NTRK2 Test Cost AED:1800.0 Symptoms Diagnosis
At DNA Labs UAE, we offer the NTRK2 Test at a cost of AED 1800.0. This test is used to diagnose various neurological and psychiatric disorders, as well as certain cancers.
Test Details
The NTRK2 Test, also known as neurotrophic tyrosine kinase receptor type 2 or TrkB, is a genetic test that analyzes paraffin embedded tissue blocks. The test is performed using the FISH method and falls under the category of Genetics.
Sample Condition
The NTRK2 Test requires tumor tissue as the sample condition.
Report Delivery
Once the test is conducted, the report will be delivered within 7-8 days.
Doctor and Test Department
The NTRK2 Test is conducted by doctors specializing in Oncology. The test falls under the Test Department category.
Pre Test Information
A prescription from a doctor is required to undergo the NTRK2 Test. However, the prescription is not applicable for surgery and pregnancy cases, or for individuals planning to travel abroad.
About NTRK2
NTRK2, also known as neurotrophic tyrosine kinase receptor type 2 or TrkB, is a protein encoded by the NTRK2 gene. It is primarily expressed in the nervous system, including the brain, spinal cord, and peripheral nerves. NTRK2 plays a critical role in the development, survival, and function of neurons.
Activation of NTRK2 by brain-derived neurotrophic factor (BDNF) leads to the activation of downstream signaling pathways involved in cell growth, differentiation, and survival.
Alterations in NTRK2 signaling have been associated with various neurological and psychiatric disorders, such as depression, anxiety disorders, and autism spectrum disorder. NTRK2 gene fusions have also been identified in certain cancers, including colorectal cancer and glioblastoma.
Targeted therapies that inhibit NTRK2 activity have shown promising results in the treatment of these malignancies.
Overall, NTRK2 is an important protein involved in neuronal development and function. Dysregulation of NTRK2 can have significant implications for neurological and psychiatric disorders, as well as certain cancers.
| Test Name | NTRK2 Test |
|---|---|
| Components | Paraffin embedded tissue blocks |
| Price | 1800.0 AED |
| Sample Condition | Tumor tissue |
| Report Delivery | 7-8 days |
| Method | FISH |
| Test type | Genetics |
| Doctor | Oncology |
| Test Department: | |
| Pre Test Information | NTRK2 can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
| Test Details |
NTRK2, also known as neurotrophic tyrosine kinase receptor type 2 or TrkB, is a protein that is encoded by the NTRK2 gene. It is a receptor tyrosine kinase that is involved in the signaling pathways of neurotrophins, particularly brain-derived neurotrophic factor (BDNF). NTRK2 is primarily expressed in the nervous system, including the brain, spinal cord, and peripheral nerves. It plays a critical role in the development, survival, and function of neurons. Activation of NTRK2 by BDNF leads to the activation of downstream signaling pathways, including the MAPK/ERK and PI3K/Akt pathways, which are involved in cell growth, differentiation, and survival. Mutations or dysregulation of NTRK2 have been implicated in various neurological and psychiatric disorders. For example, alterations in NTRK2 signaling have been associated with depression, anxiety disorders, and neurodevelopmental disorders such as autism spectrum disorder. Additionally, NTRK2 gene fusions have been identified in certain cancers, such as colorectal cancer and glioblastoma, and targeted therapies that inhibit NTRK2 activity have shown promising results in these malignancies. Overall, NTRK2 is an important protein involved in neuronal development and function, and its dysregulation can have significant implications for neurological and psychiatric disorders as well as certain cancers. |
