IMMUNOHISTOCHEMISTRY CDX-2 Test
At DNA Labs UAE, we offer the IMMUNOHISTOCHEMISTRY CDX-2 Test for the diagnosis of colorectal cancer. This test detects the presence of the CDX-2 protein in tissue samples, helping to differentiate between primary colorectal adenocarcinoma and other types of tumors that may involve the colon or rectum.
Test Details
The CDX-2 test is an immunohistochemistry (IHC) test that involves the use of specific antibodies to detect the CDX-2 protein in tissue samples. CDX-2 is a transcription factor that plays a role in regulating the development and differentiation of the intestinal epithelium.
To perform the CDX-2 test, a tissue sample, usually obtained through a biopsy or surgical resection, is fixed in formalin and embedded in paraffin. Thin sections of the tissue are then mounted onto slides and subjected to a series of steps to prepare them for staining.
The IHC staining process involves the use of specific antibodies that bind to the CDX-2 protein. These antibodies are labeled with a chromogen or a fluorescent dye, which allows visualization of the protein under a microscope. If CDX-2 is present in the tissue sample, it will be stained and can be detected as a brown color or fluorescent signal.
The CDX-2 test results are interpreted by a pathologist, who examines the stained tissue sections under a microscope. A positive result indicates the presence of CDX-2 protein in the tissue, suggesting a primary colorectal adenocarcinoma. A negative result suggests the absence of CDX-2 protein and may indicate a different type of tumor or non-colorectal origin.
Test Components and Price
The IMMUNOHISTOCHEMISTRY CDX-2 Test is priced at 500.0 AED.
Sample Condition and Submission
To perform the test, submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block. The sample should be shipped at room temperature. Additionally, provide a copy of the Histopathology report, site of biopsy, and clinical history.
Report Delivery
The sample is delivered daily by 6 pm. The report for block samples is available within 5 days, while tissue biopsy and tissue large complex reports are available within 5 and 7 days respectively.
Test Type and Doctor
The IMMUNOHISTOCHEMISTRY CDX-2 Test falls under the category of cancer tests. It is recommended to consult with an oncologist or pathologist for this test.
Pre Test Information
Prior to the test, it is important to provide a copy of the Histopathology report, site of biopsy, and clinical history for accurate interpretation of the results.
Conclusion
The IMMUNOHISTOCHEMISTRY CDX-2 Test is a valuable tool in the diagnosis and classification of colorectal cancer. It helps guide treatment decisions and provides important prognostic information for patients. At DNA Labs UAE, we offer this test at a cost of 500.0 AED, ensuring accurate and timely results for our patients.
| Test Name | IMMUNOHISTOCHEMISTRY CDX-2 Test |
|---|---|
| Components | |
| Price | 500.0 AED |
| Sample Condition | Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Report Delivery | Sample Daily by 6 pm; Report Block: 5 days Tissue Biopsy: 5 days Tissue large complex : 7 days |
| Method | Immunohistochemistry |
| Test type | Cancer |
| Doctor | Oncologist, Pathologist |
| Test Department: | |
| Pre Test Information | Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Test Details |
The CDX-2 test is an immunohistochemistry (IHC) test used to detect the presence of the CDX-2 protein in tissue samples. CDX-2 is a transcription factor that plays a role in regulating the development and differentiation of the intestinal epithelium. The CDX-2 test is primarily used in the diagnosis of colorectal cancer. It helps to differentiate between primary colorectal adenocarcinoma and other types of tumors that may involve the colon or rectum. CDX-2 is highly expressed in normal colorectal epithelial cells and is typically absent in other types of tumors. To perform the CDX-2 test, a tissue sample, usually obtained through a biopsy or surgical resection, is fixed in formalin and embedded in paraffin. Thin sections of the tissue are then mounted onto slides and subjected to a series of steps to prepare them for staining. The IHC staining process involves the use of specific antibodies that bind to the CDX-2 protein. These antibodies are labeled with a chromogen or a fluorescent dye, which allows visualization of the protein under a microscope. If CDX-2 is present in the tissue sample, it will be stained and can be detected as a brown color or fluorescent signal. The CDX-2 test results are interpreted by a pathologist, who examines the stained tissue sections under a microscope. A positive result indicates the presence of CDX-2 protein in the tissue, suggesting a primary colorectal adenocarcinoma. A negative result suggests the absence of CDX-2 protein and may indicate a different type of tumor or non-colorectal origin. The CDX-2 test is a valuable tool in the diagnosis and classification of colorectal cancer. It helps guide treatment decisions and provides important prognostic information for patients. |