Doctor | Oncology |
Test Department: | |
Pre Test Information | Oncomine Comprehensive Panel + Oncomine Tumor mutation burden (TMB)+ MSI + PDL1 can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
Test Details |
Oncomine Comprehensive Panel is a next-generation sequencing (NGS) assay that targets over 500 cancer-related genes, including known oncogenes and tumor suppressor genes. This panel can detect somatic mutations, copy number alterations, and gene fusions across various cancer types. Oncomine Tumor Mutation Burden (TMB) is a measure of the number of mutations in the DNA of a tumor cell. High TMB has been associated with improved response to immunotherapy in some cancer types. Microsatellite instability (MSI) is a genomic marker that reflects defects in DNA mismatch repair (MMR) pathways. MSI-high tumors have been shown to be more responsive to immunotherapy. Programmed death-ligand 1 (PD-L1) is a protein that is expressed on the surface of some cancer cells and can interact with immune cells to suppress the immune response. PD-L1 expression has been used as a biomarker to predict response to immunotherapy. Combining these assays can provide a comprehensive picture of the genomic landscape of a patient’s tumor, including potential biomarkers for immunotherapy response. |